Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/185282 |
Resumo: | The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians,especially due to the low sensitivity and long turnaround time of the classic diagnostic meth-ods. In recent years, studies involving a variety of non-culture-based diagnostic tests havebeen published in the literature. We performed a systematic review by selecting studies eval-uating non-culture-based diagnostic methods for progressive disseminated histoplasmosis.We searched for articles evaluating detection of antibody, antigens, as well as DNA-baseddiagnostic methods. A comprehensive PUBMED, Web of Science, and Cochrane Librarysearch was performed between the years 1956 and 2016. Case reports, review articles, non-human models and series involving less than 10 patients were excluded. We found 278articles and after initial review 18 articles were included: (12) involved antigen detectionmethods, (4) molecular methods, and (2) antibody detection methods. Here we demonstratethat the pursuit of new technologies is ultimately required for the early and accurate diag-nosis of disseminated histoplasmosis. In particular, urinary antigen detection was the mostaccurate tool when compared with other diagnostic techniques. |
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Falci, Diego RodriguesHoffmann, Elias da RosaPaskulin, Diego D'ÁvilaPasqualotto, Alessandro Comaru2018-11-30T02:42:50Z20171413-8670http://hdl.handle.net/10183/185282001080457The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians,especially due to the low sensitivity and long turnaround time of the classic diagnostic meth-ods. In recent years, studies involving a variety of non-culture-based diagnostic tests havebeen published in the literature. We performed a systematic review by selecting studies eval-uating non-culture-based diagnostic methods for progressive disseminated histoplasmosis.We searched for articles evaluating detection of antibody, antigens, as well as DNA-baseddiagnostic methods. A comprehensive PUBMED, Web of Science, and Cochrane Librarysearch was performed between the years 1956 and 2016. Case reports, review articles, non-human models and series involving less than 10 patients were excluded. We found 278articles and after initial review 18 articles were included: (12) involved antigen detectionmethods, (4) molecular methods, and (2) antibody detection methods. Here we demonstratethat the pursuit of new technologies is ultimately required for the early and accurate diag-nosis of disseminated histoplasmosis. In particular, urinary antigen detection was the mostaccurate tool when compared with other diagnostic techniques.application/pdfengThe Brazilian journal of infectious diseases. Salvador. Vol. 21, n. 1 (Jan.-Feb. 2017), p. 7-11HistoplasmoseDiagnósticoTécnicas imunoenzimáticasReação em cadeia da polimeraseMétodosSensibilidade e especificidadeTestes sorológicosDisseminated histoplasmosisNon-cultureEnzyme immunoassayDiagnostic testsaProgressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic testsinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001080457.pdf.txt001080457.pdf.txtExtracted Texttext/plain25567http://www.lume.ufrgs.br/bitstream/10183/185282/2/001080457.pdf.txtab682d6cf2583de9a13f2331c74d881aMD52ORIGINAL001080457.pdfTexto completo (inglês)application/pdf570805http://www.lume.ufrgs.br/bitstream/10183/185282/1/001080457.pdfe38ccd0009524e46ecead73c10abcbd2MD5110183/1852822019-10-04 03:48:08.535196oai:www.lume.ufrgs.br:10183/185282Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2019-10-04T06:48:08Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
title |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
spellingShingle |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests Falci, Diego Rodrigues Histoplasmose Diagnóstico Técnicas imunoenzimáticas Reação em cadeia da polimerase Métodos Sensibilidade e especificidade Testes sorológicos Disseminated histoplasmosis Non-culture Enzyme immunoassay Diagnostic testsa |
title_short |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
title_full |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
title_fullStr |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
title_full_unstemmed |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
title_sort |
Progressive disseminated histoplasmosis : a systematic review on the performance of non-culture-based diagnostic tests |
author |
Falci, Diego Rodrigues |
author_facet |
Falci, Diego Rodrigues Hoffmann, Elias da Rosa Paskulin, Diego D'Ávila Pasqualotto, Alessandro Comaru |
author_role |
author |
author2 |
Hoffmann, Elias da Rosa Paskulin, Diego D'Ávila Pasqualotto, Alessandro Comaru |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Falci, Diego Rodrigues Hoffmann, Elias da Rosa Paskulin, Diego D'Ávila Pasqualotto, Alessandro Comaru |
dc.subject.por.fl_str_mv |
Histoplasmose Diagnóstico Técnicas imunoenzimáticas Reação em cadeia da polimerase Métodos Sensibilidade e especificidade Testes sorológicos |
topic |
Histoplasmose Diagnóstico Técnicas imunoenzimáticas Reação em cadeia da polimerase Métodos Sensibilidade e especificidade Testes sorológicos Disseminated histoplasmosis Non-culture Enzyme immunoassay Diagnostic testsa |
dc.subject.eng.fl_str_mv |
Disseminated histoplasmosis Non-culture Enzyme immunoassay Diagnostic testsa |
description |
The diagnosis of progressive disseminated histoplasmosis is often a challenge to clinicians,especially due to the low sensitivity and long turnaround time of the classic diagnostic meth-ods. In recent years, studies involving a variety of non-culture-based diagnostic tests havebeen published in the literature. We performed a systematic review by selecting studies eval-uating non-culture-based diagnostic methods for progressive disseminated histoplasmosis.We searched for articles evaluating detection of antibody, antigens, as well as DNA-baseddiagnostic methods. A comprehensive PUBMED, Web of Science, and Cochrane Librarysearch was performed between the years 1956 and 2016. Case reports, review articles, non-human models and series involving less than 10 patients were excluded. We found 278articles and after initial review 18 articles were included: (12) involved antigen detectionmethods, (4) molecular methods, and (2) antibody detection methods. Here we demonstratethat the pursuit of new technologies is ultimately required for the early and accurate diag-nosis of disseminated histoplasmosis. In particular, urinary antigen detection was the mostaccurate tool when compared with other diagnostic techniques. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2018-11-30T02:42:50Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/other |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10183/185282 |
dc.identifier.issn.pt_BR.fl_str_mv |
1413-8670 |
dc.identifier.nrb.pt_BR.fl_str_mv |
001080457 |
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1413-8670 001080457 |
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http://hdl.handle.net/10183/185282 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.pt_BR.fl_str_mv |
The Brazilian journal of infectious diseases. Salvador. Vol. 21, n. 1 (Jan.-Feb. 2017), p. 7-11 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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UFRGS |
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Repositório Institucional da UFRGS |
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Repositório Institucional da UFRGS |
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