Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/179667 |
Resumo: | This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders. |
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Hirsch, Mauro MozaelDeckmann, IohannaSilva, Mellanie Fontes Dutra daNegrini, Guilherme BauerNunes, Gustavo Della FloraNunes, Walquiria SouzaRabelo, Bruna FrizzoRiesgo, Rudimar dos SantosMargis, RogerioBambini Júnior, VictorioGottfried, Carmem Juracy Silveira2018-06-22T02:29:45Z20182352-3409http://hdl.handle.net/10183/179667001069644This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.application/pdfengData in brief. [Amsterdam], Elsevier. Vol. 18, (Jun. 2018), p. 1433-1440Transtorno autísticoPreferências alimentaresMicroRNAsResveratrolPesquisa médica translacionalÁcido valpróicoAutismSocial transmission of food preferenceMicroRNA ResveratrolResveratrolTranslational researchPreclinical modelsValproateData on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNAEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001069644.pdf001069644.pdfTexto completo (inglês)application/pdf664789http://www.lume.ufrgs.br/bitstream/10183/179667/1/001069644.pdff516f891b6bc8234dc6de13a8e18a178MD51TEXT001069644.pdf.txt001069644.pdf.txtExtracted Texttext/plain22574http://www.lume.ufrgs.br/bitstream/10183/179667/2/001069644.pdf.txtccd2d608ea0168ebf2433ca36d3a1054MD5210183/1796672021-06-26 04:40:10.075096oai:www.lume.ufrgs.br:10183/179667Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-06-26T07:40:10Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
title |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
spellingShingle |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA Hirsch, Mauro Mozael Transtorno autístico Preferências alimentares MicroRNAs Resveratrol Pesquisa médica translacional Ácido valpróico Autism Social transmission of food preference MicroRNA Resveratrol Resveratrol Translational research Preclinical models Valproate |
title_short |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
title_full |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
title_fullStr |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
title_full_unstemmed |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
title_sort |
Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA |
author |
Hirsch, Mauro Mozael |
author_facet |
Hirsch, Mauro Mozael Deckmann, Iohanna Silva, Mellanie Fontes Dutra da Negrini, Guilherme Bauer Nunes, Gustavo Della Flora Nunes, Walquiria Souza Rabelo, Bruna Frizzo Riesgo, Rudimar dos Santos Margis, Rogerio Bambini Júnior, Victorio Gottfried, Carmem Juracy Silveira |
author_role |
author |
author2 |
Deckmann, Iohanna Silva, Mellanie Fontes Dutra da Negrini, Guilherme Bauer Nunes, Gustavo Della Flora Nunes, Walquiria Souza Rabelo, Bruna Frizzo Riesgo, Rudimar dos Santos Margis, Rogerio Bambini Júnior, Victorio Gottfried, Carmem Juracy Silveira |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Hirsch, Mauro Mozael Deckmann, Iohanna Silva, Mellanie Fontes Dutra da Negrini, Guilherme Bauer Nunes, Gustavo Della Flora Nunes, Walquiria Souza Rabelo, Bruna Frizzo Riesgo, Rudimar dos Santos Margis, Rogerio Bambini Júnior, Victorio Gottfried, Carmem Juracy Silveira |
dc.subject.por.fl_str_mv |
Transtorno autístico Preferências alimentares MicroRNAs Resveratrol Pesquisa médica translacional Ácido valpróico |
topic |
Transtorno autístico Preferências alimentares MicroRNAs Resveratrol Pesquisa médica translacional Ácido valpróico Autism Social transmission of food preference MicroRNA Resveratrol Resveratrol Translational research Preclinical models Valproate |
dc.subject.eng.fl_str_mv |
Autism Social transmission of food preference MicroRNA Resveratrol Resveratrol Translational research Preclinical models Valproate |
description |
This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-06-22T02:29:45Z |
dc.date.issued.fl_str_mv |
2018 |
dc.type.driver.fl_str_mv |
Estrangeiro info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/179667 |
dc.identifier.issn.pt_BR.fl_str_mv |
2352-3409 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001069644 |
identifier_str_mv |
2352-3409 001069644 |
url |
http://hdl.handle.net/10183/179667 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
Data in brief. [Amsterdam], Elsevier. Vol. 18, (Jun. 2018), p. 1433-1440 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFRGS instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
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Universidade Federal do Rio Grande do Sul (UFRGS) |
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UFRGS |
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UFRGS |
reponame_str |
Repositório Institucional da UFRGS |
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Repositório Institucional da UFRGS |
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http://www.lume.ufrgs.br/bitstream/10183/179667/1/001069644.pdf http://www.lume.ufrgs.br/bitstream/10183/179667/2/001069644.pdf.txt |
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