Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility

Detalhes bibliográficos
Autor(a) principal: Hollenbach, Clarissa Boemler
Data de Publicação: 2012
Outros Autores: Bortolini, Carlos Eduardo, Rodrigues, Juliano Mattos, Hirtz, Lucas, Mello, Fernanda Bastos de, Mello, Joao Roberto Braga de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/112031
Resumo: The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner.
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spelling Hollenbach, Clarissa BoemlerBortolini, Carlos EduardoRodrigues, Juliano MattosHirtz, LucasMello, Fernanda Bastos deMello, Joao Roberto Braga de2015-03-13T01:59:00Z20122224-4700http://hdl.handle.net/10183/112031000930764The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner.El presente estudio evalúa los efectos de dos formulaciones comerciales que contienen fitoterapéuticos Glycine max (L.) Merr. (Soja) (fitoterapéutico A y fitoterapéutico B) sobre la fertilidad de ratas Wistar. Las dosis se basaron en las recomendaciones del fabricante y el aumento en una escala logarítmica. Los animales se dividieron en seis grupos experimentales y un grupo control, que recibió agua destilada. Tres grupos fueron tratados con un fitoterapéutico y tres grupos fueron tratados con fitoterapéutico B. Las dosis fueron: 4.3mg.kg-1.day-1, 21,5 mg.kg-1.day-1 y 43 mg.kg-1.day-1 , respectivamente, para GPA1, GPA2, GPA3 y GPB1, GPB2, GPB3. Los machos fueron tratados durante noventa y un días, antes y durante el apareamiento. Las Hembras Wistar fueron tratadas antes y durante el apareamiento, el embarazo y la lactancia. Número total de espermatozoides, la producción diaria de espermatozoides, la morfología del esperma, la histopatología y el peso de los órganos sexuales fueron evaluados. Los resultados mostraron la interferencia de las formulaciones fitoterapéuticos A y B en el número total de espermatozoides y en la morfología de los espermatozoides de una manera dosis-dependiente.application/pdfengRevista de salud animal. Mayabeque, Cuba. Vol. 31, no. 1 (ene./abr. 2012), p. 31-39Feijão de sojaFertilidadeMedicamentos fitoterápicos : ToxicidadeRatosSoyGlycine maxPhytotherapicMale ratsFertilityToxicitySojaFitoterapéuticosRatas machosFertilidadToxicidadEffects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertilityEfectos de dos formulaciones fitoterapéuticas que contienen Glycine max (L.) Merr sobre la fertilidad de ratas machos Estrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000930764.pdf000930764.pdfTexto completo (inglês)application/pdf138757http://www.lume.ufrgs.br/bitstream/10183/112031/1/000930764.pdf04a9f8a42c7875ec6da064d9c98772f6MD51TEXT000930764.pdf.txt000930764.pdf.txtExtracted Texttext/plain29997http://www.lume.ufrgs.br/bitstream/10183/112031/2/000930764.pdf.txt333a4007db2a7e975b7db08c2166f1beMD52THUMBNAIL000930764.pdf.jpg000930764.pdf.jpgGenerated Thumbnailimage/jpeg2129http://www.lume.ufrgs.br/bitstream/10183/112031/3/000930764.pdf.jpg981a74c47a2725be2c945b61032a7653MD5310183/1120312021-03-09 04:28:45.04545oai:www.lume.ufrgs.br:10183/112031Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-03-09T07:28:45Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
dc.title.alternative.es.fl_str_mv Efectos de dos formulaciones fitoterapéuticas que contienen Glycine max (L.) Merr sobre la fertilidad de ratas machos
title Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
spellingShingle Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
Hollenbach, Clarissa Boemler
Feijão de soja
Fertilidade
Medicamentos fitoterápicos : Toxicidade
Ratos
Soy
Glycine max
Phytotherapic
Male rats
Fertility
Toxicity
Soja
Fitoterapéuticos
Ratas machos
Fertilidad
Toxicidad
title_short Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
title_full Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
title_fullStr Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
title_full_unstemmed Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
title_sort Effects of two phytotherapic formulations containing Glycine max (L.) Merr on male rat fertility
author Hollenbach, Clarissa Boemler
author_facet Hollenbach, Clarissa Boemler
Bortolini, Carlos Eduardo
Rodrigues, Juliano Mattos
Hirtz, Lucas
Mello, Fernanda Bastos de
Mello, Joao Roberto Braga de
author_role author
author2 Bortolini, Carlos Eduardo
Rodrigues, Juliano Mattos
Hirtz, Lucas
Mello, Fernanda Bastos de
Mello, Joao Roberto Braga de
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Hollenbach, Clarissa Boemler
Bortolini, Carlos Eduardo
Rodrigues, Juliano Mattos
Hirtz, Lucas
Mello, Fernanda Bastos de
Mello, Joao Roberto Braga de
dc.subject.por.fl_str_mv Feijão de soja
Fertilidade
Medicamentos fitoterápicos : Toxicidade
Ratos
topic Feijão de soja
Fertilidade
Medicamentos fitoterápicos : Toxicidade
Ratos
Soy
Glycine max
Phytotherapic
Male rats
Fertility
Toxicity
Soja
Fitoterapéuticos
Ratas machos
Fertilidad
Toxicidad
dc.subject.eng.fl_str_mv Soy
Glycine max
Phytotherapic
Male rats
Fertility
Toxicity
dc.subject.spa.fl_str_mv Soja
Fitoterapéuticos
Ratas machos
Fertilidad
Toxicidad
description The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer’s recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1 , respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2015-03-13T01:59:00Z
dc.type.driver.fl_str_mv Estrangeiro
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/112031
dc.identifier.issn.pt_BR.fl_str_mv 2224-4700
dc.identifier.nrb.pt_BR.fl_str_mv 000930764
identifier_str_mv 2224-4700
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url http://hdl.handle.net/10183/112031
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Revista de salud animal. Mayabeque, Cuba. Vol. 31, no. 1 (ene./abr. 2012), p. 31-39
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