Benzodiazepines utilization in Brazilian older adults: a population-based study

Detalhes bibliográficos
Autor(a) principal: Freire,Marina de Borba Oliveira
Data de Publicação: 2022
Outros Autores: Da Silva,Bruna Gonçalves Cordeiro, Bertoldi,Andréa Dâmaso, Fontanella,Andréia Turmina, Mengue,Sotero Serrate, Ramos,Luiz Roberto, Tavares,Noemia Urruth Leão, Pizzol,Tatiane da Silva Dal, Arrais,Paulo Sérgio Dourado, Farias,Mareni Rocha, Luiza,Vera Lucia, Oliveira,Maria Auxiliadora, Menezes,Ana Maria Baptista
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Revista de Saúde Pública
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100208
Resumo: ABSTRACT OBJECTIVE To evaluate the utilization of benzodiazepines (BZD) in Brazilian older adults, based on the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey of Access, Use and Promotion of Rational Use of Medicines). METHODS The PNAUM is a cross-sectional study conducted between 2013 and 2014, representing the Brazilian urban population. In the present study, we included 60 years or older (n = 9,019) individuals. We calculated the prevalence of BZD utilization in the 15 days prior to survey data collection according to independent variables, using a hierarchical Poisson regression model. A semistructured interview performed empirical data collection (household interview). RESULTS The prevalence of BZD utilization in the older adults was 9.3% (95%CI: 8.3–10.4). After adjustments, BZD utilization was associated with female sex (PR = 1.88; 95%CI: 1.52–2.32), depression (PR = 5.31; 95%CI: 4.41–6, 38), multimorbidity (PR = 1.44; 95%CI: 1.20–1.73), emergency room visit or hospitalization in the last 12 months (PR = 1.42; 95%CI: 1.18–1.70 ), polypharmacy (PR = 1.26; 95%CI: 1.01–1.57) and poor or very poor self-rated health (PR = 4.16; 95%CI: 2.10–8.22). Utilization was lower in the North region (PR = 0.18; 95%CI: 0.13–0.27) and in individuals who reported abusive alcohol consumption in the last month (PR = 0.42; 95%CI: 0.19–0.94). CONCLUSION Despite contraindications, results showed a high prevalence of BZD utilization in older adults, particularly in those with depression, and wide regional and sex differences.
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spelling Benzodiazepines utilization in Brazilian older adults: a population-based studyAgedDrug UtilizationBenzodiazepinesRisk FactorsCross-Sectional StudiesABSTRACT OBJECTIVE To evaluate the utilization of benzodiazepines (BZD) in Brazilian older adults, based on the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey of Access, Use and Promotion of Rational Use of Medicines). METHODS The PNAUM is a cross-sectional study conducted between 2013 and 2014, representing the Brazilian urban population. In the present study, we included 60 years or older (n = 9,019) individuals. We calculated the prevalence of BZD utilization in the 15 days prior to survey data collection according to independent variables, using a hierarchical Poisson regression model. A semistructured interview performed empirical data collection (household interview). RESULTS The prevalence of BZD utilization in the older adults was 9.3% (95%CI: 8.3–10.4). After adjustments, BZD utilization was associated with female sex (PR = 1.88; 95%CI: 1.52–2.32), depression (PR = 5.31; 95%CI: 4.41–6, 38), multimorbidity (PR = 1.44; 95%CI: 1.20–1.73), emergency room visit or hospitalization in the last 12 months (PR = 1.42; 95%CI: 1.18–1.70 ), polypharmacy (PR = 1.26; 95%CI: 1.01–1.57) and poor or very poor self-rated health (PR = 4.16; 95%CI: 2.10–8.22). Utilization was lower in the North region (PR = 0.18; 95%CI: 0.13–0.27) and in individuals who reported abusive alcohol consumption in the last month (PR = 0.42; 95%CI: 0.19–0.94). CONCLUSION Despite contraindications, results showed a high prevalence of BZD utilization in older adults, particularly in those with depression, and wide regional and sex differences.Faculdade de Saúde Pública da Universidade de São Paulo2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100208Revista de Saúde Pública v.56 2022reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USP10.11606/s1518-8787.2022056003740info:eu-repo/semantics/openAccessFreire,Marina de Borba OliveiraDa Silva,Bruna Gonçalves CordeiroBertoldi,Andréa DâmasoFontanella,Andréia TurminaMengue,Sotero SerrateRamos,Luiz RobertoTavares,Noemia Urruth LeãoPizzol,Tatiane da Silva DalArrais,Paulo Sérgio DouradoFarias,Mareni RochaLuiza,Vera LuciaOliveira,Maria AuxiliadoraMenezes,Ana Maria Baptistaeng2022-03-17T00:00:00Zoai:scielo:S0034-89102022000100208Revistahttp://www.scielo.br/scielo.php?script=sci_serial&pid=0034-8910&lng=pt&nrm=isoONGhttps://old.scielo.br/oai/scielo-oai.phprevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2022-03-17T00:00Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Benzodiazepines utilization in Brazilian older adults: a population-based study
