Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
Autor(a) principal: | |
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Data de Publicação: | 2024 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Medicina Veterinária (Recife. Online) |
Texto Completo: | https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004 |
Resumo: | Diabetes insipidus (DI) is an infrequent endocrine disorder in cats caused by alteration in the synthesis and/or secretion of antidiuretic hormone (ADH), or by renal tubular inability to respond to the hormone. This endocrine disorder can have varied origins. The aim of this article was to report a case of diabetes insipidus in a 5-year-old mixed breed female cat, complaining of polyuria (PU) and polydipsia (PD), initially diagnosed as chronic kidney disease (CKD). The patient had already been evaluated by a professional, who found anemia, dehydration, azotemia and ultrasound changes suggestive of acute renal failure. Due to the concern of the owner, the patient was evaluated for another professional that observed a history, previous laboratory tests, and it was observed that the animal had a satisfactory body score, normal colored and hydrated mucous membranes, presence of gingivitis in the molar and premolar teeth, and moderate halitosis. The urinalysis showed isosthenuria, with no other alterations in the urinary analytes. Ultrasound examinations revealed maintenance of the corticomedullary architecture, discreet points of cortical mineralization and discreet dilation of the renal pelvis. The differentials of diabetes mellitus and hyperthyroidism were ruled out. Based on the clinical condition, diabetes insipidus was suspected, and the diagnosis was confirmed after a positive response to the use of desmopressin by the conjunctival route and increased urinary density. |
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Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiologyDiagnóstico presuntivo de diabetes insipidus felinadesmopressinhyposthenuriaantidiuretic hormonespolydipsiapolyuriadesmopressinahipostenúriahormônio antidiuréticopolidipsiapoliúriaDiabetes insipidus (DI) is an infrequent endocrine disorder in cats caused by alteration in the synthesis and/or secretion of antidiuretic hormone (ADH), or by renal tubular inability to respond to the hormone. This endocrine disorder can have varied origins. The aim of this article was to report a case of diabetes insipidus in a 5-year-old mixed breed female cat, complaining of polyuria (PU) and polydipsia (PD), initially diagnosed as chronic kidney disease (CKD). The patient had already been evaluated by a professional, who found anemia, dehydration, azotemia and ultrasound changes suggestive of acute renal failure. Due to the concern of the owner, the patient was evaluated for another professional that observed a history, previous laboratory tests, and it was observed that the animal had a satisfactory body score, normal colored and hydrated mucous membranes, presence of gingivitis in the molar and premolar teeth, and moderate halitosis. The urinalysis showed isosthenuria, with no other alterations in the urinary analytes. Ultrasound examinations revealed maintenance of the corticomedullary architecture, discreet points of cortical mineralization and discreet dilation of the renal pelvis. The differentials of diabetes mellitus and hyperthyroidism were ruled out. Based on the clinical condition, diabetes insipidus was suspected, and the diagnosis was confirmed after a positive response to the use of desmopressin by the conjunctival route and increased urinary density.Diabetes insipidus (DI) é um distúrbio endócrino infrequente em gatos causado pela alteração na síntese e/ou secreção do hormônio antidiurético, ou pela incapacidade tubular renal em responder ao hormônio. Essa desordem pode ter origens variadas. Objetivou-se relatar um caso de diabetes insipidus em uma gata, sem raça definida, de cinco anos, com queixa de poliúria e polidipsia, inicialmente diagnosticada como doente renal crônica. A paciente já havia sido avaliada por outro profissional, o qual constatou anemia, desidratação, azotemia e alterações ultrassonográficas sugestivas de injúria renal aguda. Mediante a preocupação do tutor e a pedido do outro profissional, a paciente foi encaminhada para nova avaliação com histórico e os resultados do exame físico anterior para um atendimento especializado em felinos. Observou-se que o animal apresentava escore corporal satisfatório, mucosas normocoradas e hidratadas, presença de gengivite nos dentes molares e pré-molares, e halitose moderada. No exame de urinálise foi constatada isostenúria, sem demais alterações nos analitos urinários. Exames de ultrassonografia revelaram manutenção da arquitetura corticomedular, discretos pontos de mineralização cortical e discreta dilatação de pelve renal. Os diferenciais de diabetes mellitus e hipertireoidismo foram descartados. Mediante o quadro clínico, suspeitou-se de DI, sendo o diagnóstico confirmado após resposta positiva ao uso de desmopressina pela via conjuntival e elevação da densidade urinária.MEDICINA VETERINÁRIA2024-08-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/600410.26605/medvet-v18n2-6004Medicina