Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/200721 |
Resumo: | Objective: To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods: The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results: Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion: Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription. |
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Weiss, Rita VasconcellosHohl, AlexandreAthayde, Amanda Valéria Luna dePardini, Dolores PerovanoGomes, LarissaOliveira, Mônica deMeirelles, Ricardo Martins da RochaClapauch, RuthSpritzer, Poli Mara2019-10-12T03:55:50Z20192359-3997http://hdl.handle.net/10183/200721001103781Objective: To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods: The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results: Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion: Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription.application/pdfengArchives of endocrinology and metabolism. São Paulo. Vol. 63, no. 3 (May/June 2019), p. 190-198LibidoAssexualidadeTestosteronaFemininoTestosterone therapyFemale sexual disorderTestosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolisminfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001103781.pdf.txt001103781.pdf.txtExtracted Texttext/plain43710http://www.lume.ufrgs.br/bitstream/10183/200721/2/001103781.pdf.txtbf9da3d1cccdf0a75eaaac0cbbd4a35dMD52ORIGINAL001103781.pdfTexto completo (inglês)application/pdf151726http://www.lume.ufrgs.br/bitstream/10183/200721/1/001103781.pdfb88a0d352a6957e165d5081c234b22ebMD5110183/2007212019-10-13 03:51:12.39203oai:www.lume.ufrgs.br:10183/200721Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-10-13T06:51:12Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
title |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
spellingShingle |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism Weiss, Rita Vasconcellos Libido Assexualidade Testosterona Feminino Testosterone therapy Female sexual disorder |
title_short |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
title_full |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
title_fullStr |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
title_full_unstemmed |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
title_sort |
Testosterone therapy for women with low sexual desire : a position statement from the Brazilian Society of Endocrinology and Metabolism |
author |
Weiss, Rita Vasconcellos |
author_facet |
Weiss, Rita Vasconcellos Hohl, Alexandre Athayde, Amanda Valéria Luna de Pardini, Dolores Perovano Gomes, Larissa Oliveira, Mônica de Meirelles, Ricardo Martins da Rocha Clapauch, Ruth Spritzer, Poli Mara |
author_role |
author |
author2 |
Hohl, Alexandre Athayde, Amanda Valéria Luna de Pardini, Dolores Perovano Gomes, Larissa Oliveira, Mônica de Meirelles, Ricardo Martins da Rocha Clapauch, Ruth Spritzer, Poli Mara |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Weiss, Rita Vasconcellos Hohl, Alexandre Athayde, Amanda Valéria Luna de Pardini, Dolores Perovano Gomes, Larissa Oliveira, Mônica de Meirelles, Ricardo Martins da Rocha Clapauch, Ruth Spritzer, Poli Mara |
dc.subject.por.fl_str_mv |
Libido Assexualidade Testosterona Feminino |
topic |
Libido Assexualidade Testosterona Feminino Testosterone therapy Female sexual disorder |
dc.subject.eng.fl_str_mv |
Testosterone therapy Female sexual disorder |
description |
Objective: To summarize current evidence regarding testosterone treatment for women with low sexual desire. Materials and methods: The Female Endocrinology and Andrology Department of the Brazilian Society of Endocrinology and Metabolism invited nine experts to review the physiology of testosterone secretion and the use, misuse, and side effects of exogenous testosterone therapy in women, based on the available literature and guidelines and statements from international societies. Results: Low sexual desire is a common complaint in clinical practice, especially in postmenopausal women, and may negatively interfere with quality of life. Testosterone seems to exert a positive effect on sexual desire in women with sexual dysfunction, despite a small magnitude of effect, a lack of long-term safety data, and insufficient evidence to make a broad recommendation for testosterone therapy. Furthermore, there are currently no testosterone formulations approved for women by the relevant regulatory agencies in the United States, Brazil, and most other countries, and testosterone formulations approved for men are not recommended for use by women. Conclusion: Therefore, testosterone therapy might be considered if other strategies fail, but the risks and benefits must be discussed with the patient before prescription. |
publishDate |
2019 |
dc.date.accessioned.fl_str_mv |
2019-10-12T03:55:50Z |
dc.date.issued.fl_str_mv |
2019 |
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info:eu-repo/semantics/article info:eu-repo/semantics/other |
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info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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http://hdl.handle.net/10183/200721 |
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2359-3997 |
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001103781 |
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http://hdl.handle.net/10183/200721 |
dc.language.iso.fl_str_mv |
eng |
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eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Archives of endocrinology and metabolism. São Paulo. Vol. 63, no. 3 (May/June 2019), p. 190-198 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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