Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico

Detalhes bibliográficos
Autor(a) principal: Stein, Ricardo
Data de Publicação: 2011
Outros Autores: Ho, Michael, Oliveira, Cristiano Machado de, Ribeiro, Jorge Pinto, Lata, Kusum, Abelha, Joshua, Olson, Harold, Myers, Jonathan N.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/34315
Resumo: Background: Exercise-induced left bundle branch block (EI-LBBB) is an infrequent finding. Its prevalence and prognostic significance are not clear. Objective: To evaluate, in a longitudinal study, the prevalence and prognostic significance of EI-LBBB in American war veterans. Methods: We evaluated 9,623 patients submitted to an exercise test (ET) in treadmill between 1987 and 2007. The outcomes were compared between those with normal TE, the ones with EI-LBBB and the ones with down-sloping STsegment. Mortality and causes of death were identified while blinded to the ET results. Results: In this prospective cohort, 6,922 individuals had normal ET results (57.2 ± 11.4 years), 1,739 had abnormal ST-segment depression (62.7 ± 9.8 years), and 38 had EI-LBBB (65.2 ± 11.9 years). The prevalence of EI-LBBB was 0.38%. After 8.8 years, there were 1,699 deaths due to all-cause mortality and 610 cardiovascular (CV) deaths; coronary artery disease and heart failure were more prevalent in patients with EI-LBBB. Patients with EI-BCRE had a hazard ratio of 2.37 (p = 0.002) for all-cause mortality, but it was not significant when adjusted for age or when the CV death was the assessed outcome. Conclusion: EI-LBBB is a rare clinical finding. Individuals with BCRE-EI have higher all-cause mortality when compared to those with normal ET results. However, this fact is explained by the fact that these patients are significantly older and have more associated cardiovascular diseases. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0)
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spelling Stein, RicardoHo, MichaelOliveira, Cristiano Machado deRibeiro, Jorge PintoLata, KusumAbelha, JoshuaOlson, HaroldMyers, Jonathan N.2011-11-11T01:19:27Z20110066-782Xhttp://hdl.handle.net/10183/34315000787375Background: Exercise-induced left bundle branch block (EI-LBBB) is an infrequent finding. Its prevalence and prognostic significance are not clear. Objective: To evaluate, in a longitudinal study, the prevalence and prognostic significance of EI-LBBB in American war veterans. Methods: We evaluated 9,623 patients submitted to an exercise test (ET) in treadmill between 1987 and 2007. The outcomes were compared between those with normal TE, the ones with EI-LBBB and the ones with down-sloping STsegment. Mortality and causes of death were identified while blinded to the ET results. Results: In this prospective cohort, 6,922 individuals had normal ET results (57.2 ± 11.4 years), 1,739 had abnormal ST-segment depression (62.7 ± 9.8 years), and 38 had EI-LBBB (65.2 ± 11.9 years). The prevalence of EI-LBBB was 0.38%. After 8.8 years, there were 1,699 deaths due to all-cause mortality and 610 cardiovascular (CV) deaths; coronary artery disease and heart failure were more prevalent in patients with EI-LBBB. Patients with EI-BCRE had a hazard ratio of 2.37 (p = 0.002) for all-cause mortality, but it was not significant when adjusted for age or when the CV death was the assessed outcome. Conclusion: EI-LBBB is a rare clinical finding. Individuals with BCRE-EI have higher all-cause mortality when compared to those with normal ET results. However, this fact is explained by the fact that these patients are significantly older and have more associated cardiovascular diseases. