Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA

Detalhes bibliográficos
Autor(a) principal: Hirsch, Mauro Mozael
Data de Publicação: 2018
Outros Autores: Deckmann, Iohanna, Silva, Mellanie Fontes Dutra da, Negrini, Guilherme Bauer, Nunes, Gustavo Della Flora, Nunes, Walquiria Souza, Rabelo, Bruna Frizzo, Riesgo, Rudimar dos Santos, Margis, Rogerio, Bambini Júnior, Victorio, Gottfried, Carmem Juracy Silveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRGS
Texto Completo: http://hdl.handle.net/10183/179667
Resumo: This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.
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spelling Hirsch, Mauro MozaelDeckmann, IohannaSilva, Mellanie Fontes Dutra daNegrini, Guilherme BauerNunes, Gustavo Della FloraNunes, Walquiria SouzaRabelo, Bruna FrizzoRiesgo, Rudimar dos SantosMargis, RogerioBambini Júnior, VictorioGottfried, Carmem Juracy Silveira2018-06-22T02:29:45Z20182352-3409http://hdl.handle.net/10183/179667001069644This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.application/pdfengData in brief. [Amsterdam], Elsevier. Vol. 18, (Jun. 2018), p. 1433-1440Transtorno autísticoPreferências alimentaresMicroRNAsResveratrolPesquisa médica translacionalÁcido valpróicoAutismSocial transmission of food preferenceMicroRNA ResveratrolResveratrolTranslational researchPreclinical modelsValproateData on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNAEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001069644.pdf001069644.pdfTexto completo (inglês)application/pdf664789http://www.lume.ufrgs.br/bitstream/10183/179667/1/001069644.pdff516f891b6bc8234dc6de13a8e18a178MD51TEXT001069644.pdf.txt001069644.pdf.txtExtracted Texttext/plain22574http://www.lume.ufrgs.br/bitstream/10183/179667/2/001069644.pdf.txtccd2d608ea0168ebf2433ca36d3a1054MD5210183/1796672021-06-26 04:40:10.075096oai:www.lume.ufrgs.br:10183/179667Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2021-06-26T07:40:10Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
title Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
spellingShingle Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
Hirsch, Mauro Mozael
Transtorno autístico
Preferências alimentares
MicroRNAs
Resveratrol
Pesquisa médica translacional
Ácido valpróico
Autism
Social transmission of food preference
MicroRNA Resveratrol
Resveratrol
Translational research
Preclinical models
Valproate
title_short Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
title_full Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
title_fullStr Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
title_full_unstemmed Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
title_sort Data on social transmission of food preference in a model of autism induced by valproic acid and translational analysis of circulating microRNA
author Hirsch, Mauro Mozael
author_facet Hirsch, Mauro Mozael
Deckmann, Iohanna
Silva, Mellanie Fontes Dutra da
Negrini, Guilherme Bauer
Nunes, Gustavo Della Flora
Nunes, Walquiria Souza
Rabelo, Bruna Frizzo
Riesgo, Rudimar dos Santos
Margis, Rogerio
Bambini Júnior, Victorio
Gottfried, Carmem Juracy Silveira
author_role author
author2 Deckmann, Iohanna
Silva, Mellanie Fontes Dutra da
Negrini, Guilherme Bauer
Nunes, Gustavo Della Flora
Nunes, Walquiria Souza
Rabelo, Bruna Frizzo
Riesgo, Rudimar dos Santos
Margis, Rogerio
Bambini Júnior, Victorio
Gottfried, Carmem Juracy Silveira
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Hirsch, Mauro Mozael
Deckmann, Iohanna
Silva, Mellanie Fontes Dutra da
Negrini, Guilherme Bauer
Nunes, Gustavo Della Flora
Nunes, Walquiria Souza
Rabelo, Bruna Frizzo
Riesgo, Rudimar dos Santos
Margis, Rogerio
Bambini Júnior, Victorio
Gottfried, Carmem Juracy Silveira
dc.subject.por.fl_str_mv Transtorno autístico
Preferências alimentares
MicroRNAs
Resveratrol
Pesquisa médica translacional
Ácido valpróico
topic Transtorno autístico
Preferências alimentares
MicroRNAs
Resveratrol
Pesquisa médica translacional
Ácido valpróico
Autism
Social transmission of food preference
MicroRNA Resveratrol
Resveratrol
Translational research
Preclinical models
Valproate
dc.subject.eng.fl_str_mv Autism
Social transmission of food preference
MicroRNA Resveratrol
Resveratrol
Translational research
Preclinical models
Valproate
description This article contains data of Social Transmission of Food Preference in an animal model of autism and the evaluation of a set of microRNA analyzed in autistic patients and animal model of autism. The analyses of the absolute consumption of two flavored food by male rats prenatally exposed to valproic acid (VPA) and treated with resveratrol (RSV), showed that VPA animals show a trend to eat less of the flavored food presented by a demonstrator rat. We also identified 13 microRNA with similar levels among rodents’ experimental groups, as well as 11 microRNA with no alterations between autistic and control subjects. Further evaluation of mechanisms of VPA and RSV actions on behavioral and molecular alterations can shed light in important biomarkers and etiological triggers of autistic spectrum disorders.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-06-22T02:29:45Z
dc.date.issued.fl_str_mv 2018
dc.type.driver.fl_str_mv Estrangeiro
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/179667
dc.identifier.issn.pt_BR.fl_str_mv 2352-3409
dc.identifier.nrb.pt_BR.fl_str_mv 001069644
identifier_str_mv 2352-3409
001069644
url http://hdl.handle.net/10183/179667
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Data in brief. [Amsterdam], Elsevier. Vol. 18, (Jun. 2018), p. 1433-1440
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
bitstream.url.fl_str_mv http://www.lume.ufrgs.br/bitstream/10183/179667/1/001069644.pdf
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