Influence of immediate reconstruction in the prognosis of locally advanced breast cancer

• Autor(a) principal: B. Brenelli, Henrique
• Data de Publicação: 2022
• Outros Autores: M. Keppke, Edwald, Z. Torresan, Renato, C. dos Santos, Cesar, A. Pinotti, José
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Clinical and Biomedical Research
• Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125728
• topic: Câncer de mama; reconstrução mamária; Breast cancer; immediate reconstruction

OBJECTIVE: To evaluate the influence of immediate breast reconstruction with transverse rectus abdominis myocutaneous (TRAM) flap in the prognosis of locally advanced breast cancer patients submitted to radical mastectomy. PATIENTS AND METHODS: Ninety patients were selected at the Breast Pathology Unit of the University of Campinas (CAISM - UNICAMP), from June 1982 to June 1989; 45 patients with immediate breast reconstruction with TRAM and the other 45 withoutbreast reconstruction (controls). We studied local and distant recurrence-free survival intervals and the overall survival. RESULTS: The local recurrence rate was low (6.6% for the experimental group and 4.4% for the control group). The distant recurrence rate was similar for both groups. There were no significant differences in the curves of local and distant recurrence-free survival between the two groups. We observed that recurrence was uniform during the first 5 years after mastectomy in both groups. The overall survival was approximately the same for both groups. The overall survival curve did not present significant differences between the experimental and control groups. CONCLUSION: We concluded that immediate breast reconstruction did not influence the parameters studied.