Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/jspui/handle/123456789/29644 |
Resumo: | Objective: To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects with Myotonic dystrophy type 1 (DM1) compared with healthy subjects. Design and methods: Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy. Results: MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test. Conclusions: MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory muscles |
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Evangelista, Morgana de AraújoDias, Fernando Augusto LavezzoDourado Júnior, Mário Emílio TeixeiraNascimento, George CarlosSarmento, AntonioGualdi, Lucien PeroniAliverti, AndreaResquetti, VanessaFregonezi, Guilherme Augusto de Freitas2020-07-15T13:15:49Z2020-07-15T13:15:49Z2017-06-08EVANGELISTA, M.A.; DIAS, F.A.L.; DOURADO JÚNIOR, M.E.T.; NASCIMENTO, G.C.; SARMENTO, A.; GUALDI, L.P.; ALIVERTI, A.; RESQUETI, V.; FREGONEZI, G.A.F.. Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy. PLoS One, v. 12, p. e0177318, 2017. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177318. Acesso em: 15 jul. 2020. https://doi.org/10.1371/journal.pone.01773181932-6203https://repositorio.ufrn.br/jspui/handle/123456789/2964410.1371/journal.pone.0177318Public Library of ScienceAttribution 3.0 Brazilhttp://creativecommons.org/licenses/by/3.0/br/info:eu-repo/semantics/openAccessElectromyographic activityRespiratory musclesNoninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleObjective: To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects with Myotonic dystrophy type 1 (DM1) compared with healthy subjects. Design and methods: Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy. Results: MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test. Conclusions: MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory musclesengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8914https://repositorio.ufrn.br/bitstream/123456789/29644/2/license_rdf4d2950bda3d176f570a9f8b328dfbbefMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/29644/3/license.txte9597aa2854d128fd968be5edc8a28d9MD53ORIGINALNoninvasiveAssessmentRespiratory_Nascimento_2017.pdfNoninvasiveAssessmentRespiratory_Nascimento_2017.pdfapplication/pdf29327360https://repositorio.ufrn.br/bitstream/123456789/29644/1/NoninvasiveAssessmentRespiratory_Nascimento_2017.pdf6561dfb1738a3c3987689da6afca5456MD51123456789/296442023-07-27 17:40:34.283oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-07-27T20:40:34Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
title |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
spellingShingle |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy Evangelista, Morgana de Araújo Electromyographic activity Respiratory muscles |
title_short |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
title_full |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
title_fullStr |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
title_full_unstemmed |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
title_sort |
Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy |
author |
Evangelista, Morgana de Araújo |
author_facet |
Evangelista, Morgana de Araújo Dias, Fernando Augusto Lavezzo Dourado Júnior, Mário Emílio Teixeira Nascimento, George Carlos Sarmento, Antonio Gualdi, Lucien Peroni Aliverti, Andrea Resquetti, Vanessa Fregonezi, Guilherme Augusto de Freitas |
author_role |
author |
author2 |
Dias, Fernando Augusto Lavezzo Dourado Júnior, Mário Emílio Teixeira Nascimento, George Carlos Sarmento, Antonio Gualdi, Lucien Peroni Aliverti, Andrea Resquetti, Vanessa Fregonezi, Guilherme Augusto de Freitas |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Evangelista, Morgana de Araújo Dias, Fernando Augusto Lavezzo Dourado Júnior, Mário Emílio Teixeira Nascimento, George Carlos Sarmento, Antonio Gualdi, Lucien Peroni Aliverti, Andrea Resquetti, Vanessa Fregonezi, Guilherme Augusto de Freitas |
dc.subject.por.fl_str_mv |
Electromyographic activity Respiratory muscles |
topic |
Electromyographic activity Respiratory muscles |
description |
Objective: To evaluate sensitivity/specificity of the maximum relaxation rate (MRR) of inspiratory muscles, amplitude of electromyographic activity of the sternocleidomastoid (SCM), scalene (SCA), parasternal (2ndIS) and rectus abdominis (RA) muscles; lung function and respiratory muscle strength in subjects with Myotonic dystrophy type 1 (DM1) compared with healthy subjects. Design and methods: Quasi-experimental observational study with control group. MRR of inspiratory muscles, lung function and amplitude of the electromyographic activity of SCM, SCA, 2ndIS and RA muscles during maximum inspiratory pressure (PImax), maximum expiratory pressure (PEmax) and sniff nasal inspiratory pressure (SNIP) tests were assessed in eighteen DM1 subjects and eleven healthy. Results: MRR was lower in DM1 group compared to healthy (P = 0.001) and was considered sensitive and specific to identify disease in DM1 and discard it in controls, as well as SNIP% (P = 0.0026), PImax% (P = 0.0077) and PEmax% (P = 0.0002). Contraction time of SCM and SCA was higher in DM1 compared to controls, respectively, during PImax (P = 0.023 and P = 0.017) and SNIP (P = 0.015 and P = .0004). The DM1 group showed lower PImax (P = .0006), PEmax (P = 0.0002), SNIP (P = 0.0014), and higher electromyographic activity of the SCM (P = 0.002) and SCA (P = 0.004) at rest; of 2ndIS (P = 0.003) during PEmax and of SCM (P = 0.02) and SCA (P = 0.03) during SNIP test. Conclusions: MD1 subjects presented restrictive pattern, reduced respiratory muscle strength, muscular electrical activity and MRR when compared to higher compared to controls. In addition, the lower MRR found in MD1 subjects showed to be reliable to sensitivity and specificity in identifying the delayed relaxation of respiratory muscles |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017-06-08 |
dc.date.accessioned.fl_str_mv |
2020-07-15T13:15:49Z |
dc.date.available.fl_str_mv |
2020-07-15T13:15:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
EVANGELISTA, M.A.; DIAS, F.A.L.; DOURADO JÚNIOR, M.E.T.; NASCIMENTO, G.C.; SARMENTO, A.; GUALDI, L.P.; ALIVERTI, A.; RESQUETI, V.; FREGONEZI, G.A.F.. Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy. PLoS One, v. 12, p. e0177318, 2017. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177318. Acesso em: 15 jul. 2020. https://doi.org/10.1371/journal.pone.0177318 |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/jspui/handle/123456789/29644 |
dc.identifier.issn.none.fl_str_mv |
1932-6203 |
dc.identifier.doi.none.fl_str_mv |
10.1371/journal.pone.0177318 |
identifier_str_mv |
EVANGELISTA, M.A.; DIAS, F.A.L.; DOURADO JÚNIOR, M.E.T.; NASCIMENTO, G.C.; SARMENTO, A.; GUALDI, L.P.; ALIVERTI, A.; RESQUETI, V.; FREGONEZI, G.A.F.. Noninvasive assessment of respiratory muscle strength and activity in Myotonic dystrophy. PLoS One, v. 12, p. e0177318, 2017. Disponível em: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177318. Acesso em: 15 jul. 2020. https://doi.org/10.1371/journal.pone.0177318 1932-6203 10.1371/journal.pone.0177318 |
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eng |
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eng |
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Attribution 3.0 Brazil http://creativecommons.org/licenses/by/3.0/br/ |
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Public Library of Science |
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Public Library of Science |
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