Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/34315 |
Resumo: | Background: Exercise-induced left bundle branch block (EI-LBBB) is an infrequent finding. Its prevalence and prognostic significance are not clear. Objective: To evaluate, in a longitudinal study, the prevalence and prognostic significance of EI-LBBB in American war veterans. Methods: We evaluated 9,623 patients submitted to an exercise test (ET) in treadmill between 1987 and 2007. The outcomes were compared between those with normal TE, the ones with EI-LBBB and the ones with down-sloping STsegment. Mortality and causes of death were identified while blinded to the ET results. Results: In this prospective cohort, 6,922 individuals had normal ET results (57.2 ± 11.4 years), 1,739 had abnormal ST-segment depression (62.7 ± 9.8 years), and 38 had EI-LBBB (65.2 ± 11.9 years). The prevalence of EI-LBBB was 0.38%. After 8.8 years, there were 1,699 deaths due to all-cause mortality and 610 cardiovascular (CV) deaths; coronary artery disease and heart failure were more prevalent in patients with EI-LBBB. Patients with EI-BCRE had a hazard ratio of 2.37 (p = 0.002) for all-cause mortality, but it was not significant when adjusted for age or when the CV death was the assessed outcome. Conclusion: EI-LBBB is a rare clinical finding. Individuals with BCRE-EI have higher all-cause mortality when compared to those with normal ET results. However, this fact is explained by the fact that these patients are significantly older and have more associated cardiovascular diseases. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0) |
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Stein, RicardoHo, MichaelOliveira, Cristiano Machado deRibeiro, Jorge PintoLata, KusumAbelha, JoshuaOlson, HaroldMyers, Jonathan N.2011-11-11T01:19:27Z20110066-782Xhttp://hdl.handle.net/10183/34315000787375Background: Exercise-induced left bundle branch block (EI-LBBB) is an infrequent finding. Its prevalence and prognostic significance are not clear. Objective: To evaluate, in a longitudinal study, the prevalence and prognostic significance of EI-LBBB in American war veterans. Methods: We evaluated 9,623 patients submitted to an exercise test (ET) in treadmill between 1987 and 2007. The outcomes were compared between those with normal TE, the ones with EI-LBBB and the ones with down-sloping STsegment. Mortality and causes of death were identified while blinded to the ET results. Results: In this prospective cohort, 6,922 individuals had normal ET results (57.2 ± 11.4 years), 1,739 had abnormal ST-segment depression (62.7 ± 9.8 years), and 38 had EI-LBBB (65.2 ± 11.9 years). The prevalence of EI-LBBB was 0.38%. After 8.8 years, there were 1,699 deaths due to all-cause mortality and 610 cardiovascular (CV) deaths; coronary artery disease and heart failure were more prevalent in patients with EI-LBBB. Patients with EI-BCRE had a hazard ratio of 2.37 (p = 0.002) for all-cause mortality, but it was not significant when adjusted for age or when the CV death was the assessed outcome. Conclusion: EI-LBBB is a rare clinical finding. Individuals with BCRE-EI have higher all-cause mortality when compared to those with normal ET results. However, this fact is explained by the fact that these patients are significantly older and have more associated cardiovascular diseases. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0)Fundamento: El bloqueo completo de rama izquierda esfuerzo-inducido (BCRI E-I) es un hallazgo infrecuente en el test de ejercicio y su prevalencia y significado pronóstico no son claros. Objetivo: Evaluar de forma longitudinal la prevalencia y el significado pronóstico del BCRI E-I en los hombres norteamericanos veteranos de guerra. Métodos: Evaluamos 9.623 pacientes que realizaron ergometría en cinta (TE) entre 1987 y 2007. Los resultados fueron comparados entre aquellos con TE normal (TE NL), los con BCRI E-I y los que presentaron infradesnivel del segmento ST (Dep ST) anormal. La mortalidad y la causa de las muertes fueron identificadas de forma ciega para los resultados del TE. Resultados: En esta cohorte prospectiva y después de las exclusiones, 6.922 individuos presentaron EC NL (57,2 ± 11,4 años), 1739 tuvieron Dep ST anormal (62,7 ± 9,8 años), y 32 casos de BCRI E-I fueron identificados (65,2 ± 11,9 años). La prevalencia del BCRI E-I fue del 0,38%. Después de 8,8 años, ocurrieron 1699 muertes por todas las causas y 610 muertes cardiovasculares (CV). La enfermedad arterial coronaria y la insuficiencia cardíaca fueron las más prevalentes en los pacientes con BCRI E-I. Los pacientes con BCRI E-I presentaron azar de 2,37 (p = 0,002) para la mortalidad por todas las causas, pero ella no fue significativa cuando se ajustó para la edad o cuando la mortalidad cardiovascular fue el desenlace evaluado. Conclusión: BCRI E-I es un hallazgo raro. Los individuos con BCRI E-I presentan una mayor mortalidad por todas las causas cuando se les compara con los de EC NL. Sin embargo, ese hecho se explica porque esos pacientes son significativamente más viejos y por presentar más enfermedades cardiovasculares asociadas. (Arq Bras Cardiol 2011; 97(1):26-32)application/pdfapplication/pdfengArquivos brasileiros de cardiologia. São Paulo. Vol. 97, n. 1 (jul. 2011), p. 26-32Teste de esforçoBloqueio cardíacoDoença das coronáriasDisfunção ventricular esquerdaHeart blockExercise testVeteransCoronary diseaseVentricular dysfunctionLeftTest de ejercicioTrastorno de la conducciónBloqueo de ramaBloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognósticoExercise-induced left bundle branch block : prevalence and prognosisBloqueo completo de la rama