Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/220491 |
Resumo: | Candida spp. infections, also called candidiasis or candidosis, vary from mild to invasive and even can be fatal, being oral candidiasis one of the most common fungal infections in humans. Several systemic and local factors can stimulate the development of infections in the oral mucosa. The main treatment for oral candidiasis is the use of antifungals and the nystatin has been the first choice overall. However, with the increase in resistance of Candida species by the antifungals used in clinical practice, including the risk of toxicity associated with their use, there is an increase to the interest in researching antifungal activity in natural components. The aim of this study is to evaluate the antifungal activity of essential oils of Citrus limonum, Eucalyptus globulus, Eucalyptus citriodora, Mentha Piperita and Rosmarinus officinalis in isolated Candida spp. of the patient's oral cavity by disk diffusion test and minimum inhibitory concentration (MIC) determination. The essential oil of E. globulus showed the best result in the disc diffusion method, with inhibition zone ranging from 33mm to 65mm. The essential oils of E. globulus and M. piperita showed antifungal activity, the MIC values obtained with the essential oil of E. globulus ranged from 125 µg/mL to >1000 µg/mL and the MIC values obtained with the essential oil of M. piperita ranged 250 µg/mL to >1000 µg/mL. |
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Mezzomo, LeticiaFerrao, Simone KrauseButzge, Juliana CarolineCalil, Luciane NoalApel, Miriam AndersLuisi, Simone BonatoLimberger, Renata PereiraMezzari, Adelina2021-05-04T04:27:44Z20212349-2759http://hdl.handle.net/10183/220491001124448Candida spp. infections, also called candidiasis or candidosis, vary from mild to invasive and even can be fatal, being oral candidiasis one of the most common fungal infections in humans. Several systemic and local factors can stimulate the development of infections in the oral mucosa. The main treatment for oral candidiasis is the use of antifungals and the nystatin has been the first choice overall. However, with the increase in resistance of Candida species by the antifungals used in clinical practice, including the risk of toxicity associated with their use, there is an increase to the interest in researching antifungal activity in natural components. The aim of this study is to evaluate the antifungal activity of essential oils of Citrus limonum, Eucalyptus globulus, Eucalyptus citriodora, Mentha Piperita and Rosmarinus officinalis in isolated Candida spp. of the patient's oral cavity by disk diffusion test and minimum inhibitory concentration (MIC) determination. The essential oil of E. globulus showed the best result in the disc diffusion method, with inhibition zone ranging from 33mm to 65mm. The essential oils of E. globulus and M. piperita showed antifungal activity, the MIC values obtained with the essential oil of E. globulus ranged from 125 µg/mL to >1000 µg/mL and the MIC values obtained with the essential oil of M. piperita ranged 250 µg/mL to >1000 µg/mL.application/pdfengJournal of Innovations in Pharmaceutical and Biological Sciences. Aurangabad. Vol. 8, no. 2 (Apr./June 2021), p. 1–9Candidíase bucalCandidaTestes de sensibilidade microbianaAntifúngicos : ToxicidadeÓleos voláteisCandida spp.Essential oilEvaluation of antifungal activity of essential oils against different Candida spp. clinical isolatesEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001124448.pdf.txt001124448.pdf.txtExtracted Texttext/plain40445http://www.lume.ufrgs.br/bitstream/10183/220491/2/001124448.pdf.txt4c455877f87eddf7d9b4cfabdaf86e2cMD52ORIGINAL001124448.pdfTexto completo (inglês)application/pdf925002http://www.lume.ufrgs.br/bitstream/10183/220491/1/001124448.pdf0bfdf5d8e77d025d7d94018e74a50c8dMD5110183/2204912021-05-07 04:40:56.020508oai:www.lume.ufrgs.br:10183/220491Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-05-07T07:40:56Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
title |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
spellingShingle |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates Mezzomo, Leticia Candidíase bucal Candida Testes de sensibilidade microbiana Antifúngicos : Toxicidade Óleos voláteis Candida spp. Essential oil |
title_short |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
title_full |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
title_fullStr |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
title_full_unstemmed |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
title_sort |
Evaluation of antifungal activity of essential oils against different Candida spp. clinical isolates |
author |
Mezzomo, Leticia |
author_facet |
Mezzomo, Leticia Ferrao, Simone Krause Butzge, Juliana Caroline Calil, Luciane Noal Apel, Miriam Anders Luisi, Simone Bonato Limberger, Renata Pereira Mezzari, Adelina |
author_role |
author |
author2 |
Ferrao, Simone Krause Butzge, Juliana Caroline Calil, Luciane Noal Apel, Miriam Anders Luisi, Simone Bonato Limberger, Renata Pereira Mezzari, Adelina |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Mezzomo, Leticia Ferrao, Simone Krause Butzge, Juliana Caroline Calil, Luciane Noal Apel, Miriam Anders Luisi, Simone Bonato Limberger, Renata Pereira Mezzari, Adelina |
dc.subject.por.fl_str_mv |
Candidíase bucal Candida Testes de sensibilidade microbiana Antifúngicos : Toxicidade Óleos voláteis |
topic |
Candidíase bucal Candida Testes de sensibilidade microbiana Antifúngicos : Toxicidade Óleos voláteis Candida spp. Essential oil |
dc.subject.eng.fl_str_mv |
Candida spp. Essential oil |
description |
Candida spp. infections, also called candidiasis or candidosis, vary from mild to invasive and even can be fatal, being oral candidiasis one of the most common fungal infections in humans. Several systemic and local factors can stimulate the development of infections in the oral mucosa. The main treatment for oral candidiasis is the use of antifungals and the nystatin has been the first choice overall. However, with the increase in resistance of Candida species by the antifungals used in clinical practice, including the risk of toxicity associated with their use, there is an increase to the interest in researching antifungal activity in natural components. The aim of this study is to evaluate the antifungal activity of essential oils of Citrus limonum, Eucalyptus globulus, Eucalyptus citriodora, Mentha Piperita and Rosmarinus officinalis in isolated Candida spp. of the patient's oral cavity by disk diffusion test and minimum inhibitory concentration (MIC) determination. The essential oil of E. globulus showed the best result in the disc diffusion method, with inhibition zone ranging from 33mm to 65mm. The essential oils of E. globulus and M. piperita showed antifungal activity, the MIC values obtained with the essential oil of E. globulus ranged from 125 µg/mL to >1000 µg/mL and the MIC values obtained with the essential oil of M. piperita ranged 250 µg/mL to >1000 µg/mL. |
publishDate |
2021 |
dc.date.accessioned.fl_str_mv |
2021-05-04T04:27:44Z |
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2021 |
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http://hdl.handle.net/10183/220491 |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Journal of Innovations in Pharmaceutical and Biological Sciences. Aurangabad. Vol. 8, no. 2 (Apr./June 2021), p. 1–9 |
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