Myofibroblastoma arising in mammary hamartoma : a case report
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/148011 |
Resumo: | Myofibroblastoma (MFB) is a rare mesenchymal tumor arising in breast’s soft tissue with a great variety of microscopic features that can be mistaken with a wide variety of biphasic lesions. The authors report a rare case of myofibroblastoma of the breast arising in a mammary hamartoma (MH), present a review of the clinicopathological features of these lesions, and make some diagnostic considerations. The tumour consisted of a well-circumscribed nodule. MFB component comprised about fifty percent of the lesion and was made up of bipolar spindle cells arranged in fascicular clusters separated by bands of hyalinized collagen. There were fat cells and several residual hamartoma glands intermingled and distorted in MFB area. MFB component was positive for Desmin, CD34, bcl-2, and Calponin. To the best of our knowledge, MFB has not been reported in MH, neither has any of the reports described mammary glands joined within MFB. |
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Uchôa, Diego de MendonçaCruz, Dennis BaroniSchaefer, Pedro GuilhermePêgas, Karla LaisCambruzzi, Eduardo2016-09-13T02:13:54Z20102042-003Xhttp://hdl.handle.net/10183/148011001000591Myofibroblastoma (MFB) is a rare mesenchymal tumor arising in breast’s soft tissue with a great variety of microscopic features that can be mistaken with a wide variety of biphasic lesions. The authors report a rare case of myofibroblastoma of the breast arising in a mammary hamartoma (MH), present a review of the clinicopathological features of these lesions, and make some diagnostic considerations. The tumour consisted of a well-circumscribed nodule. MFB component comprised about fifty percent of the lesion and was made up of bipolar spindle cells arranged in fascicular clusters separated by bands of hyalinized collagen. There were fat cells and several residual hamartoma glands intermingled and distorted in MFB area. MFB component was positive for Desmin, CD34, bcl-2, and Calponin. To the best of our knowledge, MFB has not been reported in MH, neither has any of the reports described mammary glands joined within MFB.application/pdfengPathology research international. London. Vol. 2010 (2010), ID 726829, 4 p.Neoplasias de tecido muscularHamartomaMyofibroblastoma arising in mammary hamartoma : a case reportEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001000591.pdf001000591.pdfTexto completo (inglês)application/pdf4974331http://www.lume.ufrgs.br/bitstream/10183/148011/1/001000591.pdfd7f189d78d03054826565b2904908a7bMD51TEXT001000591.pdf.txt001000591.pdf.txtExtracted Texttext/plain17086http://www.lume.ufrgs.br/bitstream/10183/148011/2/001000591.pdf.txt4831ee16df9cab4579b92c6af0c25c88MD52THUMBNAIL001000591.pdf.jpg001000591.pdf.jpgGenerated Thumbnailimage/jpeg1684http://www.lume.ufrgs.br/bitstream/10183/148011/3/001000591.pdf.jpgf787c6d1d8a0c0f72a72cd98a2241906MD5310183/1480112018-10-29 08:50:16.651oai:www.lume.ufrgs.br:10183/148011Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-29T11:50:16Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Myofibroblastoma arising in mammary hamartoma : a case report |
title |
Myofibroblastoma arising in mammary hamartoma : a case report |
spellingShingle |
Myofibroblastoma arising in mammary hamartoma : a case report Uchôa, Diego de Mendonça Neoplasias de tecido muscular Hamartoma |
title_short |
Myofibroblastoma arising in mammary hamartoma : a case report |
title_full |
Myofibroblastoma arising in mammary hamartoma : a case report |
title_fullStr |
Myofibroblastoma arising in mammary hamartoma : a case report |
title_full_unstemmed |
Myofibroblastoma arising in mammary hamartoma : a case report |
title_sort |
Myofibroblastoma arising in mammary hamartoma : a case report |
author |
Uchôa, Diego de Mendonça |
author_facet |
Uchôa, Diego de Mendonça Cruz, Dennis Baroni Schaefer, Pedro Guilherme Pêgas, Karla Lais Cambruzzi, Eduardo |
author_role |
author |
author2 |
Cruz, Dennis Baroni Schaefer, Pedro Guilherme Pêgas, Karla Lais Cambruzzi, Eduardo |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Uchôa, Diego de Mendonça Cruz, Dennis Baroni Schaefer, Pedro Guilherme Pêgas, Karla Lais Cambruzzi, Eduardo |
dc.subject.por.fl_str_mv |
Neoplasias de tecido muscular Hamartoma |
topic |
Neoplasias de tecido muscular Hamartoma |
description |
Myofibroblastoma (MFB) is a rare mesenchymal tumor arising in breast’s soft tissue with a great variety of microscopic features that can be mistaken with a wide variety of biphasic lesions. The authors report a rare case of myofibroblastoma of the breast arising in a mammary hamartoma (MH), present a review of the clinicopathological features of these lesions, and make some diagnostic considerations. The tumour consisted of a well-circumscribed nodule. MFB component comprised about fifty percent of the lesion and was made up of bipolar spindle cells arranged in fascicular clusters separated by bands of hyalinized collagen. There were fat cells and several residual hamartoma glands intermingled and distorted in MFB area. MFB component was positive for Desmin, CD34, bcl-2, and Calponin. To the best of our knowledge, MFB has not been reported in MH, neither has any of the reports described mammary glands joined within MFB. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010 |
dc.date.accessioned.fl_str_mv |
2016-09-13T02:13:54Z |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/148011 |
dc.identifier.issn.pt_BR.fl_str_mv |
2042-003X |
dc.identifier.nrb.pt_BR.fl_str_mv |
001000591 |
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2042-003X 001000591 |
url |
http://hdl.handle.net/10183/148011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Pathology research international. London. Vol. 2010 (2010), ID 726829, 4 p. |
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openAccess |
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