Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/74414 |
Resumo: | Introduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion. The objective of this study is to assess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Keywords: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIV |
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Clinical and Biomedical Research |
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Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern BrazilPrevalence of HIV infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern BrazilCoinfectiontransfusion safetyhemocenterinfectious diseasesyphilisHIVPatologia e HemoterapiaCoinfectiontransfusion safetyhemocenterinfectious diseasesyphilisHIVIntroduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion. The objective of this study is to assess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Keywords: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIVIntroduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion.Objectives: Toassess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Key Words: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIVHCPA/FAMED/UFRGS2017-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliado por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/74414Clinical & Biomedical Research; Vol. 37 No. 4 (2017): Clinical and Biomedical ResearchClinical and Biomedical Research; v. 37 n. 4 (2017): Clinical and Biomedical Research2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSenghttps://seer.ufrgs.br/index.php/hcpa/article/view/74414/pdfCopyright (c) 2017 Clinical and Biomedical Researchinfo:eu-repo/semantics/openAccessda Silva, Leonardo SantosSantos, Deborah VeigaBrietzke, Cristine BlumeJacociunas, Laura Vicedo2024-01-19T14:24:21Zoai:seer.ufrgs.br:article/74414Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2024-01-19T14:24:21Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil Prevalence of HIV infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
title |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
spellingShingle |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil da Silva, Leonardo Santos Coinfection transfusion safety hemocenter infectious disease syphilis HIV Patologia e Hemoterapia Coinfection transfusion safety hemocenter infectious disease syphilis HIV |
title_short |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
title_full |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
title_fullStr |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
title_full_unstemmed |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
title_sort |
Prevalence of hiv infection, Syphilis, and Syphilis/HIV coinfection in blood donors from a blood bank of Porto Alegre, southern Brazil |
author |
da Silva, Leonardo Santos |
author_facet |
da Silva, Leonardo Santos Santos, Deborah Veiga Brietzke, Cristine Blume Jacociunas, Laura Vicedo |
author_role |
author |
author2 |
Santos, Deborah Veiga Brietzke, Cristine Blume Jacociunas, Laura Vicedo |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
da Silva, Leonardo Santos Santos, Deborah Veiga Brietzke, Cristine Blume Jacociunas, Laura Vicedo |
dc.subject.por.fl_str_mv |
Coinfection transfusion safety hemocenter infectious disease syphilis HIV Patologia e Hemoterapia Coinfection transfusion safety hemocenter infectious disease syphilis HIV |
topic |
Coinfection transfusion safety hemocenter infectious disease syphilis HIV Patologia e Hemoterapia Coinfection transfusion safety hemocenter infectious disease syphilis HIV |
description |
Introduction: Hemotherapy consists of therapeutic treatments performed through blood transfusion. Clinical and serological screening of donors is an essential strategy to avoid transmission of infectious agents in blood transfusion. The objective of this study is to assess the seroprevalence of HIV infection, syphilis and syphilis/HIV coinfection in blood donors from a blood bank in Porto Alegre from 2014 to 2016.Methods: Retrospective analysis of all blood donors registered on a software for managing hemotherapy services (Hemodot) of the Blood Bank in the Marques Pereira Laboratory, Porto Alegre / RS, from 2014 to 2016.Results: Of the 28,173 users of the hemotherapy service during the study period, 198 (0.70%) were positive for syphilis, HIV infection, or syphilis/HIV co infection. The prevalence of positive results for syphilis was 0.3%, 0.57% and 0.70% in 2014, 2015 and 2016, respectively, and for HIV infection was 0.18%, 0.14%, and 0.16% for the same period. However, the prevalence of syphilis/HIV coinfection was not statistically significant.Conclusions: The prevalence of syphilis increased significantly from 2014 to 2016. Hovever, this did not occur with HIV infection or with coinfection. This finding may reflect the requirement of the nucleic acid technique (NAT) for HIV screening in blood banks, a procedure that has been increasing transfusion safety and reducing the window period. Further studies may shed new light on the combined use of serological tests and NAT assays in blood banks to diagnose HIV cases and syphilis/HIV coinfection.Keywords: Coinfection; transfusion safety; hemocenter; infectious disease; syphilis; HIV |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-12-15 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliado por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/74414 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/74414 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/74414/pdf |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Clinical and Biomedical Research info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Clinical and Biomedical Research |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 37 No. 4 (2017): Clinical and Biomedical Research Clinical and Biomedical Research; v. 37 n. 4 (2017): Clinical and Biomedical Research 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
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1799767054219214848 |