Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish

Detalhes bibliográficos
Autor(a) principal: Abreu, Murilo Sander de
Data de Publicação: 2017
Outros Autores: Giacomini, Ana Cristina Vendrametto Varrone, Koakoski, Gessi, Piato, Angelo Luis Stapassoli, Barcellos, Leonardo Jose Gil
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/224250
Resumo: Fluoxetine is a selective serotonin reuptake inhibitor that increases serotonin concentration in the central nervous system and modulates various systems, including the control of sympathetic outflow and the hypothalamus–pituitary– adrenal. However, it is not yet established whether fluoxetine can modulate the responses to stressors stimulants (physical or chemical) that trigger cortisol response in zebrafish. We demonstrate that fluoxetine blunts the response to physical stress, but not to chemical stress.
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spelling Abreu, Murilo Sander deGiacomini, Ana Cristina Vendrametto VarroneKoakoski, GessiPiato, Angelo Luis StapassoliBarcellos, Leonardo Jose Gil2021-07-21T04:23:54Z20172167-8359http://hdl.handle.net/10183/224250001022093Fluoxetine is a selective serotonin reuptake inhibitor that increases serotonin concentration in the central nervous system and modulates various systems, including the control of sympathetic outflow and the hypothalamus–pituitary– adrenal. However, it is not yet established whether fluoxetine can modulate the responses to stressors stimulants (physical or chemical) that trigger cortisol response in zebrafish. We demonstrate that fluoxetine blunts the response to physical stress, but not to chemical stress.application/pdfengPeerJ. Corte Madera. Vol. 5 (2017), e3330, 10 p.FluoxetinaPeixe-zebraHidrocortisonaEstresse fisiológicoCortisolSerotoninSSRIBloodAlarm substanceDivergent effect of fluoxetine on the response to physical or chemical stressors in zebrafishEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001022093.pdf.txt001022093.pdf.txtExtracted Texttext/plain26335http://www.lume.ufrgs.br/bitstream/10183/224250/2/001022093.pdf.txtd5e512e4706bc849e068d06a650f2dbdMD52ORIGINAL001022093.pdfTexto completo (inglês)application/pdf911141http://www.lume.ufrgs.br/bitstream/10183/224250/1/001022093.pdf30a0bf5280ebe9aac5a1b158d35a4122MD5110183/2242502021-08-18 04:36:38.19425oai:www.lume.ufrgs.br:10183/224250Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-08-18T07:36:38Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
title Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
spellingShingle Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
Abreu, Murilo Sander de
Fluoxetina
Peixe-zebra
Hidrocortisona
Estresse fisiológico
Cortisol
Serotonin
SSRI
Blood
Alarm substance
title_short Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
title_full Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
title_fullStr Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
title_full_unstemmed Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
title_sort Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish
author Abreu, Murilo Sander de
author_facet Abreu, Murilo Sander de
Giacomini, Ana Cristina Vendrametto Varrone
Koakoski, Gessi
Piato, Angelo Luis Stapassoli
Barcellos, Leonardo Jose Gil
author_role author
author2 Giacomini, Ana Cristina Vendrametto Varrone
Koakoski, Gessi
Piato, Angelo Luis Stapassoli
Barcellos, Leonardo Jose Gil
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Abreu, Murilo Sander de
Giacomini, Ana Cristina Vendrametto Varrone
Koakoski, Gessi
Piato, Angelo Luis Stapassoli
Barcellos, Leonardo Jose Gil
dc.subject.por.fl_str_mv Fluoxetina
Peixe-zebra
Hidrocortisona
Estresse fisiológico
topic Fluoxetina
Peixe-zebra
Hidrocortisona
Estresse fisiológico
Cortisol
Serotonin
SSRI
Blood
Alarm substance
dc.subject.eng.fl_str_mv Cortisol
Serotonin
SSRI
Blood
Alarm substance
description Fluoxetine is a selective serotonin reuptake inhibitor that increases serotonin concentration in the central nervous system and modulates various systems, including the control of sympathetic outflow and the hypothalamus–pituitary– adrenal. However, it is not yet established whether fluoxetine can modulate the responses to stressors stimulants (physical or chemical) that trigger cortisol response in zebrafish. We demonstrate that fluoxetine blunts the response to physical stress, but not to chemical stress.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2021-07-21T04:23:54Z
dc.type.driver.fl_str_mv Estrangeiro
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/224250
dc.identifier.issn.pt_BR.fl_str_mv 2167-8359
dc.identifier.nrb.pt_BR.fl_str_mv 001022093
identifier_str_mv 2167-8359
001022093
url http://hdl.handle.net/10183/224250
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv PeerJ. Corte Madera. Vol. 5 (2017), e3330, 10 p.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/224250/2/001022093.pdf.txt
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