Hypertension management algorithm for type 2 diabetic patients applied in primary care
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/150423 |
Resumo: | Background: Hypertension frequently coexists with type 2 diabetes (DM), and increases the risk of cardiovascular outcomes. The aim of the study was to obtain/maintain blood pressure (BP) goals (ADA/JNC 7) according to a stepwise algorithm using the medication supplied by the Brazilian government. Methods: A one-year, single-arm interventional study conducted with type 2 diabetes patients. Intervention consisted of intensification of lifestyle changes and sequential prescription of drugs: diuretic; ACE inhibitors; β-adrenergic blocking agent and calcium channel blocking agent if BP >130/80 mmHg. Results: Seventy-eight patients completed the trial. During intervention, the number of antihypertensive tablets rose (3.6 ± 3.5 vs. 5.9 ± 3.5 pills/patient; p <0.001), as the number of antihypertensive classes increased (1.8 ± 1.0 vs. 2.70 ± 1.2; p < 0.01) and the overall drop of BP was 11 mmHg for SBP (145.0 ± 22.8 vs. 133.7 ± 20.9 mmHg; p < 0.01) and 5 mmHg for DBP (78.7 ± 11.5 vs. 73.7 ± 10.5 mmHg; p = 0.001). Although the number of patients with BP in target almost doubled [14 (18.7%) vs. 30 (38.5%) p = 0.008], less than 40% of the patients achieved the proposed goals. Conclusions: A BP algorithm applied to type 2 diabetic and hypertensive patients is able to lower BP, however more than half of the patients did not achieve the ADA/JNC 7 targets demonstrating the complexity of BP control in this population. Trial registration: ClinicalTrials.gov: NCT06260 |
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Viana, Luciana VerçozaLeitão, Cristiane BauermannGrillo, Maria de Fátima FerreiraRocha, Ennio Paulo Calearo da CostaBrenner, Juliana KellerFriedman, RogérioGross, Jorge Luiz2017-01-04T02:26:59Z20131758-5996http://hdl.handle.net/10183/150423000919855Background: Hypertension frequently coexists with type 2 diabetes (DM), and increases the risk of cardiovascular outcomes. The aim of the study was to obtain/maintain blood pressure (BP) goals (ADA/JNC 7) according to a stepwise algorithm using the medication supplied by the Brazilian government. Methods: A one-year, single-arm interventional study conducted with type 2 diabetes patients. Intervention consisted of intensification of lifestyle changes and sequential prescription of drugs: diuretic; ACE inhibitors; β-adrenergic blocking agent and calcium channel blocking agent if BP >130/80 mmHg. Results: Seventy-eight patients completed the trial. During intervention, the number of antihypertensive tablets rose (3.6 ± 3.5 vs. 5.9 ± 3.5 pills/patient; p <0.001), as the number of antihypertensive classes increased (1.8 ± 1.0 vs. 2.70 ± 1.2; p < 0.01) and the overall drop of BP was 11 mmHg for SBP (145.0 ± 22.8 vs. 133.7 ± 20.9 mmHg; p < 0.01) and 5 mmHg for DBP (78.7 ± 11.5 vs. 73.7 ± 10.5 mmHg; p = 0.001). Although the number of patients with BP in target almost doubled [14 (18.7%) vs. 30 (38.5%) p = 0.008], less than 40% of the patients achieved the proposed goals. Conclusions: A BP algorithm applied to type 2 diabetic and hypertensive patients is able to lower BP, however more than half of the patients did not achieve the ADA/JNC 7 targets demonstrating the complexity of BP control in this population. Trial registration: ClinicalTrials.gov: NCT06260application/pdfengDiabetology and metabolic syndrome. London. Vol. 5, no. 1 (Sep. 2013), 52, [5] f.Diabetes mellitus tipo 2HipertensãoAtenção primária à saúdeDoença crônicaType 2 diabetesHypertensionJNC 7ADA guidelinesReal lifeHypertension management algorithm for type 2 diabetic patients applied in primary careEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000919855.pdf000919855.pdfTexto completo (inglês)application/pdf311664http://www.lume.ufrgs.br/bitstream/10183/150423/1/000919855.pdf03b6152e4a69d687a07f4e5573a93528MD51TEXT000919855.pdf.txt000919855.pdf.txtExtracted Texttext/plain23442http://www.lume.ufrgs.br/bitstream/10183/150423/2/000919855.pdf.txtbde115bfc75f06563d7941f85866a2a1MD52THUMBNAIL000919855.pdf.jpg000919855.pdf.jpgGenerated Thumbnailimage/jpeg1939http://www.lume.ufrgs.br/bitstream/10183/150423/3/000919855.pdf.jpgdfe5073dbec6bcca896f181ed98b3ceeMD5310183/1504232024-03-07 05:03:03.820564oai:www.lume.ufrgs.br:10183/150423Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2024-03-07T08:03:03Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
