Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration

Detalhes bibliográficos
Autor(a) principal: Yanovsky, Yevgenij
Data de Publicação: 2014
Outros Autores: Ciatipis, Mareva, Draguhn, Andreas, Tort, Adriano Bretanha Lopes, Brankacˇk, Jurij
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/jspui/handle/1/11808
Resumo: Different types of network oscillations occur in different behavioral, cognitive, or vigilance states. The rodent hippocampus expresses prominentoscillations atfrequencies between 4 and 12Hz,which are superimposed by phase-coupledoscillations (30 –100Hz).These patterns entrain multineuronal activity over large distances and have been implicated in sensory information processing and memory formation. Here we report a new type of oscillation at near- frequencies (2– 4 Hz) in the hippocampus of urethane-anesthetized mice. The rhythm is highly coherent with nasal respiration and with rhythmic field potentials in the olfactory bulb: hence, we called it hippocampal respiration-induced oscillations. Despite the similarity in frequency range, several features distinguish this pattern from locally generatedoscillations: hippocampal respiration-induced oscillations have a unique laminar amplitude profile, are resistant to atropine, couple differentlytooscillations, and are abolished when nasal airflow is bypassed bytracheotomy. Hippocampal neurons are entrained by both the respiration-induced rhythm and concurrent oscillations, suggesting a direct interaction between endogenous activity in the hippocampus and nasal respiratory inputs. Our results demonstrate that nasal respiration strongly modulates hippocampal network activity in mice, providing a long-range synchronizing signal between olfactory and hippocampal networks.
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spelling Yanovsky, YevgenijCiatipis, MarevaDraguhn, AndreasTort, Adriano Bretanha LopesBrankacˇk, Jurij2014-04-30T12:02:19Z2014-04-30T12:02:19Z2014-04-23Yevgenij, Yanovsky et al. Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration (2014). The Journal of Neuroscience. 34(17), 5949 –5964.5287-13https://repositorio.ufrn.br/jspui/handle/1/11808Different types of network oscillations occur in different behavioral, cognitive, or vigilance states. The rodent hippocampus expresses prominentoscillations atfrequencies between 4 and 12Hz,which are superimposed by phase-coupledoscillations (30 –100Hz).These patterns entrain multineuronal activity over large distances and have been implicated in sensory information processing and memory formation. Here we report a new type of oscillation at near- frequencies (2– 4 Hz) in the hippocampus of urethane-anesthetized mice. The rhythm is highly coherent with nasal respiration and with rhythmic field potentials in the olfactory bulb: hence, we called it hippocampal respiration-induced oscillations. Despite the similarity in frequency range, several features distinguish this pattern from locally generatedoscillations: hippocampal respiration-induced oscillations have a unique laminar amplitude profile, are resistant to atropine, couple differentlytooscillations, and are abolished when nasal airflow is bypassed bytracheotomy. Hippocampal neurons are entrained by both the respiration-induced rhythm and concurrent oscillations, suggesting a direct interaction between endogenous activity in the hippocampus and nasal respiratory inputs. Our results demonstrate that nasal respiration strongly modulates hippocampal network activity in mice, providing a long-range synchronizing signal between olfactory and hippocampal networks.engOscillationsHippocampusNetwork oscillationsRodentRhythmUrethaneSlow Oscillations in the Mouse Hippocampus Entrained by Nasal Respirationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALAdrianoTort_Slow Oscillations.pdfAdrianoTort_Slow Oscillations.pdfapplication/pdf4847487https://repositorio.ufrn.br/bitstream/1/11808/1/AdrianoTort_Slow%20Oscillations.pdfe95010f82f52780a5a85c52ad2695660MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81563https://repositorio.ufrn.br/bitstream/1/11808/2/license.txt0d0d8fbe390275e816b5edb78063b7afMD52TEXTAdrianoTort_Slow Oscillations.pdf.txtAdrianoTort_Slow Oscillations.pdf.txtExtracted texttext/plain76140https://repositorio.ufrn.br/bitstream/1/11808/7/AdrianoTort_Slow%20Oscillations.pdf.txt9790f2c55fc9d16409f923911b450dd8MD57THUMBNAILAdrianoTort_Slow Oscillations.pdf.jpgAdrianoTort_Slow Oscillations.pdf.jpgIM Thumbnailimage/jpeg12237https://repositorio.ufrn.br/bitstream/1/11808/8/AdrianoTort_Slow%20Oscillations.pdf.jpga90b00b8c9e1011d2a65f04e34cdac19MD581/118082021-07-08 11:27:24.657oai:https://repositorio.ufrn.br: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ório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-07-08T14:27:24Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
title Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
spellingShingle Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
Yanovsky, Yevgenij
Oscillations
Hippocampus
Network oscillations
Rodent
Rhythm
Urethane
title_short Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
title_full Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
title_fullStr Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
title_full_unstemmed Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
title_sort Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration
author Yanovsky, Yevgenij
author_facet Yanovsky, Yevgenij
Ciatipis, Mareva
Draguhn, Andreas
Tort, Adriano Bretanha Lopes
Brankacˇk, Jurij
author_role author
author2 Ciatipis, Mareva
Draguhn, Andreas
Tort, Adriano Bretanha Lopes
Brankacˇk, Jurij
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Yanovsky, Yevgenij
Ciatipis, Mareva
Draguhn, Andreas
Tort, Adriano Bretanha Lopes
Brankacˇk, Jurij
dc.subject.por.fl_str_mv Oscillations
Hippocampus
Network oscillations
Rodent
Rhythm
Urethane
topic Oscillations
Hippocampus
Network oscillations
Rodent
Rhythm
Urethane
description Different types of network oscillations occur in different behavioral, cognitive, or vigilance states. The rodent hippocampus expresses prominentoscillations atfrequencies between 4 and 12Hz,which are superimposed by phase-coupledoscillations (30 –100Hz).These patterns entrain multineuronal activity over large distances and have been implicated in sensory information processing and memory formation. Here we report a new type of oscillation at near- frequencies (2– 4 Hz) in the hippocampus of urethane-anesthetized mice. The rhythm is highly coherent with nasal respiration and with rhythmic field potentials in the olfactory bulb: hence, we called it hippocampal respiration-induced oscillations. Despite the similarity in frequency range, several features distinguish this pattern from locally generatedoscillations: hippocampal respiration-induced oscillations have a unique laminar amplitude profile, are resistant to atropine, couple differentlytooscillations, and are abolished when nasal airflow is bypassed bytracheotomy. Hippocampal neurons are entrained by both the respiration-induced rhythm and concurrent oscillations, suggesting a direct interaction between endogenous activity in the hippocampus and nasal respiratory inputs. Our results demonstrate that nasal respiration strongly modulates hippocampal network activity in mice, providing a long-range synchronizing signal between olfactory and hippocampal networks.
publishDate 2014
dc.date.accessioned.fl_str_mv 2014-04-30T12:02:19Z
dc.date.available.fl_str_mv 2014-04-30T12:02:19Z
dc.date.issued.fl_str_mv 2014-04-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Yevgenij, Yanovsky et al. Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration (2014). The Journal of Neuroscience. 34(17), 5949 –5964.
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/jspui/handle/1/11808
dc.identifier.issn.none.fl_str_mv 5287-13
identifier_str_mv Yevgenij, Yanovsky et al. Slow Oscillations in the Mouse Hippocampus Entrained by Nasal Respiration (2014). The Journal of Neuroscience. 34(17), 5949 –5964.
5287-13
url https://repositorio.ufrn.br/jspui/handle/1/11808
dc.language.iso.fl_str_mv eng
language eng
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