Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage

Detalhes bibliográficos
Autor(a) principal: Oliveira, Lucidio Clebeson de
Data de Publicação: 2019
Outros Autores: Oliveira, Eligleidson José Vidal de, Lucena, Eudes Euler de Souza, Cavalcanti, José Rodolfo Lopes de Paiva, Fernandes, João Paulo Costa, Souza Júnior, José Edvan de, Cavalcante, Jeferson de Souza, Azevedo, Eduardo Pereira de, Rêgo, Amália Cinthia Meneses do, Araújo Filho, Irami, Castro, Aline Brito Ferreira de, Guzen, Fausto Pierdoná
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/handle/123456789/32127
Resumo: Three new methods for evaluating facial nerve injury were developed: Spontaneous ocular opening, vibrissae reflex and resistance to upper eyelid lifting. Nerve crush injury was performed by pressing the mice’s facial nerve with forceps for 30 seconds. Scores were given based on the comparison between the behavioral assessment of the injured and non-injured sides. Facial nerve injury is currently evaluated by observing the movement of the mice’s vibrissae and the ocular closure. In this study, three additional tests are proposed. Therefore, a wider evaluation can be accomplished where all the aspects of the facial mimicry can be assessed. The use of the 3 new methods described in this study, in addition to the 2 methods currently used, allows a complete behavioral assessment of facial nerve lesions as several behavioral aspects related to these injuries can be evaluated
id UFRN_6763ce541f55320794a8cca10539f863
oai_identifier_str oai:https://repositorio.ufrn.br:123456789/32127
network_acronym_str UFRN
network_name_str Repositório Institucional da UFRN
repository_id_str
spelling Oliveira, Lucidio Clebeson deOliveira, Eligleidson José Vidal deLucena, Eudes Euler de SouzaCavalcanti, José Rodolfo Lopes de PaivaFernandes, João Paulo CostaSouza Júnior, José Edvan deCavalcante, Jeferson de SouzaAzevedo, Eduardo Pereira deRêgo, Amália Cinthia Meneses doAraújo Filho, IramiCastro, Aline Brito Ferreira deGuzen, Fausto Pierdoná2021-04-09T10:31:32Z2021-04-09T10:31:32Z2019OLIVEIRA, Lucidio Clebeson de; OLIVEIRA, Eligleidson José Vidal de; LUCENA, Eudes Euler de Souza; CAVALCANTI, José Rodolfo Lopes de Paiva; FERNANDES, João Paulo Costa; SOUZA JÚNIOR, José Edvan de; CAVALCANTE, Jeferson de Souza; AZEVEDO, Eduardo Pereira de; RÊGO, Amália Cinthia Meneses do; ARAÚJO FILHO, Irami; CASTRO, Aline Brito Ferreira de; GUZEN, Fausto Pierdoná. Development of new techniques for behavioral evaluation in animals submitted to facial nerve damage. Research Journal of Pharmaceutical, Biological and Chemical Sciences, [s. l.], v. 10, p. 821-829, 2019. Disponível em: https://www.rjpbcs.com/2019_10.2.html. Acesso em: 16 jul. 20200975-8585https://repositorio.ufrn.br/handle/123456789/32127Research Journal of Pharmaceutical, Biological and Chemical SciencesBehavioral evaluationFacial nerveNerve injuryDevelopment of new techniques for behavioral evaluation In animals submitted to facial nerve damageinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThree new methods for evaluating facial nerve injury were developed: Spontaneous ocular opening, vibrissae reflex and resistance to upper eyelid lifting. Nerve crush injury was performed by pressing the mice’s facial nerve with forceps for 30 seconds. Scores were given based on the comparison between the behavioral assessment of the injured and non-injured sides. Facial nerve injury is currently evaluated by observing the movement of the mice’s vibrissae and the ocular closure. In this study, three additional tests are proposed. Therefore, a wider evaluation can be accomplished where all the aspects of the facial mimicry can be assessed. The use of the 3 new methods described in this study, in addition to the 2 methods currently used, allows a complete behavioral assessment of facial nerve lesions as several behavioral aspects related to these injuries can be evaluatedengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/32127/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52TEXTAnimalsFacialDamage_Lucena_2019.pdf.txtAnimalsFacialDamage_Lucena_2019.pdf.txtExtracted texttext/plain22023https://repositorio.ufrn.br/bitstream/123456789/32127/3/AnimalsFacialDamage_Lucena_2019.pdf.txt3697d5eabf3f0d13647bcc6d354180eeMD53THUMBNAILAnimalsFacialDamage_Lucena_2019.pdf.jpgAnimalsFacialDamage_Lucena_2019.pdf.jpgGenerated Thumbnailimage/jpeg1501https://repositorio.ufrn.br/bitstream/123456789/32127/4/AnimalsFacialDamage_Lucena_2019.pdf.jpgdceb03c6f6bd66079d64f1be69be48adMD54123456789/321272022-04-25 19:11:46.93oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2022-04-25T22:11:46Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
title Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
spellingShingle Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
Oliveira, Lucidio Clebeson de
Behavioral evaluation
Facial nerve
Nerve injury
title_short Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
title_full Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
title_fullStr Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
