Benzodiazepines utilization in Brazilian older adults : a population-based study

• Autor(a) principal: Freire, Marina de Borba Oliveira
• Data de Publicação: 2022
• Outros Autores: Silva, Bruna Gonçalves Cordeiro da, Bertoldi, Andréa Dâmaso, Fontanella, Andréia Turmina, Mengue, Sotero Serrate, Ramos, Luiz Roberto, Tavares, Noemia Urruth Leão, Dal Pizzol, Tatiane da Silva, Arrais, Paulo Sérgio Dourado, Farias, Mareni Rocha, Luiza, Vera Lúcia, Oliveira, Maria Auxiliadora, Menezes, Ana Maria Baptista
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRGS
• Texto Completo: http://hdl.handle.net/10183/249545
• topic: Benzodiazepinas : Uso terapêutico : Idosos; Uso de medicamentos : Brasil; Estudos transversais; Aged; Drug utilization; Benzodiazepines; Risk factors; Cross-sectional studies

OBJECTIVE: To evaluate the utilization of benzodiazepines (BZD) in Brazilian older adults, based on the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey of Access, Use and Promotion of Rational Use of Medicines). METHODS: The PNAUM is a cross-sectional study conducted between 2013 and 2014, representing the Brazilian urban population. In the present study, we included 60 years or older (n = 9,019) individuals. We calculated the prevalence of BZD utilization in the 15 days prior to survey data collection according to independent variables, using a hierarchical Poisson regression model. A semistructured interview performed empirical data collection (household interview). RESULTS: The prevalence of BZD utilization in the older adults was 9.3% (95%CI: 8.3–10.4). After adjustments, BZD utilization was associated with female sex (PR = 1.88; 95%CI: 1.52–2.32), depression (PR = 5.31; 95%CI: 4.41–6, 38), multimorbidity (PR = 1.44; 95%CI: 1.20–1.73), emergency room visit or hospitalization in the last 12 months (PR = 1.42; 95%CI: 1.18–1.70 ), polypharmacy (PR = 1.26; 95%CI: 1.01–1.57) and poor or very poor self-rated health (PR = 4.16; 95%CI: 2.10–8.22). Utilization was lower in the North region (PR = 0.18; 95%CI: 0.13–0.27) and in individuals who reported abusive alcohol consumption in the last month (PR = 0.42; 95%CI: 0.19–0.94). CONCLUSION: Despite contraindications, results showed a high prevalence of BZD utilization in older adults, particularly in those with depression, and wide regional and sex differences.