The meaning of local recurrence in conservative treatment of breast cancer

Detalhes bibliográficos
Autor(a) principal: V. Biazús, Jorge
Data de Publicação: 2022
Outros Autores: H. Menke, Carlos, A. Cavalheiro, José, L. Xavier, Nilton, Cericatto, Rodrigo, C. Bittelbrun, Ana, G. Rabin, Eliane
Tipo de documento: Artigo
Idioma: por
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/125890
Resumo: Conservative surgery associated with radiotherapy has shown overall survival rates similar to those of radical mastectomy, despite a great deal of variation in the rate of local recurrence according to different surgical approach. The free margins and absence of radiotherapy have a significant impact on local recurrence. In this review, factors associated with positive or negative outcomes are reviewed , as well diagnosis and treatment difficulties. At the moment, the best predictive factor for outcome of local recurrence is disease extension at initial diagnosis and treatment. Despite the fact that local recurrence after mastectomy is associated with systemic disease, patients with recurrence after BCT seem to have a more positive prognosis.
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spelling The meaning of local recurrence in conservative treatment of breast cancerSignificado da recidiva local no tratamento conservador do câncer de mamaCâncer de mamarecidiva localmastectomiacirurgia conservadorafatores prognósticosBreast cancerlocal recurrencemastectomyconservative surgeryprognostic factorsConservative surgery associated with radiotherapy has shown overall survival rates similar to those of radical mastectomy, despite a great deal of variation in the rate of local recurrence according to different surgical approach. The free margins and absence of radiotherapy have a significant impact on local recurrence. In this review, factors associated with positive or negative outcomes are reviewed , as well diagnosis and treatment difficulties. At the moment, the best predictive factor for outcome of local recurrence is disease extension at initial diagnosis and treatment. Despite the fact that local recurrence after mastectomy is associated with systemic disease, patients with recurrence after BCT seem to have a more positive prognosis.A cirurgia conservadora associada à radioterapia tem demonstrado sobrevida semelhante à cirurgia radical, porém com grande variação nas taxas de recidiva local, conforme o tipo de cirurgia: a redução das margens cirúrgicas e a ausência de radioterapia apresentaram influência significativa na taxa de recidiva local. Nesta revisão, são estudados os fatores relacionados – de forma positiva ou negativa – na ocorrência da recidiva local, bem como as formas de diagnóstico, tratamento e seu significado em termos de prognóstico. Atualmente, o melhor fator preditivo do desfecho da paciente que apresenta recidiva local é a extensão da doença no momento do tratamento primário; e embora a recidiva local após a mastectomia seja habitualmente um prenúncio de doença sistêmica, a paciente com recorrência após TC aparentemente tem um melhor prognóstico.HCPA/FAMED/UFRGS2022-07-18info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed Article"A Convite dos Editoresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/125890Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPAClinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/hcpa/article/view/125890/85523http://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccess V. Biazús, JorgeH. Menke, Carlos A. Cavalheiro, José L. Xavier, Nilton Cericatto, Rodrigo C. Bittelbrun, Ana G. Rabin, Eliane 2022-07-18T19:41:11Zoai:seer.ufrgs.br:article/125890Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-07-18T19:41:11Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv The meaning of local recurrence in conservative treatment of breast cancer
Significado da recidiva local no tratamento conservador do câncer de mama
title The meaning of local recurrence in conservative treatment of breast cancer
spellingShingle The meaning of local recurrence in conservative treatment of breast cancer
V. Biazús, Jorge
Câncer de mama
recidiva local
mastectomia
cirurgia conservadora
fatores prognósticos
Breast cancer
local recurrence
mastectomy
conservative surgery
prognostic factors
title_short The meaning of local recurrence in conservative treatment of breast cancer
title_full The meaning of local recurrence in conservative treatment of breast cancer
title_fullStr The meaning of local recurrence in conservative treatment of breast cancer
title_full_unstemmed The meaning of local recurrence in conservative treatment of breast cancer
title_sort The meaning of local recurrence in conservative treatment of breast cancer
author V. Biazús, Jorge
author_facet V. Biazús, Jorge
H. Menke, Carlos
A. Cavalheiro, José
L. Xavier, Nilton
Cericatto, Rodrigo
C. Bittelbrun, Ana
G. Rabin, Eliane
author_role author
author2 H. Menke, Carlos
A. Cavalheiro, José
L. Xavier, Nilton
Cericatto, Rodrigo
C. Bittelbrun, Ana
G. Rabin, Eliane
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv V. Biazús, Jorge
H. Menke, Carlos
A. Cavalheiro, José
L. Xavier, Nilton
Cericatto, Rodrigo
C. Bittelbrun, Ana
G. Rabin, Eliane
dc.subject.por.fl_str_mv Câncer de mama
recidiva local
mastectomia
cirurgia conservadora
fatores prognósticos
Breast cancer
local recurrence
mastectomy
conservative surgery
prognostic factors
topic Câncer de mama
recidiva local
mastectomia
cirurgia conservadora
fatores prognósticos
Breast cancer
local recurrence
mastectomy
conservative surgery
prognostic factors
description Conservative surgery associated with radiotherapy has shown overall survival rates similar to those of radical mastectomy, despite a great deal of variation in the rate of local recurrence according to different surgical approach. The free margins and absence of radiotherapy have a significant impact on local recurrence. In this review, factors associated with positive or negative outcomes are reviewed , as well diagnosis and treatment difficulties. At the moment, the best predictive factor for outcome of local recurrence is disease extension at initial diagnosis and treatment. Despite the fact that local recurrence after mastectomy is associated with systemic disease, patients with recurrence after BCT seem to have a more positive prognosis.
publishDate 2022
dc.date.none.fl_str_mv 2022-07-18
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article"
A Convite dos Editores
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125890
url https://seer.ufrgs.br/index.php/hcpa/article/view/125890
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/125890/85523
dc.rights.driver.fl_str_mv http://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 21 No. 2 (2001): Revista HCPA
Clinical and Biomedical Research; v. 21 n. 2 (2001): Revista HCPA
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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