Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UFRN |
| Texto Completo: | https://repositorio.ufrn.br/handle/123456789/31348 |
Resumo: | Visceral leishmaniasis (VL) in pregnant is considered rare. We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the motherfetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in pregnancy |
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Cunha, Francielly TertulinoLopes, Isadora CorreiaOliveira, Francisco Clitson SousaSilva, Igor Thiago Borges de Queiroz e2021-02-02T17:50:32Z2021-02-02T17:50:32Z2019CUNHA, Francielly Tertulino; LOPES, Isadora Correia; OLIVEIRA, Francisco Clitson Sousa; SILVA, Igor Thiago Borges de Queiroz e. Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review. Revista da Sociedade Brasileira de Medicina Tropical, [s. l.], v. 52, p. 1-3, 2019. FapUNIFESP (SciELO). Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100704&tlng=en. Acesso em: 21 jan. 2021. http://dx.doi.org/10.1590/0037-8682-0233-2018.0037-8682 (print)1678-9849 (online)https://repositorio.ufrn.br/handle/123456789/3134810.1590/0037-8682-0233-2018Sociedade Brasileira de Medicina Tropical (SBMT)Attribution-NonCommercial-ShareAlike 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-sa/3.0/br/info:eu-repo/semantics/openAccessVisceral leishmaniasisPregnancyLiposomal amphotericin BVisceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleVisceral leishmaniasis (VL) in pregnant is considered rare. We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the motherfetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in pregnancyengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALVisceralLeishmaniasisPregnant_Silva_2019.pdfVisceralLeishmaniasisPregnant_Silva_2019.pdfapplication/pdf893793https://repositorio.ufrn.br/bitstream/123456789/31348/1/VisceralLeishmaniasisPregnant_Silva_2019.pdf8fc7dd88f32f7cd8a0ddc969846d3d25MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-81037https://repositorio.ufrn.br/bitstream/123456789/31348/2/license_rdf996f8b5afe3136b76594f43bfda24c5eMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/31348/3/license.txte9597aa2854d128fd968be5edc8a28d9MD53TEXTVisceralLeishmaniasisPregnant_Silva_2019.pdf.txtVisceralLeishmaniasisPregnant_Silva_2019.pdf.txtExtracted texttext/plain14524https://repositorio.ufrn.br/bitstream/123456789/31348/4/VisceralLeishmaniasisPregnant_Silva_2019.pdf.txt5967dd7dd5aae6c2df66db5ca2394feeMD54THUMBNAILVisceralLeishmaniasisPregnant_Silva_2019.pdf.jpgVisceralLeishmaniasisPregnant_Silva_2019.pdf.jpgGenerated Thumbnailimage/jpeg1733https://repositorio.ufrn.br/bitstream/123456789/31348/5/VisceralLeishmaniasisPregnant_Silva_2019.pdf.jpg1007781eeabd0a13b4a230bb1a61f910MD55123456789/313482021-02-07 05:25:44.838oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-02-07T08:25:44Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
| dc.title.pt_BR.fl_str_mv |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| title |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| spellingShingle |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review Cunha, Francielly Tertulino Visceral leishmaniasis Pregnancy Liposomal amphotericin B |
| title_short |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| title_full |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| title_fullStr |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| title_full_unstemmed |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| title_sort |
Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review |
| author |
Cunha, Francielly Tertulino |
| author_facet |
Cunha, Francielly Tertulino Lopes, Isadora Correia Oliveira, Francisco Clitson Sousa Silva, Igor Thiago Borges de Queiroz e |
| author_role |
author |
| author2 |
Lopes, Isadora Correia Oliveira, Francisco Clitson Sousa Silva, Igor Thiago Borges de Queiroz e |
| author2_role |
author author author |
| dc.contributor.author.fl_str_mv |
Cunha, Francielly Tertulino Lopes, Isadora Correia Oliveira, Francisco Clitson Sousa Silva, Igor Thiago Borges de Queiroz e |
| dc.subject.por.fl_str_mv |
Visceral leishmaniasis Pregnancy Liposomal amphotericin B |
| topic |
Visceral leishmaniasis Pregnancy Liposomal amphotericin B |
| description |
Visceral leishmaniasis (VL) in pregnant is considered rare. We present the case of a woman with 24 gestational weeks presenting fever, hepatosplenomegaly, pancytopenia, and inversion of albumin/globulin ratio. Anti-rK39 was positive and amastigotes were visualized on myelogram. Treatment with LAmB showed disease improvement. The newborn was born healthy at term, with delivery performed without complications. As VL in pregnancy can progress to death and complications for the motherfetus binomial, inclusion of VL in the differential diagnosis of patients from endemic areas with compatible clinical picture is mandatory. Treatment with LAmB demonstrates safety and high cure rates in pregnancy |
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2019 |
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2019 |
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2021-02-02T17:50:32Z |
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2021-02-02T17:50:32Z |
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article |
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CUNHA, Francielly Tertulino; LOPES, Isadora Correia; OLIVEIRA, Francisco Clitson Sousa; SILVA, Igor Thiago Borges de Queiroz e. Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review. Revista da Sociedade Brasileira de Medicina Tropical, [s. l.], v. 52, p. 1-3, 2019. FapUNIFESP (SciELO). Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100704&tlng=en. Acesso em: 21 jan. 2021. http://dx.doi.org/10.1590/0037-8682-0233-2018. |
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https://repositorio.ufrn.br/handle/123456789/31348 |
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0037-8682 (print) 1678-9849 (online) |
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10.1590/0037-8682-0233-2018 |
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CUNHA, Francielly Tertulino; LOPES, Isadora Correia; OLIVEIRA, Francisco Clitson Sousa; SILVA, Igor Thiago Borges de Queiroz e. Visceral leishmaniasis in pregnant women from Rio Grande do Norte, Brazil: a case report and literature review. Revista da Sociedade Brasileira de Medicina Tropical, [s. l.], v. 52, p. 1-3, 2019. FapUNIFESP (SciELO). Disponível em: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822019000100704&tlng=en. Acesso em: 21 jan. 2021. http://dx.doi.org/10.1590/0037-8682-0233-2018. 0037-8682 (print) 1678-9849 (online) 10.1590/0037-8682-0233-2018 |
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