Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism

Detalhes bibliográficos
Autor(a) principal: Weiss, Rita Vasconcellos
Data de Publicação: 2019
Outros Autores: Hohl, Alexandre, Athayde, Amanda Valéria Luna de, Pardini, Dolores Perovano, Gomes, Larissa, Oliveira, Mônica de, Meirelles, Ricardo Martins da Rocha, Clapauch, Ruth, Spritzer, Poli Mara
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/200721
Resumo: Objective: To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods: The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results: Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion: Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription.
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spelling Weiss, Rita VasconcellosHohl, AlexandreAthayde, Amanda Valéria Luna dePardini, Dolores PerovanoGomes, LarissaOliveira, Mônica deMeirelles, Ricardo Martins da RochaClapauch, RuthSpritzer, Poli Mara2019-10-12T03:55:50Z20192359-3997http://hdl.handle.net/10183/200721001103781Objective: To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods: The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results: Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion: Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription.application/pdfengArchives of endocrinology and metabolism. São Paulo. Vol. 63, no. 3 (May/June 2019), p. 190-198LibidoAssexualidadeTestosteronaFemininoTestosterone therapyFemale sexual disorderTestosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolisminfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001103781.pdf.txt001103781.pdf.txtExtracted Texttext/plain43710http://www.lume.ufrgs.br/bitstream/10183/200721/2/001103781.pdf.txtbf9da3d1cccdf0a75eaaac0cbbd4a35dMD52ORIGINAL001103781.pdfTexto completo (inglês)application/pdf151726http://www.lume.ufrgs.br/bitstream/10183/200721/1/001103781.pdfb88a0d352a6957e165d5081c234b22ebMD5110183/2007212019-10-13 03:51:12.39203oai:www.lume.ufrgs.br:10183/200721Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-10-13T06:51:12Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
title Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
spellingShingle Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
Weiss, Rita Vasconcellos
Libido
Assexualidade
Testosterona
Feminino
Testosterone therapy
Female sexual disorder
title_short Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
title_full Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
title_fullStr Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
title_full_unstemmed Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
title_sort Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
author Weiss, Rita Vasconcellos
author_facet Weiss, Rita Vasconcellos
Hohl, Alexandre
Athayde, Amanda Valéria Luna de
Pardini, Dolores Perovano
Gomes, Larissa
Oliveira, Mônica de
Meirelles, Ricardo Martins da Rocha
Clapauch, Ruth
Spritzer, Poli Mara
author_role author
author2 Hohl, Alexandre
Athayde, Amanda Valéria Luna de
Pardini, Dolores Perovano
Gomes, Larissa
Oliveira, Mônica de
Meirelles, Ricardo Martins da Rocha
Clapauch, Ruth
Spritzer, Poli Mara
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Weiss, Rita Vasconcellos
Hohl, Alexandre
Athayde, Amanda Valéria Luna de
Pardini, Dolores Perovano
Gomes, Larissa
Oliveira, Mônica de
Meirelles, Ricardo Martins da Rocha
Clapauch, Ruth
Spritzer, Poli Mara
dc.subject.por.fl_str_mv Libido
Assexualidade
Testosterona
Feminino
topic Libido
Assexualidade
Testosterona
Feminino
Testosterone therapy
Female sexual disorder
dc.subject.eng.fl_str_mv Testosterone therapy
Female sexual disorder
description Objective: To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods: The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results: Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion: Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription.
publishDate 2019
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dc.relation.ispartof.pt_BR.fl_str_mv Archives of endocrinology and metabolism. São Paulo. Vol. 63, no. 3 (May/June 2019), p. 190-198
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