title |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
spellingShingle |
Hypertension management algorithm for type 2 diabetic patients applied in primary care Viana, Luciana Verçoza Diabetes mellitus tipo 2 Hipertensão Atenção primária à saúde Doença crônica Type 2 diabetes Hypertension JNC 7 ADA guidelines Real life |
title_short |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
title_full |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
title_fullStr |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
title_full_unstemmed |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
title_sort |
Hypertension management algorithm for type 2 diabetic patients applied in primary care |
author |
Viana, Luciana Verçoza |
author_facet |
Viana, Luciana Verçoza Leitão, Cristiane Bauermann Grillo, Maria de Fátima Ferreira Rocha, Ennio Paulo Calearo da Costa Brenner, Juliana Keller Friedman, Rogério Gross, Jorge Luiz |
author_role |
author |
author2 |
Leitão, Cristiane Bauermann Grillo, Maria de Fátima Ferreira Rocha, Ennio Paulo Calearo da Costa Brenner, Juliana Keller Friedman, Rogério Gross, Jorge Luiz |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Viana, Luciana Verçoza Leitão, Cristiane Bauermann Grillo, Maria de Fátima Ferreira Rocha, Ennio Paulo Calearo da Costa Brenner, Juliana Keller Friedman, Rogério Gross, Jorge Luiz |
dc.subject.por.fl_str_mv |
Diabetes mellitus tipo 2 Hipertensão Atenção primária à saúde Doença crônica |
topic |
Diabetes mellitus tipo 2 Hipertensão Atenção primária à saúde Doença crônica Type 2 diabetes Hypertension JNC 7 ADA guidelines Real life |
dc.subject.eng.fl_str_mv |
Type 2 diabetes Hypertension JNC 7 ADA guidelines Real life |
description |
Background: Hypertension frequently coexists with type 2 diabetes (DM), and increases the risk of cardiovascular outcomes. The aim of the study was to obtain/maintain blood pressure (BP) goals (ADA/JNC 7) according to a stepwise algorithm using the medication supplied by the Brazilian government. Methods: A one-year, single-arm interventional study conducted with type 2 diabetes patients. Intervention consisted of intensification of lifestyle changes and sequential prescription of drugs: diuretic; ACE inhibitors; β-adrenergic blocking agent and calcium channel blocking agent if BP >130/80 mmHg. Results: Seventy-eight patients completed the trial. During intervention, the number of antihypertensive tablets rose (3.6 ± 3.5 vs. 5.9 ± 3.5 pills/patient; p <0.001), as the number of antihypertensive classes increased (1.8 ± 1.0 vs. 2.70 ± 1.2; p < 0.01) and the overall drop of BP was 11 mmHg for SBP (145.0 ± 22.8 vs. 133.7 ± 20.9 mmHg; p < 0.01) and 5 mmHg for DBP (78.7 ± 11.5 vs. 73.7 ± 10.5 mmHg; p = 0.001). Although the number of patients with BP in target almost doubled [14 (18.7%) vs. 30 (38.5%) p = 0.008], less than 40% of the patients achieved the proposed goals. Conclusions: A BP algorithm applied to type 2 diabetic and hypertensive patients is able to lower BP, however more than half of the patients did not achieve the ADA/JNC 7 targets demonstrating the complexity of BP control in this population. Trial registration: ClinicalTrials.gov: NCT06260 |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013 |
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2017-01-04T02:26:59Z |
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1758-5996 |
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000919855 |
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eng |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Diabetology and metabolic syndrome. London. Vol. 5, no. 1 (Sep. 2013), 52, [5] f. |
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