Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level

Detalhes bibliográficos
Autor(a) principal: Tavares Júnior,José Wagner Leonel
Data de Publicação: 2021
Outros Autores: Braga Neto,Pedro, Bonfadini,Janine de Carvalho, Bittencourt,Lays, Lopes,Candida Helena, Mendes,Larissa, Siqueira Neto,José Ibiapina, Sousa,Valéria, Amaral,Anina, Carrilho,Carolina Gomes, Espindola,Jonatan Oliveira, Casali,Maria Eduarda Avancini, Veras,André Barciela, Alves,Gilberto Sousa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Jornal Brasileiro de Psiquiatria (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045
Resumo: ABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (<57.5; 80/66), MD and controls = 0.98 (<50; 100/96), MCI and MD = 0.86 (<49.5; 100/74). Conclusions: ACE-R and Mini-Mental State Examination (MMSE) scores for older adults with MCI and controls were significantly lower than those reported in similar studies. These preliminary findings support the need for establishing reliable cut-off scores for cognitive assessment of older Brazilian adults with low schooling at risk for dementia taking into consideration ecological and local variables.
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spelling Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational levelDementiacognitive screeningilliterateNortheastAddenbrookeaccuracyABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (<57.5; 80/66), MD and controls = 0.98 (<50; 100/96), MCI and MD = 0.86 (<49.5; 100/74). Conclusions: ACE-R and Mini-Mental State Examination (MMSE) scores for older adults with MCI and controls were significantly lower than those reported in similar studies. These preliminary findings support the need for establishing reliable cut-off scores for cognitive assessment of older Brazilian adults with low schooling at risk for dementia taking into consideration ecological and local variables.Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro2021-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045Jornal Brasileiro de Psiquiatria v.70 n.1 2021reponame:Jornal Brasileiro de Psiquiatria (Online)instname:Universidade Federal do Rio de Janeiro (UFRJ)instacron:UFRJ10.1590/0047-2085000000310info:eu-repo/semantics/openAccessTavares Júnior,José Wagner LeonelBraga Neto,PedroBonfadini,Janine de CarvalhoBittencourt,LaysLopes,Candida HelenaMendes,LarissaSiqueira Neto,José IbiapinaSousa,ValériaAmaral,AninaCarrilho,Carolina GomesEspindola,Jonatan OliveiraCasali,Maria Eduarda AvanciniVeras,André BarcielaAlves,Gilberto Sousaeng2021-03-29T00:00:00Zoai:scielo:S0047-20852021000100045Revistahttp://portalrev.enfermagem.bvs.br/index.php?issn=0047-2085&lang=ptONGhttps://old.scielo.br/oai/scielo-oai.php||editora@ipub.ufrj.br1982-02080047-2085opendoar:2021-03-29T00:00Jornal Brasileiro de Psiquiatria (Online) - Universidade Federal do Rio de Janeiro (UFRJ)false
dc.title.none.fl_str_mv Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
title Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
spellingShingle Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
Tavares Júnior,José Wagner Leonel
Dementia
cognitive screening
illiterate
Northeast
Addenbrooke
accuracy
title_short Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
title_full Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
title_fullStr Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
title_full_unstemmed Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
title_sort Clinical characteristics and diagnostic accuracy of the revised Addenbrooke Cognitive Examination (ACE-R) in older adults with a low educational level
author Tavares Júnior,José Wagner Leonel
author_facet Tavares Júnior,José Wagner Leonel
Braga Neto,Pedro
Bonfadini,Janine de Carvalho
Bittencourt,Lays
Lopes,Candida Helena
Mendes,Larissa
Siqueira Neto,José Ibiapina
Sousa,Valéria
Amaral,Anina
Carrilho,Carolina Gomes
Espindola,Jonatan Oliveira
Casali,Maria Eduarda Avancini
Veras,André Barciela
Alves,Gilberto Sousa
author_role author
author2 Braga Neto,Pedro
Bonfadini,Janine de Carvalho
Bittencourt,Lays
Lopes,Candida Helena
Mendes,Larissa
Siqueira Neto,José Ibiapina
Sousa,Valéria
Amaral,Anina
Carrilho,Carolina Gomes
Espindola,Jonatan Oliveira
Casali,Maria Eduarda Avancini
Veras,André Barciela
Alves,Gilberto Sousa
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Tavares Júnior,José Wagner Leonel
Braga Neto,Pedro
Bonfadini,Janine de Carvalho
Bittencourt,Lays
Lopes,Candida Helena
Mendes,Larissa
Siqueira Neto,José Ibiapina
Sousa,Valéria
Amaral,Anina
Carrilho,Carolina Gomes
Espindola,Jonatan Oliveira
Casali,Maria Eduarda Avancini
Veras,André Barciela
Alves,Gilberto Sousa
dc.subject.por.fl_str_mv Dementia
cognitive screening
illiterate
Northeast
Addenbrooke
accuracy
topic Dementia
cognitive screening
illiterate
Northeast
Addenbrooke
accuracy
description ABSTRACT Objective: To determine the diagnostic accuracy of the Addenbrooke’s Cognitive Examination Revised (ACE-R) as a cognitive screening tool for older adults with low levels of schooling and healthy aging, MCI and dementia in Brazil. Methods: All participants underwent neurological and psychiatric examinations and were administered a validated version of ACE-R. Results: A total of 85 participants were evaluated; most were females (84.7%, n = 72). The post hoc analysis showed statistical differences in ACE-R total scores between older adults with mild cognitive impairment (MCI) and controls (p < 0.001) and in subitem scores including verbal fluency, language, visuospatial skills and attention (p < 0.001). The visual-spatial skills subitem was the most strongly correlated with schooling level (r = 0.509, p < 0.001), whereas late, immediate recall and recognition memory were not influenced by schooling. The ACE-R had the best diagnostic accuracy in discriminating between MCI and controls = 0.69 (<57.5; 80/66), MD and controls = 0.98 (<50; 100/96), MCI and MD = 0.86 (<49.5; 100/74). Conclusions: ACE-R and Mini-Mental State Examination (MMSE) scores for older adults with MCI and controls were significantly lower than those reported in similar studies. These preliminary findings support the need for establishing reliable cut-off scores for cognitive assessment of older Brazilian adults with low schooling at risk for dementia taking into consideration ecological and local variables.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0047-20852021000100045
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0047-2085000000310
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.publisher.none.fl_str_mv Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro
publisher.none.fl_str_mv Instituto de Psiquiatria da Universidade Federal do Rio de Janeiro
dc.source.none.fl_str_mv Jornal Brasileiro de Psiquiatria v.70 n.1 2021
reponame:Jornal Brasileiro de Psiquiatria (Online)
instname:Universidade Federal do Rio de Janeiro (UFRJ)
instacron:UFRJ
instname_str Universidade Federal do Rio de Janeiro (UFRJ)
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institution UFRJ
reponame_str Jornal Brasileiro de Psiquiatria (Online)
collection Jornal Brasileiro de Psiquiatria (Online)
repository.name.fl_str_mv Jornal Brasileiro de Psiquiatria (Online) - Universidade Federal do Rio de Janeiro (UFRJ)
repository.mail.fl_str_mv ||editora@ipub.ufrj.br
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