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0)Fundamento: El bloqueo completo de rama izquierda esfuerzo-inducido (BCRI E-I) es un hallazgo infrecuente en el test de ejercicio y su prevalencia y significado pronóstico no son claros. Objetivo: Evaluar de forma longitudinal la prevalencia y el significado pronóstico del BCRI E-I en los hombres norteamericanos veteranos de guerra. Métodos: Evaluamos 9.623 pacientes que realizaron ergometría en cinta (TE) entre 1987 y 2007. Los resultados fueron comparados entre aquellos con TE normal (TE NL), los con BCRI E-I y los que presentaron infradesnivel del segmento ST (Dep ST) anormal. La mortalidad y la causa de las muertes fueron identificadas de forma ciega para los resultados del TE. Resultados: En esta cohorte prospectiva y después de las exclusiones, 6.922 individuos presentaron EC NL (57,2 ± 11,4 años), 1739 tuvieron Dep ST anormal (62,7 ± 9,8 años), y 32 casos de BCRI E-I fueron identificados (65,2 ± 11,9 años). La prevalencia del BCRI E-I fue del 0,38%. Después de 8,8 años, ocurrieron 1699 muertes por todas las causas y 610 muertes cardiovasculares (CV). La enfermedad arterial coronaria y la insuficiencia cardíaca fueron las más prevalentes en los pacientes con BCRI E-I. Los pacientes con BCRI E-I presentaron azar de 2,37 (p = 0,002) para la mortalidad por todas las causas, pero ella no fue significativa cuando se ajustó para la edad o cuando la mortalidad cardiovascular fue el desenlace evaluado. Conclusión: BCRI E-I es un hallazgo raro. Los individuos con BCRI E-I presentan una mayor mortalidad por todas las causas cuando se les compara con los de EC NL. Sin embargo, ese hecho se explica porque esos pacientes son significativamente más viejos y por presentar más enfermedades cardiovasculares asociadas. (Arq Bras Cardiol 2011; 97(1):26-32)application/pdfapplication/pdfengArquivos brasileiros de cardiologia. São Paulo. Vol. 97, n. 1 (jul. 2011), p. 26-32Teste de esforçoBloqueio cardíacoDoença das coronáriasDisfunção ventricular esquerdaHeart blockExercise testVeteransCoronary diseaseVentricular dysfunctionLeftTest de ejercicioTrastorno de la conducciónBloqueo de ramaBloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognósticoExercise-induced left bundle branch block : prevalence and prognosisBloqueo completo de la rama izquierda esfuerzo-inducido prevalencia y pronóstico info:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000787375.pdf000787375.pdfTexto completo (inglês)application/pdf533683http://www.lume.ufrgs.br/bitstream/10183/34315/1/000787375.pdf93fd8101bf97ad011b3ca8e091bf2a1eMD51000787375-02.pdf000787375-02.pdfTexto completo (espanhol)application/pdf372231http://www.lume.ufrgs.br/bitstream/10183/34315/2/000787375-02.pdfda1fc75c8952491c5cc8050c4cb71fafMD52TEXT000787375-02.pdf.txt000787375-02.pdf.txtExtracted Texttext/plain32490http://www.lume.ufrgs.br/bitstream/10183/34315/3/000787375-02.pdf.txt6e3719d4abbe1345b34eafa2d865718aMD53000787375.pdf.txt000787375.pdf.txtExtracted Texttext/plain27908http://www.lume.ufrgs.br/bitstream/10183/34315/4/000787375.pdf.txtc20016b177f42b3d87aef8b3618cb22aMD54THUMBNAIL000787375.pdf.jpg000787375.pdf.jpgGenerated Thumbnailimage/jpeg2009http://www.lume.ufrgs.br/bitstream/10183/34315/5/000787375.pdf.jpg456a4aeddc043ff36f48097655ff8be5MD55000787375-02.pdf.jpg000787375-02.pdf.jpgGenerated Thumbnailimage/jpeg2004http://www.lume.ufrgs.br/bitstream/10183/34315/6/000787375-02.pdf.jpg49d84fd6339a76e39e03f396a68c38a2MD5610183/343152018-10-05 08:53:36.829oai:www.lume.ufrgs.br:10183/34315Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2018-10-05T11:53:36Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
dc.title.alternative.en.fl_str_mv Exercise-induced left bundle branch block : prevalence and prognosis
dc.title.alternative.es.fl_str_mv Bloqueo completo de la rama izquierda esfuerzo-inducido prevalencia y pronóstico
title Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
spellingShingle Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
Stein, Ricardo
Teste de esforço
Bloqueio cardíaco
Doença das coronárias
Disfunção ventricular esquerda
Heart block
Exercise test
Veterans
Coronary disease
Ventricular dysfunction
Left
Test de ejercicio
Trastorno de la conducción
Bloqueo de rama
title_short Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
title_full Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
title_fullStr Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
title_full_unstemmed Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
title_sort Bloqueio completo do ramo esquerdo esforço-induzido : prevalência e prognóstico
author Stein, Ricardo
author_facet Stein, Ricardo
Ho, Michael
Oliveira, Cristiano Machado de
Ribeiro, Jorge Pinto
Lata, Kusum
Abelha, Joshua
Olson, Harold
Myers, Jonathan N.