izquierda esfuerzo-inducido prevalencia y pronóstico info:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000787375.pdf000787375.pdfTexto completo (inglês)application/pdf533683http://www.lume.ufrgs.br/bitstream/10183/34315/1/000787375.pdf93fd8101bf97ad011b3ca8e091bf2a1eMD51000787375-02.pdf000787375-02.pdfTexto completo (espanhol)application/pdf372231http://www.lume.ufrgs.br/bitstream/10183/34315/2/000787375-02.pdfda1fc75c8952491c5cc8050c4cb71fafMD52TEXT000787375-02.pdf.txt000787375-02.pdf.txtExtracted Texttext/plain32490http://www.lume.ufrgs.br/bitstream/10183/34315/3/000787375-02.pdf.txt6e3719d4abbe1345b34eafa2d865718aMD53000787375.pdf.txt000787375.pdf.txtExtracted Texttext/plain27908http://www.lume.ufrgs.br/bitstream/10183/34315/4/000787375.pdf.txtc20016b177f42b3d87aef8b3618cb22aMD54THUMBNAIL000787375.pdf.jpg000787375.pdf.jpgGenerated Thumbnailimage/jpeg2009http://www.lume.ufrgs.br/bitstream/10183/34315/5/000787375.pdf.jpg456a4aeddc043ff36f48097655ff8be5MD55000787375-02.pdf.jpg000787375-02.pdf.jpgGenerated Thumbnailimage/jpeg2004http://www.lume.ufrgs.br/bitstream/10183/34315/6/000787375-02.pdf.jpg49d84fd6339a76e39e03f396a68c38a2MD5610183/343152018-10-05 08:53:36.829oai:www.lume.ufrgs.br:10183/34315Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-05T11:53:36Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
dc.title.alternative.en.fl_str_mv |
Exercise-induced left bundle branch block : prevalence and prognosis |
dc.title.alternative.es.fl_str_mv |
Bloqueo completo de la rama izquierda esfuerzo-inducido prevalencia y pronóstico |
title |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
spellingShingle |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico Stein, Ricardo Teste de esforço Bloqueio cardíaco Doença das coronárias Disfunção ventricular esquerda Heart block Exercise test Veterans Coronary disease Ventricular dysfunction Left Test de ejercicio Trastorno de la conducción Bloqueo de rama |
title_short |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
title_full |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
title_fullStr |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
title_full_unstemmed |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
title_sort |
Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico |
author |
Stein, Ricardo |
author_facet |
Stein, Ricardo Ho, Michael Oliveira, Cristiano Machado de Ribeiro, Jorge Pinto Lata, Kusum Abelha, Joshua Olson, Harold Myers, Jonathan N. |
author_role |
author |
author2 |
Ho, Michael Oliveira, Cristiano Machado de Ribeiro, Jorge Pinto Lata, Kusum Abelha, Joshua Olson, Harold Myers, Jonathan N. |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Stein, Ricardo Ho, Michael Oliveira, Cristiano Machado de Ribeiro, Jorge Pinto Lata, Kusum Abelha, Joshua Olson, Harold Myers, Jonathan N. |
dc.subject.por.fl_str_mv |
Teste de esforço Bloqueio cardíaco Doença das coronárias Disfunção ventricular esquerda |
topic |
Teste de esforço Bloqueio cardíaco Doença das coronárias Disfunção ventricular esquerda Heart block Exercise test Veterans Coronary disease Ventricular dysfunction Left Test de ejercicio Trastorno de la conducción Bloqueo de rama |
dc.subject.eng.fl_str_mv |
Heart block Exercise test Veterans Coronary disease Ventricular dysfunction Left |
dc.subject.spa.fl_str_mv |
Test de ejercicio Trastorno de la conducción Bloqueo de rama |
description |
Background: Exercise-induced left bundle branch block (EI-LBBB) is an infrequent finding. Its prevalence and prognostic significance are not clear. Objective: To evaluate, in a longitudinal study, the prevalence and prognostic significance of EI-LBBB in American war veterans. Methods: We evaluated 9,623 patients submitted to an exercise test (ET) in treadmill between 1987 and 2007. The outcomes were compared between those with normal TE, the ones with EI-LBBB and the ones with down-sloping STsegment. Mortality and causes of death were identified while blinded to the ET results. Results: In this prospective cohort, 6,922 individuals had normal ET results (57.2 ± 11.4 years), 1,739 had abnormal ST-segment depression (62.7 ± 9.8 years), and 38 had EI-LBBB (65.2 ± 11.9 years). The prevalence of EI-LBBB was 0.38%. After 8.8 years, there were 1,699 deaths due to all-cause mortality and 610 cardiovascular (CV) deaths; coronary artery disease and heart failure were more prevalent in patients with EI-LBBB. Patients with EI-BCRE had a hazard ratio of 2.37 (p = 0.002) for all-cause mortality, but it was not significant when adjusted for age or when the CV death was the assessed outcome. Conclusion: EI-LBBB is a rare clinical finding. Individuals with BCRE-EI have higher all-cause mortality when compared to those with normal ET results. However, this fact is explained by the fact that these patients are significantly older and have more associated cardiovascular diseases. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0) |
publishDate |
2011 |
dc.date.accessioned.fl_str_mv |
2011-11-11T01:19:27Z |
dc.date.issued.fl_str_mv |
2011 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/other |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/34315 |
dc.identifier.issn.pt_BR.fl_str_mv |
0066-782X |
dc.identifier.nrb.pt_BR.fl_str_mv |
000787375 |
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0066-782X 000787375 |
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http://hdl.handle.net/10183/34315 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Arquivos brasileiros de cardiologia. São Paulo. Vol. 97, n. 1 (jul. 2011), p. 26-32 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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