Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/32127 |
Resumo: | Three new methods for evaluating facial nerve injury were developed: Spontaneous ocular opening, vibrissae reflex and resistance to upper eyelid lifting. Nerve crush injury was performed by pressing the mice’s facial nerve with forceps for 30 seconds. Scores were given based on the comparison between the behavioral assessment of the injured and non-injured sides. Facial nerve injury is currently evaluated by observing the movement of the mice’s vibrissae and the ocular closure. In this study, three additional tests are proposed. Therefore, a wider evaluation can be accomplished where all the aspects of the facial mimicry can be assessed. The use of the 3 new methods described in this study, in addition to the 2 methods currently used, allows a complete behavioral assessment of facial nerve lesions as several behavioral aspects related to these injuries can be evaluated |
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Oliveira, Lucidio Clebeson deOliveira, Eligleidson José Vidal deLucena, Eudes Euler de SouzaCavalcanti, José Rodolfo Lopes de PaivaFernandes, João Paulo CostaSouza Júnior, José Edvan deCavalcante, Jeferson de SouzaAzevedo, Eduardo Pereira deRêgo, Amália Cinthia Meneses doAraújo Filho, IramiCastro, Aline Brito Ferreira deGuzen, Fausto Pierdoná2021-04-09T10:31:32Z2021-04-09T10:31:32Z2019OLIVEIRA, Lucidio Clebeson de; OLIVEIRA, Eligleidson José Vidal de; LUCENA, Eudes Euler de Souza; CAVALCANTI, José Rodolfo Lopes de Paiva; FERNANDES, João Paulo Costa; SOUZA JÚNIOR, José Edvan de; CAVALCANTE, Jeferson de Souza; AZEVEDO, Eduardo Pereira de; RÊGO, Amália Cinthia Meneses do; ARAÚJO FILHO, Irami; CASTRO, Aline Brito Ferreira de; GUZEN, Fausto Pierdoná. Development of new techniques for behavioral evaluation in animals submitted to facial nerve damage. Research Journal of Pharmaceutical, Biological and Chemical Sciences, [s. l.], v. 10, p. 821-829, 2019. Disponível em: https://www.rjpbcs.com/2019_10.2.html. Acesso em: 16 jul. 20200975-8585https://repositorio.ufrn.br/handle/123456789/32127Research Journal of Pharmaceutical, Biological and Chemical SciencesBehavioral evaluationFacial nerveNerve injuryDevelopment of new techniques for behavioral evaluation In animals submitted to facial nerve damageinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThree new methods for evaluating facial nerve injury were developed: Spontaneous ocular opening, vibrissae reflex and resistance to upper eyelid lifting. Nerve crush injury was performed by pressing the mice’s facial nerve with forceps for 30 seconds. Scores were given based on the comparison between the behavioral assessment of the injured and non-injured sides. Facial nerve injury is currently evaluated by observing the movement of the mice’s vibrissae and the ocular closure. In this study, three additional tests are proposed. Therefore, a wider evaluation can be accomplished where all the aspects of the facial mimicry can be assessed. The use of the 3 new methods described in this study, in addition to the 2 methods currently used, allows a complete behavioral assessment of facial nerve lesions as several behavioral aspects related to these injuries can be evaluatedengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/32127/2/license.txte9597aa2854d128fd968be5edc8a28d9MD52TEXTAnimalsFacialDamage_Lucena_2019.pdf.txtAnimalsFacialDamage_Lucena_2019.pdf.txtExtracted texttext/plain22023https://repositorio.ufrn.br/bitstream/123456789/32127/3/AnimalsFacialDamage_Lucena_2019.pdf.txt3697d5eabf3f0d13647bcc6d354180eeMD53THUMBNAILAnimalsFacialDamage_Lucena_2019.pdf.jpgAnimalsFacialDamage_Lucena_2019.pdf.jpgGenerated Thumbnailimage/jpeg1501https://repositorio.ufrn.br/bitstream/123456789/32127/4/AnimalsFacialDamage_Lucena_2019.pdf.jpgdceb03c6f6bd66079d64f1be69be48adMD54123456789/321272022-04-25 19:11:46.93oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2022-04-25T22:11:46Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
title |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
spellingShingle |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage Oliveira, Lucidio Clebeson de Behavioral evaluation Facial nerve Nerve injury |
title_short |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
title_full |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
title_fullStr |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
title_full_unstemmed |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
title_sort |
