Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis

Detalhes bibliográficos
Autor(a) principal: Azevedo, Kesley Pablo Morais de
Data de Publicação: 2019
Outros Autores: Oliveira Segundo, Victor Hugo de, Medeiros, Gidyenne Christine Bandeira Silva de, Mata, Ádala Nayana de Sousa, García, Daniel Ángel, Leitão, José Carlos Gomes de Carvalho, Knackfuss, Maria Irany, Piuvezam, Grasiela
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFRN
Texto Completo: https://repositorio.ufrn.br/handle/123456789/31181
Resumo: Backoground: Evidence available in the literature suggests that physical exercise increases the release of brain-derived neurotrophic factor (BDNF) in humans and may possibly be related to improvements in executive function. However, studies of this phenomenon in adolescents are still scarce. The objective of this work is to describe the protocol for a systematic review (SR) and meta-analysis of interventional studies aiming to determine the effect of physical exercise on BDNF levels and executive function in adolescents. Methods: This protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and by the Cochrane Handbook of Systematic Reviews of Interventions. The databases to be searched are PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, SPORTDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. Interventional studies conducted on adolescents with different exercise protocols and evaluations of BDNF levels and executive function in pre- and post-intervention periods will be included in the systematic review. The characteristics of the studies, participants, and main results will be described, then the evaluation of the risk of biases and the level of evidence obtained by the protocol will be assessed. The selection of studies, data extraction, and evaluation of the methodological quality will be performed by 2 experienced reviewers independently. Conclusion: The systematic review will present the effects of the practice of physical exercises on the BDNF and executive function levels. The results will strengthen the interventions with the focus on the brain health of adolescents through general orientations and the evidences described shall direct future research. PROSPERO registration number: CRD42018110683 Abbreviations: BDNF = brain-derived neurotrophic factor, CPF = prefrontal cortex, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, SR = systematic review
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spelling Azevedo, Kesley Pablo Morais deOliveira Segundo, Victor Hugo deMedeiros, Gidyenne Christine Bandeira Silva deMata, Ádala Nayana de SousaGarcía, Daniel ÁngelLeitão, José Carlos Gomes de CarvalhoKnackfuss, Maria IranyPiuvezam, Grasiela2021-01-05T13:57:46Z2021-01-05T13:57:46Z2019-07AZEVEDO, Kesley Pablo Morais de; OLIVEIRA SEGUNDO, Victor Hugo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; MATA, Ádala Nayana de Sousa; GARCÍA, Daniel Ángel; LEITÃO, José Carlos Gomes de Carvalho; KNACKFUSS, Maria Irany; PIUVEZAM, Grasiela. Effects of exercise on the levels of BDNF and executive function in adolescents. Medicine, [s. l.], v. 98, n. 28, p. 1-5, jul. 2019. Ovid Technologies (Wolters Kluwer Health). Disponível em: https://journals.lww.com/md-journal/FullText/2019/07120/Effects_of_exercise_on_the_levels_of_BDNF_and.87.aspx. Acesso em: 21 ago. 2020. http://dx.doi.org/10.1097/md.0000000000016445.0025-79741536-5964https://repositorio.ufrn.br/handle/123456789/3118110.1097/md.0000000000016445Lippincott, Williams & WilkinsAttribution 3.0 Brazilhttp://creativecommons.org/licenses/by/3.0/br/info:eu-repo/semantics/openAccessAdolescentBDNFExecutive functionExerciseSystematic reviewEffects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleBackoground: Evidence available in the literature suggests that physical exercise increases the release of brain-derived neurotrophic factor (BDNF) in humans and may possibly be related to improvements in executive function. However, studies of this phenomenon in adolescents are still scarce. The objective of this work is to describe the protocol for a systematic review (SR) and meta-analysis of interventional studies aiming