Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology

Detalhes bibliográficos
Autor(a) principal: da Silva, Alisson Paulo
Data de Publicação: 2024
Outros Autores: de Sousa, Felipe Gaia, da Silva, Jennifer Aragão, Calesso, Jéssica Ragazzi, Beier, Suzane Lilian
Tipo de documento: Artigo
Idioma: por
Título da fonte: Medicina Veterinária (Recife. Online)
Texto Completo: https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004
Resumo: Diabetes insipidus (DI) is an infrequent endocrine disorder in cats caused by alteration in the synthesis and/or secretion of antidiuretic hormone (ADH), or by renal tubular inability to respond to the hormone. This endocrine disorder can have varied origins. The aim of this article was to report a case of diabetes insipidus in a 5-year-old mixed breed female cat, complaining of polyuria (PU) and polydipsia (PD), initially diagnosed as chronic kidney disease (CKD). The patient had already been evaluated by a professional, who found anemia, dehydration, azotemia and ultrasound changes suggestive of acute renal failure. Due to the concern of the owner, the patient was evaluated for another professional that observed a history, previous laboratory tests, and it was observed that the animal had a satisfactory body score, normal colored and hydrated mucous membranes, presence of gingivitis in the molar and premolar teeth, and moderate halitosis. The urinalysis showed isosthenuria, with no other alterations in the urinary analytes. Ultrasound examinations revealed maintenance of the corticomedullary architecture, discreet points of cortical mineralization and discreet dilation of the renal pelvis. The differentials of diabetes mellitus and hyperthyroidism were ruled out. Based on the clinical condition, diabetes insipidus was suspected, and the diagnosis was confirmed after a positive response to the use of desmopressin by the conjunctival route and increased urinary density.
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spelling Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiologyDiagnóstico presuntivo de diabetes insipidus felinadesmopressinhyposthenuriaantidiuretic hormonespolydipsiapolyuriadesmopressinahipostenúriahormônio antidiuréticopolidipsiapoliúriaDiabetes insipidus (DI) is an infrequent endocrine disorder in cats caused by alteration in the synthesis and/or secretion of antidiuretic hormone (ADH), or by renal tubular inability to respond to the hormone. This endocrine disorder can have varied origins. The aim of this article was to report a case of diabetes insipidus in a 5-year-old mixed breed female cat, complaining of polyuria (PU) and polydipsia (PD), initially diagnosed as chronic kidney disease (CKD). The patient had already been evaluated by a professional, who found anemia, dehydration, azotemia and ultrasound changes suggestive of acute renal failure. Due to the concern of the owner, the patient was evaluated for another professional that observed a history, previous laboratory tests, and it was observed that the animal had a satisfactory body score, normal colored and hydrated mucous membranes, presence of gingivitis in the molar and premolar teeth, and moderate halitosis. The urinalysis showed isosthenuria, with no other alterations in the urinary analytes. Ultrasound examinations revealed maintenance of the corticomedullary architecture, discreet points of cortical mineralization and discreet dilation of the renal pelvis. The differentials of diabetes mellitus and hyperthyroidism were ruled out. Based on the clinical condition, diabetes insipidus was suspected, and the diagnosis was confirmed after a positive response to the use of desmopressin by the conjunctival route and increased urinary density.Diabetes insipidus (DI) é um distúrbio endócrino infrequente em gatos causado pela alteração na síntese e/ou secreção do hormônio antidiurético, ou pela incapacidade tubular renal em responder ao hormônio. Essa desordem pode ter origens variadas. Objetivou-se relatar um caso de diabetes insipidus em uma gata, sem raça definida, de cinco anos, com queixa de poliúria e polidipsia, inicialmente diagnosticada como doente renal crônica. A paciente já havia sido avaliada por outro profissional, o qual constatou anemia, desidratação, azotemia e alterações ultrassonográficas sugestivas de injúria renal aguda. Mediante a preocupação do tutor e a pedido do outro profissional, a paciente foi encaminhada para nova avaliação com histórico e os resultados do exame físico anterior para um atendimento especializado em felinos. Observou-se que o animal apresentava escore corporal satisfatório, mucosas normocoradas e hidratadas, presença de gengivite nos dentes molares e pré-molares, e halitose moderada. No exame de urinálise foi constatada isostenúria, sem demais alterações nos analitos urinários. Exames de ultrassonografia revelaram manutenção da arquitetura corticomedular, discretos pontos de mineralização cortical e discreta dilatação de pelve renal. Os diferenciais de diabetes mellitus e hipertireoidismo foram descartados. Mediante o quadro clínico, suspeitou-se de DI, sendo o diagnóstico confirmado após resposta positiva ao uso de desmopressina pela via conjuntival e elevação da densidade urinária.MEDICINA