Development of new techniques for behavioral evaluation In animals submitted to facial nerve damage |
author |
Oliveira, Lucidio Clebeson de |
author_facet |
Oliveira, Lucidio Clebeson de Oliveira, Eligleidson José Vidal de Lucena, Eudes Euler de Souza Cavalcanti, José Rodolfo Lopes de Paiva Fernandes, João Paulo Costa Souza Júnior, José Edvan de Cavalcante, Jeferson de Souza Azevedo, Eduardo Pereira de Rêgo, Amália Cinthia Meneses do Araújo Filho, Irami Castro, Aline Brito Ferreira de Guzen, Fausto Pierdoná |
author_role |
author |
author2 |
Oliveira, Eligleidson José Vidal de Lucena, Eudes Euler de Souza Cavalcanti, José Rodolfo Lopes de Paiva Fernandes, João Paulo Costa Souza Júnior, José Edvan de Cavalcante, Jeferson de Souza Azevedo, Eduardo Pereira de Rêgo, Amália Cinthia Meneses do Araújo Filho, Irami Castro, Aline Brito Ferreira de Guzen, Fausto Pierdoná |
author2_role |
author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Oliveira, Lucidio Clebeson de Oliveira, Eligleidson José Vidal de Lucena, Eudes Euler de Souza Cavalcanti, José Rodolfo Lopes de Paiva Fernandes, João Paulo Costa Souza Júnior, José Edvan de Cavalcante, Jeferson de Souza Azevedo, Eduardo Pereira de Rêgo, Amália Cinthia Meneses do Araújo Filho, Irami Castro, Aline Brito Ferreira de Guzen, Fausto Pierdoná |
dc.subject.por.fl_str_mv |
Behavioral evaluation Facial nerve Nerve injury |
topic |
Behavioral evaluation Facial nerve Nerve injury |
description |
Three new methods for evaluating facial nerve injury were developed: Spontaneous ocular opening, vibrissae reflex and resistance to upper eyelid lifting. Nerve crush injury was performed by pressing the mice’s facial nerve with forceps for 30 seconds. Scores were given based on the comparison between the behavioral assessment of the injured and non-injured sides. Facial nerve injury is currently evaluated by observing the movement of the mice’s vibrissae and the ocular closure. In this study, three additional tests are proposed. Therefore, a wider evaluation can be accomplished where all the aspects of the facial mimicry can be assessed. The use of the 3 new methods described in this study, in addition to the 2 methods currently used, allows a complete behavioral assessment of facial nerve lesions as several behavioral aspects related to these injuries can be evaluated |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019 |
dc.date.accessioned.fl_str_mv |
2021-04-09T10:31:32Z |
dc.date.available.fl_str_mv |
2021-04-09T10:31:32Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
OLIVEIRA, Lucidio Clebeson de; OLIVEIRA, Eligleidson José Vidal de; LUCENA, Eudes Euler de Souza; CAVALCANTI, José Rodolfo Lopes de Paiva; FERNANDES, João Paulo Costa; SOUZA JÚNIOR, José Edvan de; CAVALCANTE, Jeferson de Souza; AZEVEDO, Eduardo Pereira de; RÊGO, Amália Cinthia Meneses do; ARAÚJO FILHO, Irami; CASTRO, Aline Brito Ferreira de; GUZEN, Fausto Pierdoná. Development of new techniques for behavioral evaluation in animals submitted to facial nerve damage. Research Journal of Pharmaceutical, Biological and Chemical Sciences, [s. l.], v. 10, p. 821-829, 2019. Disponível em: https://www.rjpbcs.com/2019_10.2.html. Acesso em: 16 jul. 2020 |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/32127 |
dc.identifier.issn.none.fl_str_mv |
0975-8585 |
identifier_str_mv |
OLIVEIRA, Lucidio Clebeson de; OLIVEIRA, Eligleidson José Vidal de; LUCENA, Eudes Euler de Souza; CAVALCANTI, José Rodolfo Lopes de Paiva; FERNANDES, João Paulo Costa; SOUZA JÚNIOR, José Edvan de; CAVALCANTE, Jeferson de Souza; AZEVEDO, Eduardo Pereira de; RÊGO, Amália Cinthia Meneses do; ARAÚJO FILHO, Irami; CASTRO, Aline Brito Ferreira de; GUZEN, Fausto Pierdoná. Development of new techniques for behavioral evaluation in animals submitted to facial nerve damage. Research Journal of Pharmaceutical, Biological and Chemical Sciences, [s. l.], v. 10, p. 821-829, 2019. Disponível em: https://www.rjpbcs.com/2019_10.2.html. Acesso em: 16 jul. 2020 0975-8585 |
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https://repositorio.ufrn.br/handle/123456789/32127 |
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eng |
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eng |
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Research Journal of Pharmaceutical, Biological and Chemical Sciences |
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Research Journal of Pharmaceutical, Biological and Chemical Sciences |
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