title Benzodiazepines utilization in Brazilian older adults: a population-based study
spellingShingle Benzodiazepines utilization in Brazilian older adults: a population-based study
Freire,Marina de Borba Oliveira
Aged
Drug Utilization
Benzodiazepines
Risk Factors
Cross-Sectional Studies
title_short Benzodiazepines utilization in Brazilian older adults: a population-based study
title_full Benzodiazepines utilization in Brazilian older adults: a population-based study
title_fullStr Benzodiazepines utilization in Brazilian older adults: a population-based study
title_full_unstemmed Benzodiazepines utilization in Brazilian older adults: a population-based study
title_sort Benzodiazepines utilization in Brazilian older adults: a population-based study
author Freire,Marina de Borba Oliveira
author_facet Freire,Marina de Borba Oliveira
Da Silva,Bruna Gonçalves Cordeiro
Bertoldi,Andréa Dâmaso
Fontanella,Andréia Turmina
Mengue,Sotero Serrate
Ramos,Luiz Roberto
Tavares,Noemia Urruth Leão
Pizzol,Tatiane da Silva Dal
Arrais,Paulo Sérgio Dourado
Farias,Mareni Rocha
Luiza,Vera Lucia
Oliveira,Maria Auxiliadora
Menezes,Ana Maria Baptista
author_role author
author2 Da Silva,Bruna Gonçalves Cordeiro
Bertoldi,Andréa Dâmaso
Fontanella,Andréia Turmina
Mengue,Sotero Serrate
Ramos,Luiz Roberto
Tavares,Noemia Urruth Leão
Pizzol,Tatiane da Silva Dal
Arrais,Paulo Sérgio Dourado
Farias,Mareni Rocha
Luiza,Vera Lucia
Oliveira,Maria Auxiliadora
Menezes,Ana Maria Baptista
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freire,Marina de Borba Oliveira
Da Silva,Bruna Gonçalves Cordeiro
Bertoldi,Andréa Dâmaso
Fontanella,Andréia Turmina
Mengue,Sotero Serrate
Ramos,Luiz Roberto
Tavares,Noemia Urruth Leão
Pizzol,Tatiane da Silva Dal
Arrais,Paulo Sérgio Dourado
Farias,Mareni Rocha
Luiza,Vera Lucia
Oliveira,Maria Auxiliadora
Menezes,Ana Maria Baptista
dc.subject.por.fl_str_mv Aged
Drug Utilization
Benzodiazepines
Risk Factors
Cross-Sectional Studies
topic Aged
Drug Utilization
Benzodiazepines
Risk Factors
Cross-Sectional Studies
description ABSTRACT OBJECTIVE To evaluate the utilization of benzodiazepines (BZD) in Brazilian older adults, based on the Pesquisa Nacional de Acesso, Utilização e Promoção do Uso Racional de Medicamentos (PNAUM - National Survey of Access, Use and Promotion of Rational Use of Medicines). METHODS The PNAUM is a cross-sectional study conducted between 2013 and 2014, representing the Brazilian urban population. In the present study, we included 60 years or older (n = 9,019) individuals. We calculated the prevalence of BZD utilization in the 15 days prior to survey data collection according to independent variables, using a hierarchical Poisson regression model. A semistructured interview performed empirical data collection (household interview). RESULTS The prevalence of BZD utilization in the older adults was 9.3% (95%CI: 8.3–10.4). After adjustments, BZD utilization was associated with female sex (PR = 1.88; 95%CI: 1.52–2.32), depression (PR = 5.31; 95%CI: 4.41–6, 38), multimorbidity (PR = 1.44; 95%CI: 1.20–1.73), emergency room visit or hospitalization in the last 12 months (PR = 1.42; 95%CI: 1.18–1.70 ), polypharmacy (PR = 1.26; 95%CI: 1.01–1.57) and poor or very poor self-rated health (PR = 4.16; 95%CI: 2.10–8.22). Utilization was lower in the North region (PR = 0.18; 95%CI: 0.13–0.27) and in individuals who reported abusive alcohol consumption in the last month (PR = 0.42; 95%CI: 0.19–0.94). CONCLUSION Despite contraindications, results showed a high prevalence of BZD utilization in older adults, particularly in those with depression, and wide regional and sex differences.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100208
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-89102022000100208
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.11606/s1518-8787.2022056003740
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
publisher.none.fl_str_mv Faculdade de Saúde Pública da Universidade de São Paulo
dc.source.none.fl_str_mv Revista de Saúde Pública v.56 2022
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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