Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center

Detalhes bibliográficos
Autor(a) principal: Goldani, Helena Ayako Sueno
Data de Publicação: 2022
Outros Autores: Ceza, Marília Rosso, Godoy, Liége Lessa, Giesta, Juliana Mariante, Beier, Simone, Oliveira, Juliana Ghisleni de, Nunes, Daltro Luiz Alves, Feldens, Letícia, Lucena, Iara Regina Siqueira, Taniguchi, Adriano Nori Rodrigues, Hallberg, Silvia Cristina Marceliano, Durant, Daiane Marques, Boettcher, Simone, Schneider, Márcia Andréa de Oliveira, Mello, Patrícia Piccoli de, Riberg, Mariana Galvão Lopes, Signorini, Alana Verza, Miller, Cristina, Santos, Berenice Lempek dos, Silveira, Claudete Oliveira, Morais, Maíra Cristina Machado, Laggazio, Terezinha Vieira da Conceição, Costa, Carla Cristine, Kieling, Carlos Oscar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/250375
Resumo: Objectives: Data on multidisciplinary programs dedicated to home parenteral nutrition (HPN) in Latin America are limited. This study describes the results of the first multidisciplinary pediatric intestinal rehabilitation program for HPN at a public tertiary hospital in Brazil. Methods: We retrospectively reviewed patients aged 0–18 years with intestinal failure (IF) who required parenteral nutrition (PN) for >60 days between January/2014 and December/2020. Results: Fifty-four patients were discharged on HPN (15 achieved enteral autonomy, 34 continued on HPN at the end of the study, 1 underwent intestinal transplantation, and 4 died). The median (IQR) age at the study endpoint of patients who achieved enteral autonomy was 14.1 (9.7–19) versus 34.7 (20.4–53.9) months in those who did not achieve enteral autonomy. Overall prevalence of catheter-related thrombosis was 66.7% and catheterrelated bloodstream infection rate was 0.39/1000 catheter-days. Intestinal failure-associated liver disease (IFALD) was present in 24% of all patients; none of the patients who achieved enteral autonomy had IFALD. All patients showed significant improvement in anthropometric parameters during the HPN period. The sociodemographic characteristics of the patients’ family members were mothers less than 20 years old (7.5%), schooling time more than 10 years (55.5%), and household income between 1 and 3 times the minimum wage (64.8%). The 5-year survival rate for HPN is 90%, and 27.7% of patients achieve enteral autonomy. Conclusion: The treatment of pediatric patients with IF followed by a multidisciplinary pediatric intestinal rehabilitation program with HPN is feasible and safe in the Brazilian public health system.
id UFRGS-2_b1fdabddc063be275132b5dca572d7f1
oai_identifier_str oai:www.lume.ufrgs.br:10183/250375
network_acronym_str UFRGS-2
network_name_str Repositório Institucional da UFRGS
repository_id_str
spelling Goldani, Helena Ayako SuenoCeza, Marília RossoGodoy, Liége LessaGiesta, Juliana MarianteBeier, SimoneOliveira, Juliana Ghisleni deNunes, Daltro Luiz AlvesFeldens, LetíciaLucena, Iara Regina SiqueiraTaniguchi, Adriano Nori RodriguesHallberg, Silvia Cristina MarcelianoDurant, Daiane MarquesBoettcher, SimoneSchneider, Márcia Andréa de OliveiraMello, Patrícia Piccoli deRiberg, Mariana Galvão LopesSignorini, Alana VerzaMiller, CristinaSantos, Berenice Lempek dosSilveira, Claudete OliveiraMorais, Maíra Cristina MachadoLaggazio, Terezinha Vieira da ConceiçãoCosta, Carla CristineKieling, Carlos Oscar2022-10-26T04:50:14Z20220277-2116http://hdl.handle.net/10183/250375001149843Objectives: Data on multidisciplinary programs dedicated to home parenteral nutrition (HPN) in Latin America are limited. This study describes the results of the first multidisciplinary pediatric intestinal rehabilitation program for HPN at a public tertiary hospital in Brazil. Methods: We retrospectively reviewed patients aged 0–18 years with intestinal failure (IF) who required parenteral nutrition (PN) for >60 days between January/2014 and December/2020. Results: Fifty-four patients were