Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil

Detalhes bibliográficos
Autor(a) principal: da Silva, Leonardo Santos
Data de Publicação: 2017
Outros Autores: Santos, Deborah Veiga, Brietzke, Cristine Blume, Jacociunas, Laura Vicedo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/74414
Resumo: Introduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion. The objective of this study is to assess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Keywords: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIV
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spelling Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern BrazilPrevalence of HIV infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern BrazilCoinfectiontransfusion safetyhemocenterinfectious diseasesyphilisHIVPatologia e HemoterapiaCoinfectiontransfusion safetyhemocenterinfectious diseasesyphilisHIVIntroduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion. The objective of this study is to assess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Keywords: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIVIntroduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion.Objectives: Toassess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Key Words: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIVHCPA/FAMED/UFRGS2017-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/74414Clinical & Biomedical Research; Vol. 37 No. 4 (2017): Clinical and Biomedical ResearchClinical and Biomedical Research; v. 37 n. 4 (2017): Clinical and Biomedical Research2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSenghttps://seer.ufrgs.br/index.php/hcpa/article/view/74414/pdfCopyright (c) 2017 Clinical and Biomedical Researchinfo:eu-repo/semantics/openAccessda Silva, Leonardo SantosSantos, Deborah VeigaBrietzke, Cristine BlumeJacociunas, Laura Vicedo2024-01-19T14:24:21Zoai:seer.ufrgs.br:article/74414Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2024-01-19T14:24:21Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
Prevalence of HIV infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
title Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
spellingShingle Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
da Silva, Leonardo Santos
Coinfection
transfusion safety
hemocenter
infectious disease
syphilis
HIV
Patologia e Hemoterapia
Coinfection
transfusion safety
hemocenter
infectious disease
syphilis
HIV
title_short Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
title_full Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
title_fullStr Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
title_full_unstemmed Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
title_sort Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
author da Silva, Leonardo Santos
author_facet da Silva, Leonardo Santos
Santos, Deborah Veiga
Brietzke, Cristine Blume
Jacociunas, Laura Vicedo
author_role author
author2 Santos, Deborah Veiga
Brietzke, Cristine Blume
Jacociunas, Laura Vicedo
author2_role author
author
author
dc.contributor.author.fl_str_mv da Silva, Leonardo Santos
Santos, Deborah Veiga
Brietzke, Cristine Blume
Jacociunas, Laura Vicedo
dc.subject.por.fl_str_mv Coinfection
transfusion safety
hemocenter
infectious disease
syphilis
HIV
Patologia e Hemoterapia
Coinfection
transfusion safety
hemocenter
infectious disease
syphilis
HIV
topic Coinfection
transfusion safety
hemocenter
infectious disease
syphilis
HIV
Patologia e Hemoterapia
Coinfection
transfusion safety
hemocenter
infectious disease
syphilis
HIV
description Introduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion. The objective of this study is to assess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Keywords: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIV
publishDate 2017
dc.date.none.fl_str_mv 2017-12-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliado por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/74414
url https://seer.ufrgs.br/index.php/hcpa/article/view/74414
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/74414/pdf
dc.rights.driver.fl_str_mv Copyright (c) 2017 Clinical and Biomedical Research
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Clinical and Biomedical Research
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 37 No. 4 (2017): Clinical and Biomedical Research
Clinical and Biomedical Research; v. 37 n. 4 (2017): Clinical and Biomedical Research
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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