Vitamina D na Síndrome dos Ovários Policísticos: revisão da literatura

• Autor(a) principal: Sales, Lauriana da Silva
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/handle/123456789/40077
• topic: Síndrome do Ovário Policístico; Vitamina D

Polycystic ovary syndrome (PCOS) is one of the most common endocrinopathies in women of reproductive age, and is often associated with insulin resistance (IR), obesity, and dyslipidemia. It is characterized by hyperandrogenism that can be manifested by hirsutism, acne, seborrhea, alopecia, menstrual irregularity, obesity and ovarian cysts. This syndrome modulates the metabolic and hormonal processes, increases the risk of infertility, where the treatment of PCOS is directed to regularization of menstruation and recovery of fertility, in which vitamin D may play a key role in this treatment. The present review of literature aims to evaluate the role of vitamin D supplementation in PCOS. The review was carried out in the PubMed, Lilacs and Scopus databases, with papers published between 2006 and 2017. Selected studies evaluated the effects of vitamin D on PCOS. Evidence shows the relationship between metabolic changes and vitamin D deficiency, low levels of 25-hydroxyvitamin D (25 (OH) D) associated with IR, ovulatory and menstrual irregularities, decreased gestational success, hyperandrogenism and obesity. In addition, 67 to 85% of women diagnosed with PCOS have serum concentrations of 25 (OH) D <20 ng / ml. Studies have shown beneficial effects of vitamin D supplementation in patients with PCOS, since there is a relationship between vitamin D and reproductive function. However more intervention studies are needed to prove this hypothesis.