FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Medicina Veterinária (Recife. Online) |
Texto Completo: | https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176 |
Resumo: | Osteomyelitis is a severe systemic infectious disease characterized by destructive and progressive bone inflammation, which is usually bacterial in origin, and occasionally viral or fungal. The objective was to report the case of a dog with fungal osteomyelitis, detailing the diagnosis and treatment evolution. A male, crossbreed dog, four months old, was treated at the Veterinary Hospital of the Federal University of Uberlândia (HOVET-UFU), presenting hyperthermia, hyporexia, reactive lymph nodes, lameness and open wound in the right forelimb (RF), in addition to secretion purulent and exposed bone. The radiograph showed Salter Harris I fractures in the physeal cartilages of the right ulna and signs of aggressive polyostotic bone lesion in RF. Fungal and bacterial cultures isolated Enterococcus sp., Penicillium sp. and Acremonium sp. The diagnosis obtained was fungal osteomyelitis. Based on the antibiogram and antifungigram, the drugs amoxicillin with potassium clavulanate, omeprazole and itraconazole were used and the animal was radiographically monitored every 30 days. After 150 days, signs of bone remodeling in the joint and adjacent bones were more evident and the treatment was terminated. The dog presented 28 months free of relapses. It should be noted that the medical management of a wound should not be directed solely at healing, requiring radiography and, in cases of suspected osteomyelitis, tests to exclude differential diagnoses, as well as to choose the most suitable drug, effective in each case. |
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FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOGOsteomielite fúngica causada por Penicillium sp. e Acremonium sp. em um cãocaninoosteopatiafungoitraconazolradiografiaCanine; Osteopathy; Fungus; Itraconazole; RadiographyOsteomyelitis is a severe systemic infectious disease characterized by destructive and progressive bone inflammation, which is usually bacterial in origin, and occasionally viral or fungal. The objective was to report the case of a dog with fungal osteomyelitis, detailing the diagnosis and treatment evolution. A male, crossbreed dog, four months old, was treated at the Veterinary Hospital of the Federal University of Uberlândia (HOVET-UFU), presenting hyperthermia, hyporexia, reactive lymph nodes, lameness and open wound in the right forelimb (RF), in addition to secretion purulent and exposed bone. The radiograph showed Salter Harris I fractures in the physeal cartilages of the right ulna and signs of aggressive polyostotic bone lesion in RF. Fungal and bacterial cultures isolated Enterococcus sp., Penicillium sp. and Acremonium sp. The diagnosis obtained was fungal osteomyelitis. Based on the antibiogram and antifungigram, the drugs amoxicillin with potassium clavulanate, omeprazole and itraconazole were used and the animal was radiographically monitored every 30 days. After 150 days, signs of bone remodeling in the joint and adjacent bones were more evident and the treatment was terminated. The dog presented 28 months free of relapses. It should be noted that the medical management of a wound should not be directed solely at healing, requiring radiography and, in cases of suspected osteomyelitis, tests to exclude differential diagnoses, as well as to choose the most suitable drug, effective in each case.A osteomielite é uma doença infecciosa sistêmica grave, caracterizada pela inflamação óssea destrutiva e progressiva, que geralmente possui origem bacteriana, e, ocasionalmente, viral ou fúngica. Objetivou-se relatar o caso de um cão com osteomielite fúngica, detalhando o diagnóstico e a evolução do tratamento. Foi atendido no Hospital Veterinário da Universidade Federal de Uberlândia (HOVET-UFU) um cão, macho, 8,9 kg, mestiço, quatro meses de idade, apresentando hipertermia, hiporexia, linfonodos reativos, claudicação e ferida aberta em membro torácico direito (MTD), além de secreção purulenta e exposição óssea. A radiografia evidenciou fraturas Salter Harris I em cartilagens fisárias da ulna direita e sinais de lesão óssea agressiva poliostótica em MTD. As culturas fúngica e bacteriana isolaram Enterococcus sp., Penicillium sp. e Acremonium sp. O diagnóstico obtido foi osteomielite fúngica. Com base no antibiograma e antifungigrama, foram utilizados os fármacos amoxicilina com clavulanato de potássio, omeprazol e itraconazol e o animal foi acompanhado radiograficamente a cada 30 dias. Após 150 dias os sinais de remodelamento ósseo da articulação e ossos adjacentes eram mais evidentes e o tratamento foi finalizado. O cão permaneceu por 28 meses livre de recidivas. Ressalta-se que a conduta médica diante de uma ferida não deve ser direcionada somente à cicatrização, sendo necessária a realização de radiografia e, em casos de suspeita de osteomielite, exames para exclusão dos diagnósticos diferenciais, bem como, para a escolha do fármaco mais eficaz em cada caso.MEDICINA VETERINÁRIA2024-05-23info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/617610.26605/medvet-v18n1-6176Medicina Veterinária; v. 