discharged on HPN (15 achieved enteral autonomy, 34 continued on HPN at the end of the study, 1 underwent intestinal transplantation, and 4 died). The median (IQR) age at the study endpoint of patients who achieved enteral autonomy was 14.1 (9.7–19) versus 34.7 (20.4–53.9) months in those who did not achieve enteral autonomy. Overall prevalence of catheter-related thrombosis was 66.7% and catheterrelated bloodstream infection rate was 0.39/1000 catheter-days. Intestinal failure-associated liver disease (IFALD) was present in 24% of all patients; none of the patients who achieved enteral autonomy had IFALD. All patients showed significant improvement in anthropometric parameters during the HPN period. The sociodemographic characteristics of the patients’ family members were mothers less than 20 years old (7.5%), schooling time more than 10 years (55.5%), and household income between 1 and 3 times the minimum wage (64.8%). The 5-year survival rate for HPN is 90%, and 27.7% of patients achieve enteral autonomy. Conclusion: The treatment of pediatric patients with IF followed by a multidisciplinary pediatric intestinal rehabilitation program with HPN is feasible and safe in the Brazilian public health system.application/pdfengJournal of pediatric gastroenterology and nutrition. Philadelphia. Vol. 75, no. 1 (2022), p. 104-109.ReabilitaçãoInsuficiência intestinalNutrição parenteralSíndrome do intestino curtoCriançaIntestinal rehabilitationIntestinal failureShort bowel syndromeHome parenteral nutritionChildrenOutcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian centerEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001149843.pdf.txt001149843.pdf.txtExtracted Texttext/plain34759http://www.lume.ufrgs.br/bitstream/10183/250375/2/001149843.pdf.txt4a082ec720596f9e733c3c1816fe8e89MD52ORIGINAL001149843.pdfTexto completo (inglês)application/pdf421864http://www.lume.ufrgs.br/bitstream/10183/250375/1/001149843.pdf35a164c2dee95e3c6888d9f0fe8b6027MD5110183/2503752022-10-27 04:53:05.04626oai:www.lume.ufrgs.br:10183/250375Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2022-10-27T07:53:05Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
title Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
spellingShingle Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
Goldani, Helena Ayako Sueno
Reabilitação
Insuficiência intestinal
Nutrição parenteral
Síndrome do intestino curto
Criança
Intestinal rehabilitation
Intestinal failure
Short bowel syndrome
Home parenteral nutrition
Children
title_short Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
title_full Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
title_fullStr Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
title_full_unstemmed Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
title_sort Outcomes of the first 54 pediatric patients on long-term home parenteral nutrition from a single Brazilian center
author Goldani, Helena Ayako Sueno
author_facet Goldani, Helena Ayako Sueno
Ceza, Marília Rosso
Godoy, Liége Lessa
Giesta, Juliana Mariante
Beier, Simone
Oliveira, Juliana Ghisleni de
Nunes, Daltro Luiz Alves
Feldens, Letícia
Lucena, Iara Regina Siqueira
Taniguchi, Adriano Nori Rodrigues
Hallberg, Silvia Cristina Marceliano
Durant, Daiane Marques
Boettcher, Simone
Schneider, Márcia Andréa de Oliveira
Mello, Patrícia Piccoli de
Riberg, Mariana Galvão Lopes
Signorini, Alana Verza
Miller, Cristina
Santos, Berenice Lempek dos
Silveira, Claudete Oliveira
Morais, Maíra Cristina Machado
Laggazio, Terezinha Vieira da Conceição
Costa, Carla Cristine
Kieling, Carlos Oscar
author_role author
author2 Ceza, Marília Rosso
Godoy, Liége Lessa
Giesta, Juliana Mariante
Beier, Simone
Oliveira, Juliana Ghisleni de
Nunes, Daltro Luiz Alves
Feldens, Letícia
Lucena, Iara Regina Siqueira
Taniguchi, Adriano Nori Rodrigues
Hallberg, Silvia Cristina Marceliano
Durant, Daiane Marques
Boettcher, Simone
Schneider, Márcia Andréa de Oliveira
