Preparation and characterization of hydrogels with potential for use as biomaterials

Detalhes bibliográficos
Autor(a) principal: Thürmer, Monica Beatriz
Data de Publicação: 2014
Outros Autores: Diehl, Carlos Eduardo, Brum, Fábio José Bento, Santos, Luis Alberto dos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/141115
Resumo: Hydrogels have been extensively explored for biomedical applications due to their ability to absorb high water content in its structure, which gives excellent biocompatibility. This work aims at obtaining biocompatible hydrogels with potential for use in increasing the mechanical strength of bone substitutes, or controlled drug release. Poly (N-vinyl-2-pyrrolidone) hydrogels were prepared by free radical polymerization with and without the addition of acrylic acid. Azobisisobutyronitrile and ammonium persulfate were used as initiator and N,N-methylenebisacrylamide was used as the crosslinking agent. The characterization of the hydrogels was performed by thermogravimetric analysis, differential scanning calorimetry, infrared spectroscopy and swelling properties. The results obtained demonstrate different degrees of crosslinking and swelling of up to 490 ± 30%. The different properties of the hydrogels suggest different applications.
id UFRGS-2_e15fe6feed804fb51cc6152e4f329e2d
oai_identifier_str oai:www.lume.ufrgs.br:10183/141115
network_acronym_str UFRGS-2
network_name_str Repositório Institucional da UFRGS
repository_id_str
spelling Thürmer, Monica BeatrizDiehl, Carlos EduardoBrum, Fábio José BentoSantos, Luis Alberto dos2016-05-14T02:08:14Z20141516-1439http://hdl.handle.net/10183/141115000990788Hydrogels have been extensively explored for biomedical applications due to their ability to absorb high water content in its structure, which gives excellent biocompatibility. This work aims at obtaining biocompatible hydrogels with potential for use in increasing the mechanical strength of bone substitutes, or controlled drug release. Poly (N-vinyl-2-pyrrolidone) hydrogels were prepared by free radical polymerization with and without the addition of acrylic acid. Azobisisobutyronitrile and ammonium persulfate were used as initiator and N,N-methylenebisacrylamide was used as the crosslinking agent. The characterization of the hydrogels was performed by thermogravimetric analysis, differential scanning calorimetry, infrared spectroscopy and swelling properties. The results obtained demonstrate different degrees of crosslinking and swelling of up to 490 ± 30%. The different properties of the hydrogels suggest different applications.application/pdfengMaterials research : ibero-american journal of materials. São Carlos. Vol. 17, suppl. 1 (Aug. 2014), p. 109-113HidrogéisBiomedicinaPolímerosBiocompatibleHydrogelPVPPAAPolymerizationPreparation and characterization of hydrogels with potential for use as biomaterialsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL000990788.pdf000990788.pdfTexto completo (inglês)application/pdf1096724http://www.lume.ufrgs.br/bitstream/10183/141115/1/000990788.pdffa1b2e36d3e5ecf373cbe4619795fa68MD51TEXT000990788.pdf.txt000990788.pdf.txtExtracted Texttext/plain22165http://www.lume.ufrgs.br/bitstream/10183/141115/2/000990788.pdf.txt8adac8c729f1a0e71e037f99ea31ab4fMD52THUMBNAIL000990788.pdf.jpg000990788.pdf.jpgGenerated Thumbnailimage/jpeg1888http://www.lume.ufrgs.br/bitstream/10183/141115/3/000990788.pdf.jpgd3afc6ab9b4426f039c5045a8e390a09MD5310183/1411152021-09-18 04:54:09.664494oai:www.lume.ufrgs.br:10183/141115Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-09-18T07:54:09Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Preparation and characterization of hydrogels with potential for use as biomaterials
title Preparation and characterization of hydrogels with potential for use as biomaterials
spellingShingle Preparation and characterization of hydrogels with potential for use as biomaterials
Thürmer, Monica Beatriz
Hidrogéis
Biomedicina
Polímeros
Biocompatible
Hydrogel
PVP
PAA
Polymerization
title_short Preparation and characterization of hydrogels with potential for use as biomaterials
title_full Preparation and characterization of hydrogels with potential for use as biomaterials
title_fullStr Preparation and characterization of hydrogels with potential for use as biomaterials
title_full_unstemmed Preparation and characterization of hydrogels with potential for use as biomaterials
title_sort Preparation and characterization of hydrogels with potential for use as biomaterials
author Thürmer, Monica Beatriz
author_facet Thürmer, Monica Beatriz
Diehl, Carlos Eduardo
Brum, Fábio José Bento
Santos, Luis Alberto dos
author_role author
author2 Diehl, Carlos Eduardo
Brum, Fábio José Bento
Santos, Luis Alberto dos
author2_role author
author
author
dc.contributor.author.fl_str_mv Thürmer, Monica Beatriz
Diehl, Carlos Eduardo
Brum, Fábio José Bento
Santos, Luis Alberto dos
dc.subject.por.fl_str_mv Hidrogéis
Biomedicina
Polímeros
topic Hidrogéis
Biomedicina
Polímeros
Biocompatible
Hydrogel
PVP
PAA
Polymerization
dc.subject.eng.fl_str_mv Biocompatible
Hydrogel
PVP
PAA
Polymerization
description Hydrogels have been extensively explored for biomedical applications due to their ability to absorb high water content in its structure, which gives excellent biocompatibility. This work aims at obtaining biocompatible hydrogels with potential for use in increasing the mechanical strength of bone substitutes, or controlled drug release. Poly (N-vinyl-2-pyrrolidone) hydrogels were prepared by free radical polymerization with and without the addition of acrylic acid. Azobisisobutyronitrile and ammonium persulfate were used as initiator and N,N-methylenebisacrylamide was used as the crosslinking agent. The characterization of the hydrogels was performed by thermogravimetric analysis, differential scanning calorimetry, infrared spectroscopy and swelling properties. The results obtained demonstrate different degrees of crosslinking and swelling of up to 490 ± 30%. The different properties of the hydrogels suggest different applications.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2016-05-14T02:08:14Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/other
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/141115
dc.identifier.issn.pt_BR.fl_str_mv 1516-1439
dc.identifier.nrb.pt_BR.fl_str_mv 000990788
identifier_str_mv 1516-1439
000990788
url http://hdl.handle.net/10183/141115
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Materials research : ibero-american journal of materials. São Carlos. Vol. 17, suppl. 1 (Aug. 2014), p. 109-113
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/141115/1/000990788.pdf
http://www.lume.ufrgs.br/bitstream/10183/141115/2/000990788.pdf.txt
http://www.lume.ufrgs.br/bitstream/10183/141115/3/000990788.pdf.jpg
bitstream.checksum.fl_str_mv fa1b2e36d3e5ecf373cbe4619795fa68
8adac8c729f1a0e71e037f99ea31ab4f
d3afc6ab9b4426f039c5045a8e390a09
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv
_version_ 1801224899614736384

Registros relacionados