18 n. 1 (2024): Medicina Veterinária; 15-212675-66171809-467810.26605/medvet-v18n1reponame:Medicina Veterinária (Recife. Online)instname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEporhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176/482485269Copyright (c) 2024 Sheila Santana de Mello, Lídia Maria Amaro Vasconcelos, Vanessa Martins Fayad Milken, Francisco Claudio Dantas Mota, Alessandra Aparecida Medeiros-Ronchihttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessMello, Sheila Santana de Vasconcelos, Lídia Maria AmaroMilken, Vanessa Martins FayadMota, Francisco Claudio DantasMedeiros-Ronchi, Alessandra Aparecida2024-05-23T18:35:27Zoai:ojs.10.0.7.8:article/6176Revistahttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/PUBhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/oairevmedvet@ufrpe.br1809-46782675-6617opendoar:2024-05-23T18:35:27Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)false |
dc.title.none.fl_str_mv |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG Osteomielite fúngica causada por Penicillium sp. e Acremonium sp. em um cão |
title |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG |
spellingShingle |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG Mello, Sheila Santana de canino osteopatia fungo itraconazol radiografia Canine; Osteopathy; Fungus; Itraconazole; Radiography |
title_short |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG |
title_full |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG |
title_fullStr |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG |
title_full_unstemmed |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG |
title_sort |
FUNGAL OSTEOMYELITIS CAUSED BY Penicillium sp. AND Acremonium sp. IN A DOG |
author |
Mello, Sheila Santana de |
author_facet |
Mello, Sheila Santana de Vasconcelos, Lídia Maria Amaro Milken, Vanessa Martins Fayad Mota, Francisco Claudio Dantas Medeiros-Ronchi, Alessandra Aparecida |
author_role |
author |
author2 |
Vasconcelos, Lídia Maria Amaro Milken, Vanessa Martins Fayad Mota, Francisco Claudio Dantas Medeiros-Ronchi, Alessandra Aparecida |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Mello, Sheila Santana de Vasconcelos, Lídia Maria Amaro Milken, Vanessa Martins Fayad Mota, Francisco Claudio Dantas Medeiros-Ronchi, Alessandra Aparecida |
dc.subject.por.fl_str_mv |
canino osteopatia fungo itraconazol radiografia Canine; Osteopathy; Fungus; Itraconazole; Radiography |
topic |
canino osteopatia fungo itraconazol radiografia Canine; Osteopathy; Fungus; Itraconazole; Radiography |
description |
Osteomyelitis is a severe systemic infectious disease characterized by destructive and progressive bone inflammation, which is usually bacterial in origin, and occasionally viral or fungal. The objective was to report the case of a dog with fungal osteomyelitis, detailing the diagnosis and treatment evolution. A male, crossbreed dog, four months old, was treated at the Veterinary Hospital of the Federal University of Uberlândia (HOVET-UFU), presenting hyperthermia, hyporexia, reactive lymph nodes, lameness and open wound in the right forelimb (RF), in addition to secretion purulent and exposed bone. The radiograph showed Salter Harris I fractures in the physeal cartilages of the right ulna and signs of aggressive polyostotic bone lesion in RF. Fungal and bacterial cultures isolated Enterococcus sp., Penicillium sp. and Acremonium sp. The diagnosis obtained was fungal osteomyelitis. Based on the antibiogram and antifungigram, the drugs amoxicillin with potassium clavulanate, omeprazole and itraconazole were used and the animal was radiographically monitored every 30 days. After 150 days, signs of bone remodeling in the joint and adjacent bones were more evident and the treatment was terminated. The dog presented 28 months free of relapses. It should be noted that the medical management of a wound should not be directed solely at healing, requiring radiography and, in cases of suspected osteomyelitis, tests to exclude differential diagnoses, as well as to choose the most suitable drug, effective in each case. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-05-23 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176 10.26605/medvet-v18n1-6176 |
url |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176 |
identifier_str_mv |
10.26605/medvet-v18n1-6176 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6176/482485269 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MEDICINA VETERINÁRIA |
publisher.none.fl_str_mv |
MEDICINA VETERINÁRIA |
dc.source.none.fl_str_mv |
Medicina Veterinária; v. 18 n. 1 (2024): Medicina Veterinária; 15-21 2675-6617 1809-4678 10.26605/medvet-v18n1 reponame:Medicina Veterinária (Recife. Online) instname:Universidade Federal Rural de Pernambuco (UFRPE) instacron:UFRPE |
instname_str |
Universidade Federal Rural de Pernambuco (UFRPE) |
instacron_str |
UFRPE |
institution |
UFRPE |
reponame_str |
Medicina Veterinária (Recife. Online) |
collection |
Medicina Veterinária (Recife. Online) |
repository.name.fl_str_mv |
Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE) |
repository.mail.fl_str_mv |
revmedvet@ufrpe.br |
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1806552252361474048 |