FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG

Detalhes bibliográficos
Autor(a) principal: Mello, Sheila Santana de
Data de Publicação: 2024
Outros Autores: Vasconcelos, Lídia Maria Amaro, Milken, Vanessa Martins Fayad, Mota, Francisco Claudio Dantas, Medeiros-Ronchi, Alessandra Aparecida
Tipo de documento: Artigo
Idioma: por
Título da fonte: Medicina Veterinária (Recife. Online)
Texto Completo: https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176
Resumo: Osteomyelitis is a severe systemic infectious disease characterized by destructive and progressive bone inflammation, which is usually bacterial in origin, and occasionally viral or fungal. The objective was to report the case of a dog with fungal osteomyelitis, detailing the diagnosis and treatment evolution. A male, crossbreed dog, four months old, was treated at the Veterinary Hospital of the Federal University of Uberlândia (HOVET-UFU), presenting hyperthermia, hyporexia, reactive lymph nodes, lameness and open wound in the right forelimb (RF), in addition to secretion purulent and exposed bone. The radiograph showed Salter Harris I fractures in the physeal cartilages of the right ulna and signs of aggressive polyostotic bone lesion in RF. Fungal and bacterial cultures isolated Enterococcus sp., Penicillium sp. and Acremonium sp. The diagnosis obtained was fungal osteomyelitis. Based on the antibiogram and antifungigram, the drugs amoxicillin with potassium clavulanate, omeprazole and itraconazole were used and the animal was radiographically monitored every 30 days. After 150 days, signs of bone remodeling in the joint and adjacent bones were more evident and the treatment was terminated. The dog presented 28 months free of relapses. It should be noted that the medical management of a wound should not be directed solely at healing, requiring radiography and, in cases of suspected osteomyelitis, tests to exclude differential diagnoses, as well as to choose the most suitable drug, effective in each case.
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spelling FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOGOsteomielite fúngica causada por Penicillium sp. e Acremonium sp. em um cãocaninoosteopatiafungoitraconazolradiografiaCanine; Osteopathy; Fungus; Itraconazole; RadiographyOsteomyelitis is a severe systemic infectious disease characterized by destructive and progressive bone inflammation, which is usually bacterial in origin, and occasionally viral or fungal. The objective was to report the case of a dog with fungal osteomyelitis, detailing the diagnosis and treatment evolution. A male, crossbreed dog, four months old, was treated at the Veterinary Hospital of the Federal University of Uberlândia (HOVET-UFU), presenting hyperthermia, hyporexia, reactive lymph nodes, lameness and open wound in the right forelimb (RF), in addition to secretion purulent and exposed bone. The radiograph showed Salter Harris I fractures in the physeal cartilages of the right ulna and signs of aggressive polyostotic bone lesion in RF. Fungal and bacterial cultures isolated Enterococcus sp., Penicillium sp. and Acremonium sp. The diagnosis obtained was fungal osteomyelitis. Based on the antibiogram and antifungigram, the drugs amoxicillin with potassium clavulanate, omeprazole and itraconazole were used and the animal was radiographically monitored every 30 days. After 150 days, signs of bone remodeling in the joint and adjacent bones were more evident and the treatment was terminated. The dog presented 28 months free of relapses. It should be noted that the medical management of a wound should not be directed solely at healing, requiring radiography and, in cases of suspected osteomyelitis, tests to exclude differential diagnoses, as well as to choose the most suitable drug, effective in each case.A osteomielite é uma doença infecciosa sistêmica grave, caracterizada pela inflamação óssea destrutiva e progressiva, que geralmente possui origem bacteriana, e, ocasionalmente, viral ou fúngica. Objetivou-se relatar o caso de um cão com osteomielite fúngica, detalhando o diagnóstico e a evolução do tratamento. Foi atendido no Hospital Veterinário da Universidade Federal de Uberlândia (HOVET-UFU) um cão, macho, 8,9 kg, mestiço, quatro meses de idade, apresentando hipertermia, hiporexia, linfonodos reativos, claudicação e ferida aberta em membro torácico direito (MTD), além de secreção purulenta e exposição óssea. A radiografia evidenciou fraturas Salter Harris I em cartilagens fisárias da ulna direita e sinais de lesão óssea agressiva poliostótica em MTD. As culturas fúngica e bacteriana isolaram Enterococcus sp., Penicillium sp. e Acremonium sp. O diagnóstico obtido foi osteomielite fúngica. Com base no antibiograma e antifungigrama, foram utilizados os fármacos amoxicilina com clavulanato de potássio, omeprazol e itraconazol e o animal foi acompanhado radiograficamente a cada 30 dias. Após 150 dias os sinais de remodelamento ósseo da articulação e ossos adjacentes eram mais evidentes e o tratamento foi finalizado. O cão permaneceu por 28 meses livre de recidivas. Ressalta-se que a conduta médica diante de uma ferida não deve ser direcionada somente à cicatrização, sendo necessária a realização de radiografia e, em casos de suspeita de osteomielite, exames para exclusão dos diagnósticos diferenciais, bem