Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal Brasileiro de Psiquiatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045 |
Resumo: | ABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (<57.5; 80/66), MD and controls = 0.98 (<50; 100/96), MCI and MD = 0.86 (<49.5; 100/74). Conclusions: ACE-R and Mini-Mental State Examination (MMSE) scores for older adults with MCI and controls were significantly lower than those reported in similar studies. These preliminary findings support the need for establishing reliable cut-off scores for cognitive assessment of older Brazilian adults with low schooling at risk for dementia taking into consideration ecological and local variables. |
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Jornal Brasileiro de Psiquiatria (Online) |
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Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational levelDementiacognitive screeningilliterateNortheastAddenbrookeaccuracyABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (<57.5; 80/66), MD and controls = 0.98 (<50; 100/96), MCI and MD = 0.86 (<49.5; 100/74). Conclusions: ACE-R and Mini-Mental State Examination (MMSE) scores for older adults with MCI and controls were significantly lower than those reported in similar studies. These preliminary findings support the need for establishing reliable cut-off scores for cognitive assessment of older Brazilian adults with low schooling at risk for dementia taking into consideration ecological and local variables.Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro2021-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045Jornal Brasileiro de Psiquiatria v.70 n.1 2021reponame:Jornal Brasileiro de Psiquiatria (Online)instname:Universidade Federal do Rio de Janeiro (UFRJ)instacron:UFRJ10.1590/0047-2085000000310info:eu-repo/semantics/openAccessTavares Júnior,José Wagner LeonelBraga Neto,PedroBonfadini,Janine de CarvalhoBittencourt,LaysLopes,Candida HelenaMendes,LarissaSiqueira Neto,José IbiapinaSousa,ValériaAmaral,AninaCarrilho,Carolina GomesEspindola,Jonatan OliveiraCasali,Maria Eduarda AvanciniVeras,André BarcielaAlves,Gilberto Sousaeng2021-03-29T00:00:00Zoai:scielo:S0047-20852021000100045Revistahttp://portalrev.enfermagem.bvs.br/index.php?issn=0047-2085&lang=ptONGhttps://old.scielo.br/oai/scielo-oai.php||editora@ipub.ufrj.br1982-02080047-2085opendoar:2021-03-29T00:00Jornal Brasileiro de Psiquiatria (Online) - Universidade Federal do Rio de Janeiro (UFRJ)false |
dc.title.none.fl_str_mv |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
title |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
spellingShingle |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level Tavares Júnior,José Wagner Leonel Dementia cognitive screening illiterate Northeast Addenbrooke accuracy |
title_short |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
title_full |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
title_fullStr |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
title_full_unstemmed |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
title_sort |
Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level |
author |
Tavares Júnior,José Wagner Leonel |
author_facet |
Tavares Júnior,José Wagner Leonel Braga Neto,Pedro Bonfadini,Janine de Carvalho Bittencourt,Lays Lopes,Candida Helena Mendes,Larissa Siqueira Neto,José Ibiapina Sousa,Valéria Amaral,Anina Carrilho,Carolina Gomes Espindola,Jonatan Oliveira Casali,Maria Eduarda Avancini Veras,André Barciela Alves,Gilberto Sousa |
author_role |
author |
author2 |
Braga Neto,Pedro Bonfadini,Janine de Carvalho Bittencourt,Lays Lopes,Candida Helena Mendes,Larissa Siqueira Neto,José Ibiapina Sousa,Valéria Amaral,Anina Carrilho,Carolina Gomes Espindola,Jonatan Oliveira Casali,Maria Eduarda Avancini Veras,André Barciela Alves,Gilberto Sousa |
author2_role |
author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Tavares Júnior,José Wagner Leonel Braga Neto,Pedro Bonfadini,Janine de Carvalho Bittencourt,Lays Lopes,Candida Helena Mendes,Larissa Siqueira Neto,José Ibiapina Sousa,Valéria Amaral,Anina Carrilho,Carolina Gomes Espindola,Jonatan Oliveira Casali,Maria Eduarda Avancini Veras,André Barciela Alves,Gilberto Sousa |
dc.subject.por.fl_str_mv |
Dementia cognitive screening illiterate Northeast Addenbrooke accuracy |
topic |
Dementia cognitive screening illiterate Northeast Addenbrooke accuracy |
description |
ABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (<57.5; 80/66), MD and controls = 0.98 (<50; 100/96), MCI and MD = 0.86 (<49.5; 100/74). Conclusions: ACE-R and Mini-Mental State Examination (MMSE) scores for older adults with MCI and controls were significantly lower than those reported in similar studies. These preliminary findings support the need for establishing reliable cut-off scores for cognitive assessment of older Brazilian adults with low schooling at risk for dementia taking into consideration ecological and local variables. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-03-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0047-2085000000310 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro |
publisher.none.fl_str_mv |
Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro |
dc.source.none.fl_str_mv |
Jornal Brasileiro de Psiquiatria v.70 n.1 2021 reponame:Jornal Brasileiro de Psiquiatria (Online) instname:Universidade Federal do Rio de Janeiro (UFRJ) instacron:UFRJ |
instname_str |
Universidade Federal do Rio de Janeiro (UFRJ) |
instacron_str |
UFRJ |
institution |
UFRJ |
reponame_str |
Jornal Brasileiro de Psiquiatria (Online) |
collection |
Jornal Brasileiro de Psiquiatria (Online) |
repository.name.fl_str_mv |
Jornal Brasileiro de Psiquiatria (Online) - Universidade Federal do Rio de Janeiro (UFRJ) |
repository.mail.fl_str_mv |
||editora@ipub.ufrj.br |
_version_ |
1750128247478157312 |