Mello, Patrícia Piccoli de
Riberg, Mariana Galvão Lopes
Signorini, Alana Verza
Miller, Cristina
Santos, Berenice Lempek dos
Silveira, Claudete Oliveira
Morais, Maíra Cristina Machado
Laggazio, Terezinha Vieira da Conceição
Costa, Carla Cristine
Kieling, Carlos Oscar
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Goldani, Helena Ayako Sueno
Ceza, Marília Rosso
Godoy, Liége Lessa
Giesta, Juliana Mariante
Beier, Simone
Oliveira, Juliana Ghisleni de
Nunes, Daltro Luiz Alves
Feldens, Letícia
Lucena, Iara Regina Siqueira
Taniguchi, Adriano Nori Rodrigues
Hallberg, Silvia Cristina Marceliano
Durant, Daiane Marques
Boettcher, Simone
Schneider, Márcia Andréa de Oliveira
Mello, Patrícia Piccoli de
Riberg, Mariana Galvão Lopes
Signorini, Alana Verza
Miller, Cristina
Santos, Berenice Lempek dos
Silveira, Claudete Oliveira
Morais, Maíra Cristina Machado
Laggazio, Terezinha Vieira da Conceição
Costa, Carla Cristine
Kieling, Carlos Oscar
dc.subject.por.fl_str_mv Reabilitação
Insuficiência intestinal
Nutrição parenteral
Síndrome do intestino curto
Criança
topic Reabilitação
Insuficiência intestinal
Nutrição parenteral
Síndrome do intestino curto
Criança
Intestinal rehabilitation
Intestinal failure
Short bowel syndrome
Home parenteral nutrition
Children
dc.subject.eng.fl_str_mv Intestinal rehabilitation
Intestinal failure
Short bowel syndrome
Home parenteral nutrition
Children
description Objectives: Data on multidisciplinary programs dedicated to home parenteral nutrition (HPN) in Latin America are limited. This study describes the results of the first multidisciplinary pediatric intestinal rehabilitation program for HPN at a public tertiary hospital in Brazil. Methods: We retrospectively reviewed patients aged 0–18 years with intestinal failure (IF) who required parenteral nutrition (PN) for >60 days between January/2014 and December/2020. Results: Fifty-four patients were discharged on HPN (15 achieved enteral autonomy, 34 continued on HPN at the end of the study, 1 underwent intestinal transplantation, and 4 died). The median (IQR) age at the study endpoint of patients who achieved enteral autonomy was 14.1 (9.7–19) versus 34.7 (20.4–53.9) months in those who did not achieve enteral autonomy. Overall prevalence of catheter-related thrombosis was 66.7% and catheterrelated bloodstream infection rate was 0.39/1000 catheter-days. Intestinal failure-associated liver disease (IFALD) was present in 24% of all patients; none of the patients who achieved enteral autonomy had IFALD. All patients showed significant improvement in anthropometric parameters during the HPN period. The sociodemographic characteristics of the patients’ family members were mothers less than 20 years old (7.5%), schooling time more than 10 years (55.5%), and household income between 1 and 3 times the minimum wage (64.8%). The 5-year survival rate for HPN is 90%, and 27.7% of patients achieve enteral autonomy. Conclusion: The treatment of pediatric patients with IF followed by a multidisciplinary pediatric intestinal rehabilitation program with HPN is feasible and safe in the Brazilian public health system.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-10-26T04:50:14Z
dc.date.issued.fl_str_mv 2022
dc.type.driver.fl_str_mv Estrangeiro
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/250375
dc.identifier.issn.pt_BR.fl_str_mv 0277-2116
dc.identifier.nrb.pt_BR.fl_str_mv 001149843
identifier_str_mv 0277-2116
001149843
url http://hdl.handle.net/10183/250375
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Journal of pediatric gastroenterology and nutrition. Philadelphia. Vol. 75, no. 1 (2022), p. 104-109.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/250375/2/001149843.pdf.txt
http://www.lume.ufrgs.br/bitstream/10183/250375/1/001149843.pdf
bitstream.checksum.fl_str_mv 4a082ec720596f9e733c3c1816fe8e89
35a164c2dee95e3c6888d9f0fe8b6027
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv
_version_ 1801225072684302336