Fasted exercise does not improve postprandial lipemia responses to different meals in lean and obese subjects : a crossover, randomized clinical trial

• Autor(a) principal: Lopes, André Luiz
• Data de Publicação: 2021
• Outros Autores: Macedo, Rodrigo Cauduro Oliveira, Krüger, Renata Lopes, Friedman, Rogério, Carteri, Randhall Bruce Kreismann, Oliveira, Álvaro Reischak de
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/248167
• topic: Obesidade; Exercício aeróbico; Triglicerídeos; Hiperglicemia; Tryglicerides; Hyperglycemia; Obesity

Introduction: Persistent episodes of postprandial hyperlipemia (PPL) and hyperglycemia (PPG) are considered risk factors for coronary heart disease (CHD) and premature death; whereas physical exercise improves lipid profile and glucose tolerance thus decreasing cardiovascular risks. Objective: To investigate the effects of low-intensity fasted aerobic exercise on the magnitude of the PPL and PPG responses to meals with different energy content, in normal and obese subjects. Methods: The study used a randomized crossover design. Twenty-one male (Lean: n ¼ 9, BMI: 24.3 ± 2.2; and obese: n ¼ 12, BMI 32.31 ± 2.1) volunteers aged 20e30 years, performed three interventions, separated by 7 days each: (i) 45 min at rest and isocaloric high-fat meal (60% lipids, 30% carbohydrates and 10% protein); (ii) fasted low-intensity aerobic exercise (50% VO2max) for 45 min followed by an isocaloric or (iii) calorie deficit high-fat meal. Subjects were serially assessed for blood triglycerides, and glucose levels. Results and conclusions: Low-intensity fasted aerobic exercise had no acute effect on PPL in lean and obese subjects. Glucose concentrations were reduced only in lean subjects. There is a significant dif- ference in PPL values when comparing lean to obese subjects, implying that the nutritional status in- fluences lipid and carbohydrate after fasted low-intensity aerobic exercise.