Veterinária; v. 18 n. 2 (2024): Medicina Veterinária; 138-1422675-66171809-467810.26605/medvet-v18n2reponame:Medicina Veterinária (Recife. Online)instname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEporhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004/482485327Copyright (c) 2024 Alisson Paulo da Silva, Felipe Gaia de Sousa, Jennifer Aragão da Silva, Jéssica Ragazzi Calesso, Suzane Lilian Beierhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessda Silva, Alisson Paulode Sousa, Felipe Gaiada Silva, Jennifer AragãoCalesso, Jéssica RagazziBeier, Suzane Lilian2024-08-02T14:03:50Zoai:ojs.10.0.7.8:article/6004Revistahttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/PUBhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/oairevmedvet@ufrpe.br1809-46782675-6617opendoar:2024-08-02T14:03:50Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)false |
dc.title.none.fl_str_mv |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology Diagnóstico presuntivo de diabetes insipidus felina |
title |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology |
spellingShingle |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology da Silva, Alisson Paulo desmopressin hyposthenuria antidiuretic hormones polydipsia polyuria desmopressina hipostenúria hormônio antidiurético polidipsia poliúria |
title_short |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology |
title_full |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology |
title_fullStr |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology |
title_full_unstemmed |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology |
title_sort |
Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology |
author |
da Silva, Alisson Paulo |
author_facet |
da Silva, Alisson Paulo de Sousa, Felipe Gaia da Silva, Jennifer Aragão Calesso, Jéssica Ragazzi Beier, Suzane Lilian |
author_role |
author |
author2 |
de Sousa, Felipe Gaia da Silva, Jennifer Aragão Calesso, Jéssica Ragazzi Beier, Suzane Lilian |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
da Silva, Alisson Paulo de Sousa, Felipe Gaia da Silva, Jennifer Aragão Calesso, Jéssica Ragazzi Beier, Suzane Lilian |
dc.subject.por.fl_str_mv |
desmopressin hyposthenuria antidiuretic hormones polydipsia polyuria desmopressina hipostenúria hormônio antidiurético polidipsia poliúria |
topic |
desmopressin hyposthenuria antidiuretic hormones polydipsia polyuria desmopressina hipostenúria hormônio antidiurético polidipsia poliúria |
description |
Diabetes insipidus (DI) is an infrequent endocrine disorder in cats caused by alteration in the synthesis and/or secretion of antidiuretic hormone (ADH), or by renal tubular inability to respond to the hormone. This endocrine disorder can have varied origins. The aim of this article was to report a case of diabetes insipidus in a 5-year-old mixed breed female cat, complaining of polyuria (PU) and polydipsia (PD), initially diagnosed as chronic kidney disease (CKD). The patient had already been evaluated by a professional, who found anemia, dehydration, azotemia and ultrasound changes suggestive of acute renal failure. Due to the concern of the owner, the patient was evaluated for another professional that observed a history, previous laboratory tests, and it was observed that the animal had a satisfactory body score, normal colored and hydrated mucous membranes, presence of gingivitis in the molar and premolar teeth, and moderate halitosis. The urinalysis showed isosthenuria, with no other alterations in the urinary analytes. Ultrasound examinations revealed maintenance of the corticomedullary architecture, discreet points of cortical mineralization and discreet dilation of the renal pelvis. The differentials of diabetes mellitus and hyperthyroidism were ruled out. Based on the clinical condition, diabetes insipidus was suspected, and the diagnosis was confirmed after a positive response to the use of desmopressin by the conjunctival route and increased urinary density. |
publishDate |
2024 |
dc.date.none.fl_str_mv |
2024-08-02 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004 10.26605/medvet-v18n2-6004 |
url |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004 |
identifier_str_mv |
10.26605/medvet-v18n2-6004 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004/482485327 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by-nc-sa/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MEDICINA VETERINÁRIA |
publisher.none.fl_str_mv |
MEDICINA VETERINÁRIA |
dc.source.none.fl_str_mv |
Medicina Veterinária; v. 18 n. 2 (2024): Medicina Veterinária; 138-142 2675-6617 1809-4678 10.26605/medvet-v18n2 reponame:Medicina Veterinária (Recife. Online) instname:Universidade Federal Rural de Pernambuco (UFRPE) instacron:UFRPE |
instname_str |
Universidade Federal Rural de Pernambuco (UFRPE) |
instacron_str |
UFRPE |
institution |
UFRPE |
reponame_str |
Medicina Veterinária (Recife. Online) |
collection |
Medicina Veterinária (Recife. Online) |
repository.name.fl_str_mv |
Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE) |
repository.mail.fl_str_mv |
revmedvet@ufrpe.br |
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1806552252341551104 |