author_role author
author2 Ho, Michael
Oliveira, Cristiano Machado de
Ribeiro, Jorge Pinto
Lata, Kusum
Abelha, Joshua
Olson, Harold
Myers, Jonathan N.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Stein, Ricardo
Ho, Michael
Oliveira, Cristiano Machado de
Ribeiro, Jorge Pinto
Lata, Kusum
Abelha, Joshua
Olson, Harold
Myers, Jonathan N.
dc.subject.por.fl_str_mv Teste de esforço
Bloqueio cardíaco
Doença das coronárias
Disfunção ventricular esquerda
topic Teste de esforço
Bloqueio cardíaco
Doença das coronárias
Disfunção ventricular esquerda
Heart block
Exercise test
Veterans
Coronary disease
Ventricular dysfunction
Left
Test de ejercicio
Trastorno de la conducción
Bloqueo de rama
dc.subject.eng.fl_str_mv Heart block
Exercise test
Veterans
Coronary disease
Ventricular dysfunction
Left
dc.subject.spa.fl_str_mv Test de ejercicio
Trastorno de la conducción
Bloqueo de rama
description Background: Exercise-induced left bundle branch block (EI-LBBB) is an infrequent finding. Its prevalence and prognostic significance are not clear. Objective: To evaluate, in a longitudinal study, the prevalence and prognostic significance of EI-LBBB in American war veterans. Methods: We evaluated 9,623 patients submitted to an exercise test (ET) in treadmill between 1987 and 2007. The outcomes were compared between those with normal TE, the ones with EI-LBBB and the ones with down-sloping STsegment. Mortality and causes of death were identified while blinded to the ET results. Results: In this prospective cohort, 6,922 individuals had normal ET results (57.2 ± 11.4 years), 1,739 had abnormal ST-segment depression (62.7 ± 9.8 years), and 38 had EI-LBBB (65.2 ± 11.9 years). The prevalence of EI-LBBB was 0.38%. After 8.8 years, there were 1,699 deaths due to all-cause mortality and 610 cardiovascular (CV) deaths; coronary artery disease and heart failure were more prevalent in patients with EI-LBBB. Patients with EI-BCRE had a hazard ratio of 2.37 (p = 0.002) for all-cause mortality, but it was not significant when adjusted for age or when the CV death was the assessed outcome. Conclusion: EI-LBBB is a rare clinical finding. Individuals with BCRE-EI have higher all-cause mortality when compared to those with normal ET results. However, this fact is explained by the fact that these patients are significantly older and have more associated cardiovascular diseases. (Arq Bras Cardiol. 2011; [online].ahead print, PP.0-0)
publishDate 2011
dc.date.accessioned.fl_str_mv 2011-11-11T01:19:27Z
dc.date.issued.fl_str_mv 2011
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dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv Arquivos brasileiros de cardiologia. São Paulo. Vol. 97, n. 1 (jul. 2011), p. 26-32
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