Behaviour of the foramen ovale flow in fetuses with intrauterine growth restriction

• Autor(a) principal: Nader, Angela Rodrigues Leston
• Data de Publicação: 2018
• Outros Autores: Zielinsky, Paulo, Naujorks, Alexandre Antonio, Nicoloso, Luiz Henrique Soares, Piccoli Junior, Antônio Luiz, Sulis, Natássia Miranda, Van der Sand, Luiza Ferreira, Marinho, Gabriela dos Santos, Santos, Fernanda Greinert dos, Gosmann, Natan Pereira, Becker Junior, Eduardo, Frajndlich, Renato, Beherens, Tamara, Silva, Marcelo Brandao da, Barbisan, Carolina Weiss, Busato, Stefano Boemler, Lopes, Mauro, Klein, Caroline Cardoso
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/180830
• topic: Forame oval; Gravidez; Estudos transversais; Retardo do crescimento fetal

Foramen ovale (FO) flow may be altered in IUGR. .is study was designed to test this hypothesis. Methods. Forty pregnant women (24–38 weeks) were divided into 3 groups: group I (IUGR), group II (adequate growth and maternal hypertension), and group III (normal controls). Impedance across the FO was assessed by the FO pulsatility index (FOPI): (systolic velocity − presystolic velocity)/mean velocity. Statistical analysis utilized ANOVA, Tukey test, and ROC curves. Results. Mean FOPI in IUGR fetuses (n=15) was 3.70 ± 0.99 (3.15–4.26); in the group II (n=12), it was 2.84 ± 0.69 (2.40–3.28), and in the group III (n=13), it was 2.77 ± 0.44 (2.50–3.04) (p=0.004). FOPI and UtA RI were correlated (r= 0.375, p= 0.017), as well as FOPI and UA RI (r= 0.356, p= 0.024) and, inversely, FOPI and MCA RI (r= −0.359, p= 0.023). Conclusions. .e FO flow pulsatility index is increased in fetuses with IUGR, probably as a result of impaired left ventricular diastolic function