title_full_unstemmed Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
title_sort Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
author Oliveira, Lucidio Clebeson de
author_facet Oliveira, Lucidio Clebeson de
Oliveira, Eligleidson José Vidal de
Lucena, Eudes Euler de Souza
Cavalcanti, José Rodolfo Lopes de Paiva
Fernandes, João Paulo Costa
Souza Júnior, José Edvan de
Cavalcante, Jeferson de Souza
Azevedo, Eduardo Pereira de
Rêgo, Amália Cinthia Meneses do
Araújo Filho, Irami
Castro, Aline Brito Ferreira de
Guzen, Fausto Pierdoná
author_role author
author2 Oliveira, Eligleidson José Vidal de
Lucena, Eudes Euler de Souza
Cavalcanti, José Rodolfo Lopes de Paiva
Fernandes, João Paulo Costa
Souza Júnior, José Edvan de
Cavalcante, Jeferson de Souza
Azevedo, Eduardo Pereira de
Rêgo, Amália Cinthia Meneses do
Araújo Filho, Irami
Castro, Aline Brito Ferreira de
Guzen, Fausto Pierdoná
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Lucidio Clebeson de
Oliveira, Eligleidson José Vidal de
Lucena, Eudes Euler de Souza
Cavalcanti, José Rodolfo Lopes de Paiva
Fernandes, João Paulo Costa
Souza Júnior, José Edvan de
Cavalcante, Jeferson de Souza
Azevedo, Eduardo Pereira de
Rêgo, Amália Cinthia Meneses do
Araújo Filho, Irami
Castro, Aline Brito Ferreira de
Guzen, Fausto Pierdoná
dc.subject.por.fl_str_mv Behavioral evaluation
Facial nerve
Nerve injury
topic Behavioral evaluation
Facial nerve
Nerve injury
description Three new methods for evaluating facial nerve injury were developed: Spontaneous ocular opening, vibrissae reflex and resistance to upper eyelid lifting. Nerve crush injury was performed by pressing the mice’s facial nerve with forceps for 30 seconds. Scores were given based on the comparison between the behavioral assessment of the injured and non-injured sides. Facial nerve injury is currently evaluated by observing the movement of the mice’s vibrissae and the ocular closure. In this study, three additional tests are proposed. Therefore, a wider evaluation can be accomplished where all the aspects of the facial mimicry can be assessed. The use of the 3 new methods described in this study, in addition to the 2 methods currently used, allows a complete behavioral assessment of facial nerve lesions as several behavioral aspects related to these injuries can be evaluated
publishDate 2019
dc.date.issued.fl_str_mv 2019
dc.date.accessioned.fl_str_mv 2021-04-09T10:31:32Z
dc.date.available.fl_str_mv 2021-04-09T10:31:32Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv OLIVEIRA, Lucidio Clebeson de; OLIVEIRA, Eligleidson José Vidal de; LUCENA, Eudes Euler de Souza; CAVALCANTI, José Rodolfo Lopes de Paiva; FERNANDES, João Paulo Costa; SOUZA JÚNIOR, José Edvan de; CAVALCANTE, Jeferson de Souza; AZEVEDO, Eduardo Pereira de; RÊGO, Amália Cinthia Meneses do; ARAÚJO FILHO, Irami; CASTRO, Aline Brito Ferreira de; GUZEN, Fausto Pierdoná. Development of new techniques for behavioral evaluation in animals submitted to facial nerve damage. Research Journal of Pharmaceutical, Biological and Chemical Sciences, [s. l.], v. 10, p. 821-829, 2019. Disponível em: https://www.rjpbcs.com/2019_10.2.html. Acesso em: 16 jul. 2020
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/handle/123456789/32127
dc.identifier.issn.none.fl_str_mv 0975-8585
identifier_str_mv OLIVEIRA, Lucidio Clebeson de; OLIVEIRA, Eligleidson José Vidal de; LUCENA, Eudes Euler de Souza; CAVALCANTI, José Rodolfo Lopes de Paiva; FERNANDES, João Paulo Costa; SOUZA JÚNIOR, José Edvan de; CAVALCANTE, Jeferson de Souza; AZEVEDO, Eduardo Pereira de; RÊGO, Amália Cinthia Meneses do; ARAÚJO FILHO, Irami; CASTRO, Aline Brito Ferreira de; GUZEN, Fausto Pierdoná. Development of new techniques for behavioral evaluation in animals submitted to facial nerve damage. Research Journal of Pharmaceutical, Biological and Chemical Sciences, [s. l.], v. 10, p. 821-829, 2019. Disponível em: https://www.rjpbcs.com/2019_10.2.html. Acesso em: 16 jul. 2020
0975-8585
url https://repositorio.ufrn.br/handle/123456789/32127
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Research Journal of Pharmaceutical, Biological and Chemical Sciences
publisher.none.fl_str_mv Research Journal of Pharmaceutical, Biological and Chemical Sciences
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRN
instname:Universidade Federal do Rio Grande do Norte (UFRN)
instacron:UFRN
instname_str Universidade Federal do Rio Grande do Norte (UFRN)
instacron_str UFRN
institution UFRN
reponame_str Repositório Institucional da UFRN
collection Repositório Institucional da UFRN
bitstream.url.fl_str_mv https://repositorio.ufrn.br/bitstream/123456789/32127/2/license.txt
https://repositorio.ufrn.br/bitstream/123456789/32127/3/AnimalsFacialDamage_Lucena_2019.pdf.txt
https://repositorio.ufrn.br/bitstream/123456789/32127/4/AnimalsFacialDamage_Lucena_2019.pdf.jpg
bitstream.checksum.fl_str_mv e9597aa2854d128fd968be5edc8a28d9
3697d5eabf3f0d13647bcc6d354180ee
dceb03c6f6bd66079d64f1be69be48ad
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)
repository.mail.fl_str_mv
_version_ 1797777073629036544