Effect of end-stage renal disease and diabetes on zinc and copper status
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/54369 http://dx.doi.org/10.1385/bter:112:1:1 |
Resumo: | The aim of this study was to compare the nutritional status of zinc and copper in patients with and without diabetes submitted to chronic hemodialysis. Thirty-three patients with type 2 diabetes (DM group), 30 nondiabetic patients (NDM group), and 20 healthy individuals (control group) were studied. Plasma, erythrocyte, and urinary zinc and plasma copper were obtained from atomic absorption spectrophotometry and ceruloplasmin by immunonephelometry. The anthropometric parameters were similar among the groups. Plasma zinc was lower and erythrocyte zinc was higher in the DM and NDM groups in relation to the control group. No difference in urinary zinc was observed comparing the groups. Plasma copper was higher in the DM group when compared to the NDM and control groups. Ceruloplasmin was similar in the three groups. Serum urea was a positive independent determinant of plasma zinc concentrations. The determinants of erythrocyte zinc were MAMC midarm nuscle circumference and Kt/V dialysis adequacy. The determinants of plasma copper concentration were serum creatinine and serum glucose. The results of this study demonstrate an alteration in the distribution of zinc of patients with chronic kidney disease (CKD) independently of the presence of DM. Also, the status of copper seems not to be influenced by CKD, but only by the metabolic derangements associated with diabetes. |
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Almeida, José Bruno deBatista, Maria NazaréCuppari, LílianPedrosa, Lucia de Fátima CamposAlmeida, Maria das GraçasMedeiros, Anna Cecília Queiroz deCanziani, Maria Eugiènia F.2023-08-03T18:21:47Z2023-08-03T18:21:47Z2006BATISTA, Maria Nazaré; CUPPARI, Lílian; PEDROSA, Lucia de Fátima Campos; ALMEIDA, Maria das Graças; ALMEIDA, José Bruno de; MEDEIROS, Anna Cecília Queiroz de; CANZIANI, Maria Eugiènia F.. Effect of End-Stage Renal Disease and Diabetes on Zinc and Copper Status. Biological Trace Element Research, [S.L.], v. 112, n. 1, p. 1-12, 2006. Springer Science and Business Media LLC. http://dx.doi.org/10.1385/bter:112:1:1. Disponível em: https://link.springer.com/article/10.1385/BTER:112:1:1. Acesso em: 28 jul. 2023.https://repositorio.ufrn.br/handle/123456789/54369http://dx.doi.org/10.1385/bter:112:1:1Springerzinccopperchronic kidney diseasehemodialysisdiabetesEffect of end-stage renal disease and diabetes on zinc and copper statusinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThe aim of this study was to compare the nutritional status of zinc and copper in patients with and without diabetes submitted to chronic hemodialysis. Thirty-three patients with type 2 diabetes (DM group), 30 nondiabetic patients (NDM group), and 20 healthy individuals (control group) were studied. Plasma, erythrocyte, and urinary zinc and plasma copper were obtained from atomic absorption spectrophotometry and ceruloplasmin by immunonephelometry. The anthropometric parameters were similar among the groups. Plasma zinc was lower and erythrocyte zinc was higher in the DM and NDM groups in relation to the control group. No difference in urinary zinc was observed comparing the groups. Plasma copper was higher in the DM group when compared to the NDM and control groups. Ceruloplasmin was similar in the three groups. Serum urea was a positive independent determinant of plasma zinc concentrations. The determinants of erythrocyte zinc were MAMC midarm nuscle circumference and Kt/V dialysis adequacy. The determinants of plasma copper concentration were serum creatinine and serum glucose. The results of this study demonstrate an alteration in the distribution of zinc of patients with chronic kidney disease (CKD) independently of the presence of DM. Also, the status of copper seems not to be influenced by CKD, but only by the metabolic derangements associated with diabetes.engreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessORIGINALEffectEndStageRenal_Almeida_2006.pdfEffectEndStageRenal_Almeida_2006.pdfapplication/pdf163545https://repositorio.ufrn.br/bitstream/123456789/54369/1/EffectEndStageRenal_Almeida_2006.pdf6271481d721b4b4396d553609196e496MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/54369/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52123456789/543692023-08-03 15:22:15.62oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-08-03T18:22:15Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Effect of end-stage renal disease and diabetes on zinc and copper status |
