ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome

Detalhes bibliográficos
Autor(a) principal: Godeiro Junior, Clécio de Oliveira
Data de Publicação: 2020
Outros Autores: Pessoa Neto, Agábio Diógenes, Aquino, Bárbara Cristina Vieira de, Brito, Paulo Santiago de Morais, Silva, Rodrigo de Alencar e, Moreira Neto, Manuel, Barsottini, Orlando Graziani Povoas, Dutra, Lívia Almeida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/handle/123456789/52793
Resumo: Anti Ma 2 encephalitis is an autoimmune encephalitis, usually paraneoplastic, characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. Limbic encephalitis (LE) is the most common manifestation. Anti-Ma2 LE can also be manifested as a pure psychiatric disturbance associated or not with hypokinesia. Other patients exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, due to diencephalic and/or upper brainstem involvement. These cases are challenging and demand extensive work-up for differential diagnosis.
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spelling Godeiro Junior, Clécio de OliveiraPessoa Neto, Agábio DiógenesAquino, Bárbara Cristina Vieira deBrito, Paulo Santiago de MoraisSilva, Rodrigo de Alencar eMoreira Neto, ManuelBarsottini, Orlando Graziani PovoasDutra, Lívia Almeida0000-0002-4312-16332023-06-20T20:13:23Z2023-06-20T20:13:23Z2020-11-03GODEIRO JUNIOR, Clécio de Oliveira; PESSOA NETO, Agábio Diógenes; AQUINO, Bárbara Cristina Vieira de; BRITO, Paulo Santiago de Morais; SILVA, Rodrigo de Alencar e; MOREIRA NETO, Manuel; BARSOTTINI, Orlando Graziani Povoas; DUTRA, Lívia Almeida. ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome. Interdisciplinary Neurosurgery, [S.L.], v. 23, p. 100980, mar. 2021. Elsevier BV. http://dx.doi.org/10.1016/j.inat.2020.100980. Disponível em: https://www.sciencedirect.com/science/article/pii/S2214751920305417?via%3Dihub. Acesso em: 20 jun. 2023.https://repositorio.ufrn.br/handle/123456789/5279310.1016/j.inat.2020.100980ElsevierAttribution-NonCommercial-NoDerivs 3.0 Brazilhttp://creativecommons.org/licenses/by-nc-nd/3.0/br/info:eu-repo/semantics/openAccessparaneoplastic encephalitisdiencephalic lesionautoimmunityANTI-MA2 encephalitis mimicking diencephalic demyelinating syndromeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAnti Ma 2 encephalitis is an autoimmune encephalitis, usually paraneoplastic, characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. Limbic encephalitis (LE) is the most common manifestation. Anti-Ma2 LE can also be manifested as a pure psychiatric disturbance associated or not with hypokinesia. Other patients exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, due to diencephalic and/or upper brainstem involvement. These cases are challenging and demand extensive work-up for differential diagnosis.engreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALANTI-MA2EncephalitisMimicking_GodeiroJunior_Etal_2022.pdfANTI-MA2EncephalitisMimicking_GodeiroJunior_Etal_2022.pdfapplication/pdf939635https://repositorio.ufrn.br/bitstream/123456789/52793/1/ANTI-MA2EncephalitisMimicking_GodeiroJunior_Etal_2022.pdf57e23651fca50339db1a16bb45ad9182MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8811https://repositorio.ufrn.br/bitstream/123456789/52793/2/license_rdfe39d27027a6cc9cb039ad269a5db8e34MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/52793/3/license.txte9597aa2854d128fd968be5edc8a28d9MD53123456789/527932023-06-20 17:13:52.627oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2023-06-20T20:13:52Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
title ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
spellingShingle ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