como, para a escolha do fármaco mais eficaz em cada caso.MEDICINA VETERINÁRIA2024-05-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/617610.26605/medvet-v18n1-6176Medicina Veterinária; v. 18 n. 1 (2024): Medicina Veterinária; 15-212675-66171809-467810.26605/medvet-v18n1reponame:Medicina Veterinária (Recife. Online)instname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEporhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176/482485269Copyright (c) 2024 Sheila Santana de Mello, Lídia Maria Amaro Vasconcelos, Vanessa Martins Fayad Milken, Francisco Claudio Dantas Mota, Alessandra Aparecida Medeiros-Ronchihttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessMello, Sheila Santana de Vasconcelos, Lídia Maria AmaroMilken, Vanessa Martins FayadMota, Francisco Claudio DantasMedeiros-Ronchi, Alessandra Aparecida2024-05-23T18:35:27Zoai:ojs.10.0.7.8:article/6176Revistahttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/PUBhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/oairevmedvet@ufrpe.br1809-46782675-6617opendoar:2024-05-23T18:35:27Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)false
dc.title.none.fl_str_mv FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
Osteomielite fúngica causada por Penicillium sp. e Acremonium sp. em um cão
title FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
spellingShingle FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
Mello, Sheila Santana de
canino
osteopatia
fungo
itraconazol
radiografia
Canine; Osteopathy; Fungus; Itraconazole; Radiography
title_short FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
title_full FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
title_fullStr FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
title_full_unstemmed FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
title_sort FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
author Mello, Sheila Santana de
author_facet Mello, Sheila Santana de
Vasconcelos, Lídia Maria Amaro
Milken, Vanessa Martins Fayad
Mota, Francisco Claudio Dantas
Medeiros-Ronchi, Alessandra Aparecida
author_role author
author2 Vasconcelos, Lídia Maria Amaro
Milken, Vanessa Martins Fayad
Mota, Francisco Claudio Dantas
Medeiros-Ronchi, Alessandra Aparecida
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Mello, Sheila Santana de
Vasconcelos, Lídia Maria Amaro
Milken, Vanessa Martins Fayad
Mota, Francisco Claudio Dantas
Medeiros-Ronchi, Alessandra Aparecida
dc.subject.por.fl_str_mv canino
osteopatia
fungo
itraconazol
radiografia
Canine; Osteopathy; Fungus; Itraconazole; Radiography
topic canino
osteopatia
fungo
itraconazol
radiografia
Canine; Osteopathy; Fungus; Itraconazole; Radiography
description Osteomyelitis is a severe systemic infectious disease characterized by destructive and progressive bone inflammation, which is usually bacterial in origin, and occasionally viral or fungal. The objective was to report the case of a dog with fungal osteomyelitis, detailing the diagnosis and treatment evolution. A male, crossbreed dog, four months old, was treated at the Veterinary Hospital of the Federal University of Uberlândia (HOVET-UFU), presenting hyperthermia, hyporexia, reactive lymph nodes, lameness and open wound in the right forelimb (RF), in addition to secretion purulent and exposed bone. The radiograph showed Salter Harris I fractures in the physeal cartilages of the right ulna and signs of aggressive polyostotic bone lesion in RF. Fungal and bacterial cultures isolated Enterococcus sp., Penicillium sp. and Acremonium sp. The diagnosis obtained was fungal osteomyelitis. Based on the antibiogram and antifungigram, the drugs amoxicillin with potassium clavulanate, omeprazole and itraconazole were used and the animal was radiographically monitored every 30 days. After 150 days, signs of bone remodeling in the joint and adjacent bones were more evident and the treatment was terminated. The dog presented 28 months free of relapses. It should be noted that the medical management of a wound should not be directed solely at healing, requiring radiography and, in cases of suspected osteomyelitis, tests to exclude differential diagnoses, as well as to choose the most suitable drug, effective in each case.
publishDate 2024
dc.date.none.fl_str_mv 2024-05-23
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info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176
10.26605/medvet-v18n1-6176
url https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176
identifier_str_mv 10.26605/medvet-v18n1-6176
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176/482485269
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MEDICINA VETERINÁRIA
publisher.none.fl_str_mv MEDICINA VETERINÁRIA
dc.source.none.fl_str_mv Medicina Veterinária; v. 18 n. 1 (2024): Medicina Veterinária; 15-21
2675-6617
1809-4678
10.26605/medvet-v18n1
reponame:Medicina Veterinária (Recife. Online)
instname:Universidade Federal Rural de Pernambuco (UFRPE)
instacron:UFRPE
instname_str Universidade Federal Rural de Pernambuco (UFRPE)
instacron_str UFRPE
institution UFRPE
reponame_str Medicina Veterinária (Recife. Online)
collection Medicina Veterinária (Recife. Online)
repository.name.fl_str_mv Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)
repository.mail.fl_str_mv revmedvet@ufrpe.br
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