Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRN |
Texto Completo: | https://repositorio.ufrn.br/handle/123456789/31181 |
Resumo: | Backoground: Evidence available in the literature suggests that physical exercise increases the release of brain-derived neurotrophic factor (BDNF) in humans and may possibly be related to improvements in executive function. However, studies of this phenomenon in adolescents are still scarce. The objective of this work is to describe the protocol for a systematic review (SR) and meta-analysis of interventional studies aiming to determine the effect of physical exercise on BDNF levels and executive function in adolescents. Methods: This protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and by the Cochrane Handbook of Systematic Reviews of Interventions. The databases to be searched are PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, SPORTDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. Interventional studies conducted on adolescents with different exercise protocols and evaluations of BDNF levels and executive function in pre- and post-intervention periods will be included in the systematic review. The characteristics of the studies, participants, and main results will be described, then the evaluation of the risk of biases and the level of evidence obtained by the protocol will be assessed. The selection of studies, data extraction, and evaluation of the methodological quality will be performed by 2 experienced reviewers independently. Conclusion: The systematic review will present the effects of the practice of physical exercises on the BDNF and executive function levels. The results will strengthen the interventions with the focus on the brain health of adolescents through general orientations and the evidences described shall direct future research. PROSPERO registration number: CRD42018110683 Abbreviations: BDNF = brain-derived neurotrophic factor, CPF = prefrontal cortex, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, SR = systematic review |
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Azevedo, Kesley Pablo Morais deOliveira Segundo, Victor Hugo deMedeiros, Gidyenne Christine Bandeira Silva deMata, Ádala Nayana de SousaGarcía, Daniel ÁngelLeitão, José Carlos Gomes de CarvalhoKnackfuss, Maria IranyPiuvezam, Grasiela2021-01-05T13:57:46Z2021-01-05T13:57:46Z2019-07AZEVEDO, Kesley Pablo Morais de; OLIVEIRA SEGUNDO, Victor Hugo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; MATA, Ádala Nayana de Sousa; GARCÍA, Daniel Ángel; LEITÃO, José Carlos Gomes de Carvalho; KNACKFUSS, Maria Irany; PIUVEZAM, Grasiela. Effects of exercise on the levels of BDNF and executive function in adolescents. Medicine, [s. l.], v. 98, n. 28, p. 1-5, jul. 2019. Ovid Technologies (Wolters Kluwer Health). Disponível em: https://journals.lww.com/md-journal/FullText/2019/07120/Effects_of_exercise_on_the_levels_of_BDNF_and.87.aspx. Acesso em: 21 ago. 2020. http://dx.doi.org/10.1097/md.0000000000016445.0025-79741536-5964https://repositorio.ufrn.br/handle/123456789/3118110.1097/md.0000000000016445Lippincott, Williams & WilkinsAttribution 3.0 Brazilhttp://creativecommons.org/licenses/by/3.0/br/info:eu-repo/semantics/openAccessAdolescentBDNFExecutive functionExerciseSystematic reviewEffects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBackoground: Evidence available in the literature suggests that physical exercise increases the release of brain-derived neurotrophic factor (BDNF) in humans and may possibly be related to improvements in executive function. However, studies of this phenomenon in adolescents are still scarce. The objective of this work is to describe the protocol for a systematic review (SR) and meta-analysis of interventional studies aiming to determine the effect of physical exercise on BDNF levels and executive function in adolescents. Methods: This protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and by the Cochrane Handbook of Systematic Reviews of Interventions. The databases to be searched are PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, SPORTDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. Interventional studies conducted on adolescents with different exercise protocols and evaluations of BDNF levels and executive function in pre- and post-intervention periods will be included in the systematic review. The characteristics of the studies, participants, and main results will be described, then the evaluation of the risk of biases and the level of evidence obtained by the protocol will be assessed. The selection of studies, data extraction, and evaluation of the methodological quality will be performed by 2 experienced reviewers independently. Conclusion: The systematic review will present the effects of the practice of physical exercises on the BDNF and executive function levels. The results will strengthen the interventions with the focus on the brain health of adolescents through general orientations and the evidences described shall direct future research. PROSPERO registration number: CRD42018110683 Abbreviations: BDNF = brain-derived neurotrophic factor, CPF = prefrontal cortex, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, SR = systematic reviewengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALEffectsExerciseAdolescents_Mata_2019.pdfEffectsExerciseAdolescents_Mata_2019.pdfapplication/pdf266583https://repositorio.ufrn.br/bitstream/123456789/31181/1/EffectsExerciseAdolescents_Mata_2019.pdf1cac44eac5887fab94767f8d61473e62MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8914https://repositorio.ufrn.br/bitstream/123456789/31181/2/license_rdf4d2950bda3d176f570a9f8b328dfbbefMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/31181/3/license.txte9597aa2854d128fd968be5edc8a28d9MD53TEXTEffectsExerciseAdolescents_Mata_2019.pdf.txtEffectsExerciseAdolescents_Mata_2019.pdf.txtExtracted texttext/plain23733https://repositorio.ufrn.br/bitstream/123456789/31181/4/EffectsExerciseAdolescents_Mata_2019.pdf.txt69fbd9c1d72bb071084d135653294eecMD54THUMBNAILEffectsExerciseAdolescents_Mata_2019.pdf.jpgEffectsExerciseAdolescents_Mata_2019.pdf.jpgGenerated Thumbnailimage/jpeg1805https://repositorio.ufrn.br/bitstream/123456789/31181/5/EffectsExerciseAdolescents_Mata_2019.pdf.jpg226db4ae6cb8d35dc21fea59fe6343c3MD55123456789/311812021-01-10 04:54:15.994oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-01-10T07:54:15Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false |
