Coupled variability in primary sensory areas and the hippocampus during spontaneous activity
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/jspui/handle/123456789/22590 |
Resumo: | The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity. |
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Vasconcelos, NivaldoA. P. deSoares-Cunha, CarinaRodrigues, Ana JoãoRibeiro, Sidarta Tollendal GomesSousa, Nuno2017-04-10T12:33:52Z2017-04-10T12:33:52Z2017-04-10https://repositorio.ufrn.br/jspui/handle/123456789/22590engScientific ReportNeural encodingSensory processingCoupled variability in primary sensory areas and the hippocampus during spontaneous activityinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThe cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNLICENSElicense.txtlicense.txttext/plain; charset=utf-81569https://repositorio.ufrn.br/bitstream/123456789/22590/2/license.txt6e6f57145bc87daf99079f06b081ff9fMD52ORIGINALSidartaRibeiro_ICe_2017_Coupled variability.pdfSidartaRibeiro_ICe_2017_Coupled variability.pdfapplication/pdf1323316https://repositorio.ufrn.br/bitstream/123456789/22590/1/SidartaRibeiro_ICe_2017_Coupled%20variability.pdf08c2f437589feac4d402c9dadc0f7fdaMD51TEXTSidartaRibeiro_ICe_2017_Coupled variability.pdf.txtSidartaRibeiro_ICe_2017_Coupled variability.pdf.txtExtracted texttext/plain37191https://repositorio.ufrn.br/bitstream/123456789/22590/5/SidartaRibeiro_ICe_2017_Coupled%20variability.pdf.txt7ee57a145b4b2ec5debd4a3b94bb85edMD55THUMBNAILSidartaRibeiro_ICe_2017_Coupled variability.pdf.jpgSidartaRibeiro_ICe_2017_Coupled variability.pdf.jpgIM Thumbnailimage/jpeg9517https://repositorio.ufrn.br/bitstream/123456789/22590/6/SidartaRibeiro_ICe_2017_Coupled%20variability.pdf.jpg818f9aba03cecab87140ccd4bb55dfc7MD56123456789/225902021-07-10 19:20:03.886oai:https://repositorio.ufrn.br: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ório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-07-10T22:20:03Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
title |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
spellingShingle |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity Vasconcelos, NivaldoA. P. de Neural encoding Sensory processing |
title_short |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
title_full |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
title_fullStr |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
title_full_unstemmed |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
title_sort |
Coupled variability in primary sensory areas and the hippocampus during spontaneous activity |
author |
Vasconcelos, NivaldoA. P. de |
author_facet |
Vasconcelos, NivaldoA. P. de Soares-Cunha, Carina Rodrigues, Ana João Ribeiro, Sidarta Tollendal Gomes Sousa, Nuno |
author_role |
author |
author2 |
Soares-Cunha, Carina Rodrigues, Ana João Ribeiro, Sidarta Tollendal Gomes Sousa, Nuno |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Vasconcelos, NivaldoA. P. de Soares-Cunha, Carina Rodrigues, Ana João Ribeiro, Sidarta Tollendal Gomes Sousa, Nuno |
dc.subject.por.fl_str_mv |
Neural encoding Sensory processing |
topic |
Neural encoding Sensory processing |
description |
The cerebral cortex is an anatomically divided and functionally specialized structure. It includes distinct areas, which work on different states over time. The structural features of spiking activity in sensory cortices have been characterized during spontaneous and evoked activity. However, the coordination among cortical and sub-cortical neurons during spontaneous activity across different states remains poorly characterized. We addressed this issue by studying the temporal coupling of spiking variability recorded from primary sensory cortices and hippocampus of anesthetized or freely behaving rats. During spontaneous activity, spiking variability was highly correlated across primary cortical sensory areas at both small and large spatial scales, whereas the cortico-hippocampal correlation was modest. This general pattern of spiking variability was observed under urethane anesthesia, as well as during waking, slow-wave sleep and rapid-eye-movement sleep, and was unchanged by novel stimulation. These results support the notion that primary sensory areas are strongly coupled during spontaneous activity. |
publishDate |
2017 |
dc.date.accessioned.fl_str_mv |
2017-04-10T12:33:52Z |
dc.date.available.fl_str_mv |
2017-04-10T12:33:52Z |
dc.date.issued.fl_str_mv |
2017-04-10 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/jspui/handle/123456789/22590 |
url |
https://repositorio.ufrn.br/jspui/handle/123456789/22590 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Scientific Report |
publisher.none.fl_str_mv |
Scientific Report |
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UFRN |
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UFRN |
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