Reduction in COVID-19 prevalence in healthcare workers in a university hospital in southern Brazil after the start of vaccination

• Autor(a) principal: Toniasso, Sheila de Castro Cardoso
• Data de Publicação: 2021
• Outros Autores: Fernandes, Fernando Schmidt, Joveleviths, Dvora, Dantas Filho, Fábio Fernandes, Takahasi, Anderson Yudi, Baldin, Camila Pereira, Pereira, Robson Martins, Silva, Luciana Pereira da, Brum, Maria Carlota Borba
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/231343
• topic: Infecções por coronavirus; Vacinação; Pessoal de saúde; COVID-19; SARS-CoV-2; Healthcare workers; Vaccine

Introduction: The quick spread of SARS-CoV-2 led to the development of vaccines that are capable of reducing infection and the number of more severe COVID-19 cases. Aim: To assess COVID-19 prevalence among healthcare workers (HCWs) after vaccination against SARS-CoV-2. Methods: This was a cross-sectional study on the prevalence of COVID-19 diagnosis among 7523 HCWs vaccinated against SARS-CoV-2 with CoronaVac and ChAdOx1 nCoV-19 in a university hospital, in southern Brazil, between January 18 and March 18, 2021.The variables evaluated were: sex, age, work area, role, source of infection, previous diagnosis of COVID-19, date of vaccine administration, type of vaccine, and need for hospitalization. The statistical analysis used Poisson regression and Fisher's exact test with SPSS software version 25, and a level of significance set at 5%. Results: 813 vaccinated HCWs showed symptoms suggestive of COVID-19, of whom 35.4% (288) had a detectable result after undergoing RT-PCR for SARS-CoV-2. There was a reduction of 62% in new cases of COVID-19 among HCWs in the institution 7 weeks after the start of vaccine rollout. Conclusion: Our data suggest that the vaccines used by the institution reduced the number of COVID-19 cases among healthcare workers, demonstrating the effectiveness of the vaccines.