title |
Effect of end-stage renal disease and diabetes on zinc and copper status |
spellingShingle |
Effect of end-stage renal disease and diabetes on zinc and copper status Almeida, José Bruno de zinc copper chronic kidney disease hemodialysis diabetes |
title_short |
Effect of end-stage renal disease and diabetes on zinc and copper status |
title_full |
Effect of end-stage renal disease and diabetes on zinc and copper status |
title_fullStr |
Effect of end-stage renal disease and diabetes on zinc and copper status |
title_full_unstemmed |
Effect of end-stage renal disease and diabetes on zinc and copper status |
title_sort |
Effect of end-stage renal disease and diabetes on zinc and copper status |
author |
Almeida, José Bruno de |
author_facet |
Almeida, José Bruno de Batista, Maria Nazaré Cuppari, Lílian Pedrosa, Lucia de Fátima Campos Almeida, Maria das Graças Medeiros, Anna Cecília Queiroz de Canziani, Maria Eugiènia F. |
author_role |
author |
author2 |
Batista, Maria Nazaré Cuppari, Lílian Pedrosa, Lucia de Fátima Campos Almeida, Maria das Graças Medeiros, Anna Cecília Queiroz de Canziani, Maria Eugiènia F. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Almeida, José Bruno de Batista, Maria Nazaré Cuppari, Lílian Pedrosa, Lucia de Fátima Campos Almeida, Maria das Graças Medeiros, Anna Cecília Queiroz de Canziani, Maria Eugiènia F. |
dc.subject.por.fl_str_mv |
zinc copper chronic kidney disease hemodialysis diabetes |
topic |
zinc copper chronic kidney disease hemodialysis diabetes |
description |
The aim of this study was to compare the nutritional status of zinc and copper in patients with and without diabetes submitted to chronic hemodialysis. Thirty-three patients with type 2 diabetes (DM group), 30 nondiabetic patients (NDM group), and 20 healthy individuals (control group) were studied. Plasma, erythrocyte, and urinary zinc and plasma copper were obtained from atomic absorption spectrophotometry and ceruloplasmin by immunonephelometry. The anthropometric parameters were similar among the groups. Plasma zinc was lower and erythrocyte zinc was higher in the DM and NDM groups in relation to the control group. No difference in urinary zinc was observed comparing the groups. Plasma copper was higher in the DM group when compared to the NDM and control groups. Ceruloplasmin was similar in the three groups. Serum urea was a positive independent determinant of plasma zinc concentrations. The determinants of erythrocyte zinc were MAMC midarm nuscle circumference and Kt/V dialysis adequacy. The determinants of plasma copper concentration were serum creatinine and serum glucose. The results of this study demonstrate an alteration in the distribution of zinc of patients with chronic kidney disease (CKD) independently of the presence of DM. Also, the status of copper seems not to be influenced by CKD, but only by the metabolic derangements associated with diabetes. |
publishDate |
2006 |
dc.date.issued.fl_str_mv |
2006 |
dc.date.accessioned.fl_str_mv |
2023-08-03T18:21:47Z |
dc.date.available.fl_str_mv |
2023-08-03T18:21:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BATISTA, Maria Nazaré; CUPPARI, Lílian; PEDROSA, Lucia de Fátima Campos; ALMEIDA, Maria das Graças; ALMEIDA, José Bruno de; MEDEIROS, Anna Cecília Queiroz de; CANZIANI, Maria Eugiènia F.. Effect of End-Stage Renal Disease and Diabetes on Zinc and Copper Status. Biological Trace Element Research, [S.L.], v. 112, n. 1, p. 1-12, 2006. Springer Science and Business Media LLC. http://dx.doi.org/10.1385/bter:112:1:1. Disponível em: https://link.springer.com/article/10.1385/BTER:112:1:1. Acesso em: 28 jul. 2023. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/54369 |
dc.identifier.doi.none.fl_str_mv |
http://dx.doi.org/10.1385/bter:112:1:1 |
identifier_str_mv |
BATISTA, Maria Nazaré; CUPPARI, Lílian; PEDROSA, Lucia de Fátima Campos; ALMEIDA, Maria das Graças; ALMEIDA, José Bruno de; MEDEIROS, Anna Cecília Queiroz de; CANZIANI, Maria Eugiènia F.. Effect of End-Stage Renal Disease and Diabetes on Zinc and Copper Status. Biological Trace Element Research, [S.L.], v. 112, n. 1, p. 1-12, 2006. Springer Science and Business Media LLC. http://dx.doi.org/10.1385/bter:112:1:1. Disponível em: https://link.springer.com/article/10.1385/BTER:112:1:1. Acesso em: 28 jul. 2023. |
url |
https://repositorio.ufrn.br/handle/123456789/54369 http://dx.doi.org/10.1385/bter:112:1:1 |
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eng |
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Springer |
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Springer |
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