dc.title.pt_BR.fl_str_mv |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
title |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
spellingShingle |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis Azevedo, Kesley Pablo Morais de Adolescent BDNF Executive function Exercise Systematic review |
title_short |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
title_full |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
title_fullStr |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
title_full_unstemmed |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
title_sort |
Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis |
author |
Azevedo, Kesley Pablo Morais de |
author_facet |
Azevedo, Kesley Pablo Morais de Oliveira Segundo, Victor Hugo de Medeiros, Gidyenne Christine Bandeira Silva de Mata, Ádala Nayana de Sousa García, Daniel Ángel Leitão, José Carlos Gomes de Carvalho Knackfuss, Maria Irany Piuvezam, Grasiela |
author_role |
author |
author2 |
Oliveira Segundo, Victor Hugo de Medeiros, Gidyenne Christine Bandeira Silva de Mata, Ádala Nayana de Sousa García, Daniel Ángel Leitão, José Carlos Gomes de Carvalho Knackfuss, Maria Irany Piuvezam, Grasiela |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Azevedo, Kesley Pablo Morais de Oliveira Segundo, Victor Hugo de Medeiros, Gidyenne Christine Bandeira Silva de Mata, Ádala Nayana de Sousa García, Daniel Ángel Leitão, José Carlos Gomes de Carvalho Knackfuss, Maria Irany Piuvezam, Grasiela |
dc.subject.por.fl_str_mv |
Adolescent BDNF Executive function Exercise Systematic review |
topic |
Adolescent BDNF Executive function Exercise Systematic review |
description |
Backoground: Evidence available in the literature suggests that physical exercise increases the release of brain-derived neurotrophic factor (BDNF) in humans and may possibly be related to improvements in executive function. However, studies of this phenomenon in adolescents are still scarce. The objective of this work is to describe the protocol for a systematic review (SR) and meta-analysis of interventional studies aiming to determine the effect of physical exercise on BDNF levels and executive function in adolescents. Methods: This protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and by the Cochrane Handbook of Systematic Reviews of Interventions. The databases to be searched are PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, SPORTDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. Interventional studies conducted on adolescents with different exercise protocols and evaluations of BDNF levels and executive function in pre- and post-intervention periods will be included in the systematic review. The characteristics of the studies, participants, and main results will be described, then the evaluation of the risk of biases and the level of evidence obtained by the protocol will be assessed. The selection of studies, data extraction, and evaluation of the methodological quality will be performed by 2 experienced reviewers independently. Conclusion: The systematic review will present the effects of the practice of physical exercises on the BDNF and executive function levels. The results will strengthen the interventions with the focus on the brain health of adolescents through general orientations and the evidences described shall direct future research. PROSPERO registration number: CRD42018110683 Abbreviations: BDNF = brain-derived neurotrophic factor, CPF = prefrontal cortex, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, SR = systematic review |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-07 |
dc.date.accessioned.fl_str_mv |
2021-01-05T13:57:46Z |
dc.date.available.fl_str_mv |
2021-01-05T13:57:46Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
AZEVEDO, Kesley Pablo Morais de; OLIVEIRA SEGUNDO, Victor Hugo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; MATA, Ádala Nayana de Sousa; GARCÍA, Daniel Ángel; LEITÃO, José Carlos Gomes de Carvalho; KNACKFUSS, Maria Irany; PIUVEZAM, Grasiela. Effects of exercise on the levels of BDNF and executive function in adolescents. Medicine, [s. l.], v. 98, n. 28, p. 1-5, jul. 2019. Ovid Technologies (Wolters Kluwer Health). Disponível em: https://journals.lww.com/md-journal/FullText/2019/07120/Effects_of_exercise_on_the_levels_of_BDNF_and.87.aspx. Acesso em: 21 ago. 2020. http://dx.doi.org/10.1097/md.0000000000016445. |
dc.identifier.uri.fl_str_mv |
https://repositorio.ufrn.br/handle/123456789/31181 |
dc.identifier.issn.none.fl_str_mv |
0025-7974 1536-5964 |
dc.identifier.doi.none.fl_str_mv |
10.1097/md.0000000000016445 |
identifier_str_mv |
AZEVEDO, Kesley Pablo Morais de; OLIVEIRA SEGUNDO, Victor Hugo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; MATA, Ádala Nayana de Sousa; GARCÍA, Daniel Ángel; LEITÃO, José Carlos Gomes de Carvalho; KNACKFUSS, Maria Irany; PIUVEZAM, Grasiela. Effects of exercise on the levels of BDNF and executive function in adolescents. Medicine, [s. l.], v. 98, n. 28, p. 1-5, jul. 2019. Ovid Technologies (Wolters Kluwer Health). Disponível em: https://journals.lww.com/md-journal/FullText/2019/07120/Effects_of_exercise_on_the_levels_of_BDNF_and.87.aspx. Acesso em: 21 ago. 2020. http://dx.doi.org/10.1097/md.0000000000016445. 0025-7974 1536-5964 10.1097/md.0000000000016445 |
url |
https://repositorio.ufrn.br/handle/123456789/31181 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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Attribution 3.0 Brazil http://creativecommons.org/licenses/by/3.0/br/ info:eu-repo/semantics/openAccess |
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Attribution 3.0 Brazil http://creativecommons.org/licenses/by/3.0/br/ |
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openAccess |
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Lippincott, Williams & Wilkins |
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Lippincott, Williams & Wilkins |
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