VETERINÁRIA2024-08-02info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/600410.26605/medvet-v18n2-6004Medicina Veterinária; v. 18 n. 2 (2024): Medicina Veterinária; 138-1422675-66171809-467810.26605/medvet-v18n2reponame:Medicina Veterinária (Recife. Online)instname:Universidade Federal Rural de Pernambuco (UFRPE)instacron:UFRPEporhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004/482485327Copyright (c) 2024 Alisson Paulo da Silva, Felipe Gaia de Sousa, Jennifer Aragão da Silva, Jéssica Ragazzi Calesso, Suzane Lilian Beierhttps://creativecommons.org/licenses/by-nc-sa/4.0info:eu-repo/semantics/openAccessda Silva, Alisson Paulode Sousa, Felipe Gaiada Silva, Jennifer AragãoCalesso, Jéssica RagazziBeier, Suzane Lilian2024-08-02T14:03:50Zoai:ojs.10.0.7.8:article/6004Revistahttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/PUBhttps://www.journals.ufrpe.br/index.php/medicinaveterinaria/oairevmedvet@ufrpe.br1809-46782675-6617opendoar:2024-08-02T14:03:50Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)false
dc.title.none.fl_str_mv Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
Diagnóstico presuntivo de diabetes insipidus felina
title Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
spellingShingle Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
da Silva, Alisson Paulo
desmopressin
hyposthenuria
antidiuretic hormones
polydipsia
polyuria
desmopressina
hipostenúria
hormônio antidiurético
polidipsia
poliúria
title_short Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
title_full Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
title_fullStr Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
title_full_unstemmed Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
title_sort Presumptive diagnosis of central diabetes insipidus with possible origin secondary idiopathic etiology
author da Silva, Alisson Paulo
author_facet da Silva, Alisson Paulo
de Sousa, Felipe Gaia
da Silva, Jennifer Aragão
Calesso, Jéssica Ragazzi
Beier, Suzane Lilian
author_role author
author2 de Sousa, Felipe Gaia
da Silva, Jennifer Aragão
Calesso, Jéssica Ragazzi
Beier, Suzane Lilian
author2_role author
author
author
author
dc.contributor.author.fl_str_mv da Silva, Alisson Paulo
de Sousa, Felipe Gaia
da Silva, Jennifer Aragão
Calesso, Jéssica Ragazzi
Beier, Suzane Lilian
dc.subject.por.fl_str_mv desmopressin
hyposthenuria
antidiuretic hormones
polydipsia
polyuria
desmopressina
hipostenúria
hormônio antidiurético
polidipsia
poliúria
topic desmopressin
hyposthenuria
antidiuretic hormones
polydipsia
polyuria
desmopressina
hipostenúria
hormônio antidiurético
polidipsia
poliúria
description Diabetes insipidus (DI) is an infrequent endocrine disorder in cats caused by alteration in the synthesis and/or secretion of antidiuretic hormone (ADH), or by renal tubular inability to respond to the hormone. This endocrine disorder can have varied origins. The aim of this article was to report a case of diabetes insipidus in a 5-year-old mixed breed female cat, complaining of polyuria (PU) and polydipsia (PD), initially diagnosed as chronic kidney disease (CKD). The patient had already been evaluated by a professional, who found anemia, dehydration, azotemia and ultrasound changes suggestive of acute renal failure. Due to the concern of the owner, the patient was evaluated for another professional that observed a history, previous laboratory tests, and it was observed that the animal had a satisfactory body score, normal colored and hydrated mucous membranes, presence of gingivitis in the molar and premolar teeth, and moderate halitosis. The urinalysis showed isosthenuria, with no other alterations in the urinary analytes. Ultrasound examinations revealed maintenance of the corticomedullary architecture, discreet points of cortical mineralization and discreet dilation of the renal pelvis. The differentials of diabetes mellitus and hyperthyroidism were ruled out. Based on the clinical condition, diabetes insipidus was suspected, and the diagnosis was confirmed after a positive response to the use of desmopressin by the conjunctival route and increased urinary density.
publishDate 2024
dc.date.none.fl_str_mv 2024-08-02
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004
10.26605/medvet-v18n2-6004
url https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004
identifier_str_mv 10.26605/medvet-v18n2-6004
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.journals.ufrpe.br/index.php/medicinaveterinaria/article/view/6004/482485327
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MEDICINA VETERINÁRIA
publisher.none.fl_str_mv MEDICINA VETERINÁRIA
dc.source.none.fl_str_mv Medicina Veterinária; v. 18 n. 2 (2024): Medicina Veterinária; 138-142
2675-6617
1809-4678
10.26605/medvet-v18n2
reponame:Medicina Veterinária (Recife. Online)
instname:Universidade Federal Rural de Pernambuco (UFRPE)
instacron:UFRPE
instname_str Universidade Federal Rural de Pernambuco (UFRPE)
instacron_str UFRPE
institution UFRPE
reponame_str Medicina Veterinária (Recife. Online)
collection Medicina Veterinária (Recife. Online)
repository.name.fl_str_mv Medicina Veterinária (Recife. Online) - Universidade Federal Rural de Pernambuco (UFRPE)
repository.mail.fl_str_mv revmedvet@ufrpe.br
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