Role of advanced glycation end products related to the onset of diabetic kidney disease complications

Detalhes bibliográficos
Autor(a) principal: de Paula, Maria Luiza Almeida
Data de Publicação: 2017
Outros Autores: Villela, Ana Marina Rodrigues, Negri, Mauricio Massucati, Kanaan, Salim, Weide, Luciene de Carvalho Cardoso
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinical and Biomedical Research
Texto Completo: https://seer.ufrgs.br/index.php/hcpa/article/view/74457
Resumo: Advanced glycation end products are known to play an important role in the diabetes complications, such as diabetic nephropathy. Most known pathways of diabetic complications involve oxidative stress, that have pivotal role in cell dysfunction onset and progression of angiopathies. This review will explore how AGEs cause endothelial dysfunction in diabetes and what current biochemical mechanisms have been proposed as an explanation for the development of diabetic nephropathy.Keywords: Type 2 diabetes mellitus; advanced glycation end products; endothelial dysfunction; hyperglycemia; oxidative stress; vascular complication; diabetic nephropathy 
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spelling Role of advanced glycation end products related to the onset of diabetic kidney disease complicationsType 2 diabetes mellitusadvanced glycation end productsendothelial dysfunctionhyperglycemiaoxidative stressvascular complicationdiabetic nephropathyEndocrinologyAdvanced glycation end products are known to play an important role in the diabetes complications, such as diabetic nephropathy. Most known pathways of diabetic complications involve oxidative stress, that have pivotal role in cell dysfunction onset and progression of angiopathies. This review will explore how AGEs cause endothelial dysfunction in diabetes and what current biochemical mechanisms have been proposed as an explanation for the development of diabetic nephropathy.Keywords: Type 2 diabetes mellitus; advanced glycation end products; endothelial dysfunction; hyperglycemia; oxidative stress; vascular complication; diabetic nephropathy HCPA/FAMED/UFRGS2017-12-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliados por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/74457Clinical & Biomedical Research; Vol. 37 No. 4 (2017): Clinical and Biomedical ResearchClinical and Biomedical Research; v. 37 n. 4 (2017): Clinical and Biomedical Research2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSenghttps://seer.ufrgs.br/index.php/hcpa/article/view/74457/pdfCopyright (c) 2017 Clinical and Biomedical Researchinfo:eu-repo/semantics/openAccessde Paula, Maria Luiza AlmeidaVillela, Ana Marina RodriguesNegri, Mauricio MassucatiKanaan, SalimWeide, Luciene de Carvalho Cardoso2024-01-19T14:24:21Zoai:seer.ufrgs.br:article/74457Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2024-01-19T14:24:21Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Role of advanced glycation end products related to the onset of diabetic kidney disease complications
title Role of advanced glycation end products related to the onset of diabetic kidney disease complications
spellingShingle Role of advanced glycation end products related to the onset of diabetic kidney disease complications
de Paula, Maria Luiza Almeida
Type 2 diabetes mellitus
advanced glycation end products
endothelial dysfunction
hyperglycemia
oxidative stress
vascular complication
diabetic nephropathy
Endocrinology
title_short Role of advanced glycation end products related to the onset of diabetic kidney disease complications
title_full Role of advanced glycation end products related to the onset of diabetic kidney disease complications
title_fullStr Role of advanced glycation end products related to the onset of diabetic kidney disease complications
title_full_unstemmed Role of advanced glycation end products related to the onset of diabetic kidney disease complications
title_sort Role of advanced glycation end products related to the onset of diabetic kidney disease complications
author de Paula, Maria Luiza Almeida
author_facet de Paula, Maria Luiza Almeida
Villela, Ana Marina Rodrigues
Negri, Mauricio Massucati
Kanaan, Salim
Weide, Luciene de Carvalho Cardoso
author_role author
author2 Villela, Ana Marina Rodrigues
Negri, Mauricio Massucati
Kanaan, Salim
Weide, Luciene de Carvalho Cardoso
author2_role author
author
author
author
dc.contributor.author.fl_str_mv de Paula, Maria Luiza Almeida
Villela, Ana Marina Rodrigues
Negri, Mauricio Massucati
Kanaan, Salim
Weide, Luciene de Carvalho Cardoso
dc.subject.por.fl_str_mv Type 2 diabetes mellitus
advanced glycation end products
endothelial dysfunction
hyperglycemia
oxidative stress
vascular complication
diabetic nephropathy
Endocrinology
topic Type 2 diabetes mellitus
advanced glycation end products
endothelial dysfunction
hyperglycemia
oxidative stress
vascular complication
diabetic nephropathy
Endocrinology
description Advanced glycation end products are known to play an important role in the diabetes complications, such as diabetic nephropathy. Most known pathways of diabetic complications involve oxidative stress, that have pivotal role in cell dysfunction onset and progression of angiopathies. This review will explore how AGEs cause endothelial dysfunction in diabetes and what current biochemical mechanisms have been proposed as an explanation for the development of diabetic nephropathy.Keywords: Type 2 diabetes mellitus; advanced glycation end products; endothelial dysfunction; hyperglycemia; oxidative stress; vascular complication; diabetic nephropathy 
publishDate 2017
dc.date.none.fl_str_mv 2017-12-15
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Avaliados por Pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/74457
url https://seer.ufrgs.br/index.php/hcpa/article/view/74457
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/hcpa/article/view/74457/pdf
dc.rights.driver.fl_str_mv Copyright (c) 2017 Clinical and Biomedical Research
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Clinical and Biomedical Research
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv HCPA/FAMED/UFRGS
publisher.none.fl_str_mv HCPA/FAMED/UFRGS
dc.source.none.fl_str_mv Clinical & Biomedical Research; Vol. 37 No. 4 (2017): Clinical and Biomedical Research
Clinical and Biomedical Research; v. 37 n. 4 (2017): Clinical and Biomedical Research
2357-9730
reponame:Clinical and Biomedical Research
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Clinical and Biomedical Research
collection Clinical and Biomedical Research
repository.name.fl_str_mv Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv ||cbr@hcpa.edu.br
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