Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b

Detalhes bibliográficos
Autor(a) principal: Pieta, Luiza
Data de Publicação: 2018
Outros Autores: Guzman, Frank, Moya, Maria Lisseth Eguiluz, Campos, Fabrício Souza, Frazzon, Ana Paula Guedes, Frazzon, Jeverson
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/187827
Resumo: Among the four lineages described for Listeria monocytogenes (I, II, III, and IV), lineages I and II harbor the serotypes most closely related to listeriosis in humans. Serotypes 1/2b and 4b are associated with the majority of listeriosis outbreaks, and serotype 1/2a is frequently involved in food and processing plant contamination. As such, the present study utilizes phylogenetic analysis for the aim of determining genomic differences between two L. monocytogenes strains isolated in southern Brazil (serotypes 1/2a and 4b) and known reference strains (L. monocytogenes EGD-e and L. monocytogenes Scott A). The Illumina Miseq platform was used to perform genomic sequencing, and cluster analysis of orthologous groups facilitated the investigation of similarities and differences between the two serotypes studied. In line with previous research, the studied strains of serotypes 1/2a and 4b presented different proteins related to resistance and virulence that may represent adaptations to several conditions during its evolution.
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spelling Pieta, LuizaGuzman, FrankMoya, Maria Lisseth EguiluzCampos, Fabrício SouzaFrazzon, Ana Paula GuedesFrazzon, Jeverson2019-01-16T04:11:47Z2018http://hdl.handle.net/10183/187827001084235Among the four lineages described for Listeria monocytogenes (I, II, III, and IV), lineages I and II harbor the serotypes most closely related to listeriosis in humans. Serotypes 1/2b and 4b are associated with the majority of listeriosis outbreaks, and serotype 1/2a is frequently involved in food and processing plant contamination. As such, the present study utilizes phylogenetic analysis for the aim of determining genomic differences between two L. monocytogenes strains isolated in southern Brazil (serotypes 1/2a and 4b) and known reference strains (L. monocytogenes EGD-e and L. monocytogenes Scott A). The Illumina Miseq platform was used to perform genomic sequencing, and cluster analysis of orthologous groups facilitated the investigation of similarities and differences between the two serotypes studied. In line with previous research, the studied strains of serotypes 1/2a and 4b presented different proteins related to resistance and virulence that may represent adaptations to several conditions during its evolution.application/pdfengEC Microbiology. Glasgow. Vol. 14, no. 11 (2018), p. 755-766Listeria monocytogenesVirulênciaFarmacorresistência bacterianaGenoma bacterianoDefense mechanismsListeriosisNext generation sequencingOrthologsResistanceVirulenceComparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4bEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001084235.pdf.txt001084235.pdf.txtExtracted Texttext/plain47466http://www.lume.ufrgs.br/bitstream/10183/187827/2/001084235.pdf.txt84c3dd0b1a8099787dc47f1ee730f7adMD52ORIGINAL001084235.pdfTexto completo (inglês)application/pdf525820http://www.lume.ufrgs.br/bitstream/10183/187827/1/001084235.pdf16b4625f86cb3e264adc1083968cf04eMD5110183/1878272020-01-09 05:02:25.923351oai:www.lume.ufrgs.br:10183/187827Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2020-01-09T07:02:25Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
title Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
spellingShingle Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
Pieta, Luiza
Listeria monocytogenes
Virulência
Farmacorresistência bacteriana
Genoma bacteriano
Defense mechanisms
Listeriosis
Next generation sequencing
Orthologs
Resistance
Virulence
title_short Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
title_full Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
title_fullStr Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
title_full_unstemmed Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
title_sort Comparative genomics suggests differences related to resistance and virulence between food-isolated Listeria monocytogenes serotypes 1/2a and 4b
author Pieta, Luiza
author_facet Pieta, Luiza
Guzman, Frank
Moya, Maria Lisseth Eguiluz
Campos, Fabrício Souza
Frazzon, Ana Paula Guedes
Frazzon, Jeverson
author_role author
author2 Guzman, Frank
Moya, Maria Lisseth Eguiluz
Campos, Fabrício Souza
Frazzon, Ana Paula Guedes
Frazzon, Jeverson
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Pieta, Luiza
Guzman, Frank
Moya, Maria Lisseth Eguiluz
Campos, Fabrício Souza
Frazzon, Ana Paula Guedes
Frazzon, Jeverson
dc.subject.por.fl_str_mv Listeria monocytogenes
Virulência
Farmacorresistência bacteriana
Genoma bacteriano
topic Listeria monocytogenes
Virulência
Farmacorresistência bacteriana
Genoma bacteriano
Defense mechanisms
Listeriosis
Next generation sequencing
Orthologs
Resistance
Virulence
dc.subject.eng.fl_str_mv Defense mechanisms
Listeriosis
Next generation sequencing
Orthologs
Resistance
Virulence
description Among the four lineages described for Listeria monocytogenes (I, II, III, and IV), lineages I and II harbor the serotypes most closely related to listeriosis in humans. Serotypes 1/2b and 4b are associated with the majority of listeriosis outbreaks, and serotype 1/2a is frequently involved in food and processing plant contamination. As such, the present study utilizes phylogenetic analysis for the aim of determining genomic differences between two L. monocytogenes strains isolated in southern Brazil (serotypes 1/2a and 4b) and known reference strains (L. monocytogenes EGD-e and L. monocytogenes Scott A). The Illumina Miseq platform was used to perform genomic sequencing, and cluster analysis of orthologous groups facilitated the investigation of similarities and differences between the two serotypes studied. In line with previous research, the studied strains of serotypes 1/2a and 4b presented different proteins related to resistance and virulence that may represent adaptations to several conditions during its evolution.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-01-16T04:11:47Z
dc.type.driver.fl_str_mv Estrangeiro
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/187827
dc.identifier.nrb.pt_BR.fl_str_mv 001084235
url http://hdl.handle.net/10183/187827
identifier_str_mv 001084235
dc.language.iso.fl_str_mv eng
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dc.relation.ispartof.pt_BR.fl_str_mv EC Microbiology. Glasgow. Vol. 14, no. 11 (2018), p. 755-766
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
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reponame_str Repositório Institucional da UFRGS
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