to determine the effect of physical exercise on BDNF levels and executive function in adolescents. Methods: This protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and by the Cochrane Handbook of Systematic Reviews of Interventions. The databases to be searched are PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, SPORTDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. Interventional studies conducted on adolescents with different exercise protocols and evaluations of BDNF levels and executive function in pre- and post-intervention periods will be included in the systematic review. The characteristics of the studies, participants, and main results will be described, then the evaluation of the risk of biases and the level of evidence obtained by the protocol will be assessed. The selection of studies, data extraction, and evaluation of the methodological quality will be performed by 2 experienced reviewers independently. Conclusion: The systematic review will present the effects of the practice of physical exercises on the BDNF and executive function levels. The results will strengthen the interventions with the focus on the brain health of adolescents through general orientations and the evidences described shall direct future research. PROSPERO registration number: CRD42018110683 Abbreviations: BDNF = brain-derived neurotrophic factor, CPF = prefrontal cortex, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, SR = systematic reviewengreponame:Repositório Institucional da UFRNinstname:Universidade Federal do Rio Grande do Norte (UFRN)instacron:UFRNORIGINALEffectsExerciseAdolescents_Mata_2019.pdfEffectsExerciseAdolescents_Mata_2019.pdfapplication/pdf266583https://repositorio.ufrn.br/bitstream/123456789/31181/1/EffectsExerciseAdolescents_Mata_2019.pdf1cac44eac5887fab94767f8d61473e62MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8914https://repositorio.ufrn.br/bitstream/123456789/31181/2/license_rdf4d2950bda3d176f570a9f8b328dfbbefMD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81484https://repositorio.ufrn.br/bitstream/123456789/31181/3/license.txte9597aa2854d128fd968be5edc8a28d9MD53TEXTEffectsExerciseAdolescents_Mata_2019.pdf.txtEffectsExerciseAdolescents_Mata_2019.pdf.txtExtracted texttext/plain23733https://repositorio.ufrn.br/bitstream/123456789/31181/4/EffectsExerciseAdolescents_Mata_2019.pdf.txt69fbd9c1d72bb071084d135653294eecMD54THUMBNAILEffectsExerciseAdolescents_Mata_2019.pdf.jpgEffectsExerciseAdolescents_Mata_2019.pdf.jpgGenerated Thumbnailimage/jpeg1805https://repositorio.ufrn.br/bitstream/123456789/31181/5/EffectsExerciseAdolescents_Mata_2019.pdf.jpg226db4ae6cb8d35dc21fea59fe6343c3MD55123456789/311812021-01-10 04:54:15.994oai:https://repositorio.ufrn.br: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Repositório de PublicaçõesPUBhttp://repositorio.ufrn.br/oai/opendoar:2021-01-10T07:54:15Repositório Institucional da UFRN - Universidade Federal do Rio Grande do Norte (UFRN)false
dc.title.pt_BR.fl_str_mv Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
title Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
spellingShingle Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
Azevedo, Kesley Pablo Morais de
Adolescent
BDNF
Executive function
Exercise
Systematic review
title_short Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
title_full Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
title_fullStr Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
title_full_unstemmed Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
title_sort Effects of exercise on the levels of BDNF and executive function in adolescents: a protocol for systematic review and meta-analysis
author Azevedo, Kesley Pablo Morais de
author_facet Azevedo, Kesley Pablo Morais de
Oliveira Segundo, Victor Hugo de
Medeiros, Gidyenne Christine Bandeira Silva de
Mata, Ádala Nayana de Sousa
García, Daniel Ángel
Leitão, José Carlos Gomes de Carvalho
Knackfuss, Maria Irany
Piuvezam, Grasiela
author_role author
author2 Oliveira Segundo, Victor Hugo de
Medeiros, Gidyenne Christine Bandeira Silva de
Mata, Ádala Nayana de Sousa
García, Daniel Ángel
Leitão, José Carlos Gomes de Carvalho