Godeiro Junior, Clécio de Oliveira
paraneoplastic encephalitis
diencephalic lesion
autoimmunity
title_short ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
title_full ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
title_fullStr ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
title_full_unstemmed ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
title_sort ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome
author Godeiro Junior, Clécio de Oliveira
author_facet Godeiro Junior, Clécio de Oliveira
Pessoa Neto, Agábio Diógenes
Aquino, Bárbara Cristina Vieira de
Brito, Paulo Santiago de Morais
Silva, Rodrigo de Alencar e
Moreira Neto, Manuel
Barsottini, Orlando Graziani Povoas
Dutra, Lívia Almeida
author_role author
author2 Pessoa Neto, Agábio Diógenes
Aquino, Bárbara Cristina Vieira de
Brito, Paulo Santiago de Morais
Silva, Rodrigo de Alencar e
Moreira Neto, Manuel
Barsottini, Orlando Graziani Povoas
Dutra, Lívia Almeida
author2_role author
author
author
author
author
author
author
dc.contributor.authorID.pt_BR.fl_str_mv 0000-0002-4312-1633
dc.contributor.author.fl_str_mv Godeiro Junior, Clécio de Oliveira
Pessoa Neto, Agábio Diógenes
Aquino, Bárbara Cristina Vieira de
Brito, Paulo Santiago de Morais
Silva, Rodrigo de Alencar e
Moreira Neto, Manuel
Barsottini, Orlando Graziani Povoas
Dutra, Lívia Almeida
dc.subject.por.fl_str_mv paraneoplastic encephalitis
diencephalic lesion
autoimmunity
topic paraneoplastic encephalitis
diencephalic lesion
autoimmunity
description Anti Ma 2 encephalitis is an autoimmune encephalitis, usually paraneoplastic, characterized by isolated or combined limbic, diencephalic, or brainstem dysfunction. Limbic encephalitis (LE) is the most common manifestation. Anti-Ma2 LE can also be manifested as a pure psychiatric disturbance associated or not with hypokinesia. Other patients exhibit excessive daytime sleepiness, vertical ophthalmoparesis, or both associated with LE, due to diencephalic and/or upper brainstem involvement. These cases are challenging and demand extensive work-up for differential diagnosis.
publishDate 2020
dc.date.issued.fl_str_mv 2020-11-03
dc.date.accessioned.fl_str_mv 2023-06-20T20:13:23Z
dc.date.available.fl_str_mv 2023-06-20T20:13:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv GODEIRO JUNIOR, Clécio de Oliveira; PESSOA NETO, Agábio Diógenes; AQUINO, Bárbara Cristina Vieira de; BRITO, Paulo Santiago de Morais; SILVA, Rodrigo de Alencar e; MOREIRA NETO, Manuel; BARSOTTINI, Orlando Graziani Povoas; DUTRA, Lívia Almeida. ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome. Interdisciplinary Neurosurgery, [S.L.], v. 23, p. 100980, mar. 2021. Elsevier BV. http://dx.doi.org/10.1016/j.inat.2020.100980. Disponível em: https://www.sciencedirect.com/science/article/pii/S2214751920305417?via%3Dihub. Acesso em: 20 jun. 2023.
dc.identifier.uri.fl_str_mv https://repositorio.ufrn.br/handle/123456789/52793
dc.identifier.doi.none.fl_str_mv 10.1016/j.inat.2020.100980
identifier_str_mv GODEIRO JUNIOR, Clécio de Oliveira; PESSOA NETO, Agábio Diógenes; AQUINO, Bárbara Cristina Vieira de; BRITO, Paulo Santiago de Morais; SILVA, Rodrigo de Alencar e; MOREIRA NETO, Manuel; BARSOTTINI, Orlando Graziani Povoas; DUTRA, Lívia Almeida. ANTI-MA2 encephalitis mimicking diencephalic demyelinating syndrome. Interdisciplinary Neurosurgery, [S.L.], v. 23, p. 100980, mar. 2021. Elsevier BV. http://dx.doi.org/10.1016/j.inat.2020.100980. Disponível em: https://www.sciencedirect.com/science/article/pii/S2214751920305417?via%3Dihub. Acesso em: 20 jun. 2023.
10.1016/j.inat.2020.100980
url https://repositorio.ufrn.br/handle/123456789/52793
dc.language.iso.fl_str_mv eng
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