Knackfuss, Maria Irany
Piuvezam, Grasiela
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Azevedo, Kesley Pablo Morais de
Oliveira Segundo, Victor Hugo de
Medeiros, Gidyenne Christine Bandeira Silva de
Mata, Ádala Nayana de Sousa
García, Daniel Ángel
Leitão, José Carlos Gomes de Carvalho
Knackfuss, Maria Irany
Piuvezam, Grasiela
dc.subject.por.fl_str_mv Adolescent
BDNF
Executive function
Exercise
Systematic review
topic Adolescent
BDNF
Executive function
Exercise
Systematic review
description Backoground: Evidence available in the literature suggests that physical exercise increases the release of brain-derived neurotrophic factor (BDNF) in humans and may possibly be related to improvements in executive function. However, studies of this phenomenon in adolescents are still scarce. The objective of this work is to describe the protocol for a systematic review (SR) and meta-analysis of interventional studies aiming to determine the effect of physical exercise on BDNF levels and executive function in adolescents. Methods: This protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and by the Cochrane Handbook of Systematic Reviews of Interventions. The databases to be searched are PubMed, EMBASE, Scopus, ScienceDirect, Web of Science, SPORTDiscus, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL. Interventional studies conducted on adolescents with different exercise protocols and evaluations of BDNF levels and executive function in pre- and post-intervention periods will be included in the systematic review. The characteristics of the studies, participants, and main results will be described, then the evaluation of the risk of biases and the level of evidence obtained by the protocol will be assessed. The selection of studies, data extraction, and evaluation of the methodological quality will be performed by 2 experienced reviewers independently. Conclusion: The systematic review will present the effects of the practice of physical exercises on the BDNF and executive function levels. The results will strengthen the interventions with the focus on the brain health of adolescents through general orientations and the evidences described shall direct future research. PROSPERO registration number: CRD42018110683 Abbreviations: BDNF = brain-derived neurotrophic factor, CPF = prefrontal cortex, GRADE = Grading of Recommendations Assessment, Development, and Evaluation, PRISMA-P = Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols, SR = systematic review
publishDate 2019
dc.date.issued.fl_str_mv 2019-07
dc.date.accessioned.fl_str_mv 2021-01-05T13:57:46Z
dc.date.available.fl_str_mv 2021-01-05T13:57:46Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv AZEVEDO, Kesley Pablo Morais de; OLIVEIRA SEGUNDO, Victor Hugo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; MATA, Ádala Nayana de Sousa; GARCÍA, Daniel Ángel; LEITÃO, José Carlos Gomes de Carvalho; KNACKFUSS, Maria Irany; PIUVEZAM, Grasiela. Effects of exercise on the levels of BDNF and executive function in adolescents. Medicine, [s. l.], v. 98, n. 28, p. 1-5, jul. 2019. Ovid Technologies (Wolters Kluwer Health). Disponível em: https://journals.lww.com/md-journal/FullText/2019/07120/Effects_of_exercise_on_the_levels_of_BDNF_and.87.aspx. Acesso em: 21 ago. 2020. http://dx.doi.org/10.1097/md.0000000000016445.
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1536-5964
dc.identifier.doi.none.fl_str_mv 10.1097/md.0000000000016445
identifier_str_mv AZEVEDO, Kesley Pablo Morais de; OLIVEIRA SEGUNDO, Victor Hugo de; MEDEIROS, Gidyenne Christine Bandeira Silva de; MATA, Ádala Nayana de Sousa; GARCÍA, Daniel Ángel; LEITÃO, José Carlos Gomes de Carvalho; KNACKFUSS, Maria Irany; PIUVEZAM, Grasiela. Effects of exercise on the levels of BDNF and executive function in adolescents. Medicine, [s. l.], v. 98, n. 28, p. 1-5, jul. 2019. Ovid Technologies (Wolters Kluwer Health). Disponível em: https://journals.lww.com/md-journal/FullText/2019/07120/Effects_of_exercise_on_the_levels_of_BDNF_and.87.aspx. Acesso em: 21 ago. 2020. http://dx.doi.org/10.1097/md.0000000000016445.
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