Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae)
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| Data de Publicação: | 2016 |
| Tipo de documento: | Tese |
| Idioma: | por |
| Título da fonte: | Biblioteca Digital de Teses e Dissertações da UFRRJ |
| Texto Completo: | https://rima.ufrrj.br/jspui/handle/20.500.14407/9221 |
Resumo: | O corpo gorduroso dos insetos está envolvido em funções de grande importância. Assim, o corpo gorduroso, além de atuar como sítio de reserva e síntese de proteínas, carboidratos e lipídios participa da produção de substâncias com ação no sistema imune, detoxificação, produção dos óvulos, espermatozoides e de feromônios. Contudo, a principal função do corpo gorduroso é a reserva de lipídios. O corpo gorduroso dos insetos normalmente é dividido em duas regiões, o corpo gorduroso visceral, localizado próximo do tubo digestivo, e o corpo gorduroso parietal, localizado próximo da cutícula. Os tipos celulares encontrados no corpo gorduroso dos insetos variam, sendo encontrado apenas um tipo em alguns e mais de dez tipos em outros. Os principais tipos celulares encontrados no corpo gorduroso dos insetos são os trofócitos, urócitos e os oenócitos. A morfologia e a bioquímica do corpo gorduroso de Lutzomyia longipalpis, o principal vetor da leishmaniose visceral nas Américas, foi analisado por microscopia de luz, microscopia eletrônica e cromatografia em camada fina de alta performance. Assim, cortes através do abdômen de machos e fêmeas adultas mostraram que o corpo gorduroso é dividido em dois componentes principais, de acordo com a distribuição espacial no corpo do inseto: uma parte parietal que está localizada logo abaixo da cutícula, e outra visceral que está distribuída em lóbulos suspensos e frequentemente associado a traqueias na hemocele. O corpo gorduroso de L. longipalpis contém somente um tipo celular, o trofócito, o qual possui grande quantidade de gotículas de lipídios, grânulos de proteína e rosetas de glicogênio em seu citoplasma. A composição lipídica varia de acordo com a condição fisiológica e espécie do inseto. O lipídio neutro estocado mais encontrado no corpo gorduroso de insetos é o triacilglicerol. Além disso, pequenas quantidades de diacilglicerol, esteroides, ácidos graxos livres, carotenoides e monoacilglicerois são transportadas por lipoforina (maior lipoproteína dos insetos). O diacilglicerol é derivado de triacilglicerois estocados no corpo gorduroso e constitui a principal forma de acido graxo que são mobilizadas para os sítios de utilização tal como os músculos de voo, por exemplo. A análise bioquímica dos tergitos abdominais de machos de L. longipalpis, através de Cromatografia em camada fina de alta performance, mostrou a presença de diferentes classes de lipídios neutros (mono-, di- e triacilglicerois, ácidos graxos, colesterol e colesterol esterificado) e fosfolipídios (fosfatidilcolina, fosfatidiletanolamina, fosfatidilinositol, lisofosfatidilcolina) no corpo gorduroso. Além disso, a composição lipídica entre os tergitos abdominais variou, sendo a maior quantidade de lipídios extraídos do quarto tergito, o qual possui glândulas produtoras de feromônio. Finalmente, o principal lipídio neutro extraído do corpo gorduroso de L. longipalpis foi o triacilglicerol e o principal fosfolipídio foi a fosfatidiletanolamina. |
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Bretas, Jorge Antônio CasagrandeMallet, Jacenir Reis dos Santos710.008.957-34Mallet, Jacenir Reis dos SantosFeder, Maria DeniseFreitas, Simone Carneiro deGomes, Suzete Araújo OliveiraSilva Junior, Renato da088.840.827-73http://lattes.cnpq.br/62482828676306622023-12-21T18:36:15Z2023-12-21T18:36:15Z2016-08-29BRETAS, Jorge Antônio Casagrande. Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae). 2016. 55 f. Tese (Doutorado em Biologia Animal). Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ. 2016.https://rima.ufrrj.br/jspui/handle/20.500.14407/9221O corpo gorduroso dos insetos está envolvido em funções de grande importância. Assim, o corpo gorduroso, além de atuar como sítio de reserva e síntese de proteínas, carboidratos e lipídios participa da produção de substâncias com ação no sistema imune, detoxificação, produção dos óvulos, espermatozoides e de feromônios. Contudo, a principal função do corpo gorduroso é a reserva de lipídios. O corpo gorduroso dos insetos normalmente é dividido em duas regiões, o corpo gorduroso visceral, localizado próximo do tubo digestivo, e o corpo gorduroso parietal, localizado próximo da cutícula. Os tipos celulares encontrados no corpo gorduroso dos insetos variam, sendo encontrado apenas um tipo em alguns e mais de dez tipos em outros. Os principais tipos celulares encontrados no corpo gorduroso dos insetos são os trofócitos, urócitos e os oenócitos. A morfologia e a bioquímica do corpo gorduroso de Lutzomyia longipalpis, o principal vetor da leishmaniose visceral nas Américas, foi analisado por microscopia de luz, microscopia eletrônica e cromatografia em camada fina de alta performance. Assim, cortes através do abdômen de machos e fêmeas adultas mostraram que o corpo gorduroso é dividido em dois componentes principais, de acordo com a distribuição espacial no corpo do inseto: uma parte parietal que está localizada logo abaixo da cutícula, e outra visceral que está distribuída em lóbulos suspensos e frequentemente associado a traqueias na hemocele. O corpo gorduroso de L. longipalpis contém somente um tipo celular, o trofócito, o qual possui grande quantidade de gotículas de lipídios, grânulos de proteína e rosetas de glicogênio em seu citoplasma. A composição lipídica varia de acordo com a condição fisiológica e espécie do inseto. O lipídio neutro estocado mais encontrado no corpo gorduroso de insetos é o triacilglicerol. Além disso, pequenas quantidades de diacilglicerol, esteroides, ácidos graxos livres, carotenoides e monoacilglicerois são transportadas por lipoforina (maior lipoproteína dos insetos). O diacilglicerol é derivado de triacilglicerois estocados no corpo gorduroso e constitui a principal forma de acido graxo que são mobilizadas para os sítios de utilização tal como os músculos de voo, por exemplo. A análise bioquímica dos tergitos abdominais de machos de L. longipalpis, através de Cromatografia em camada fina de alta performance, mostrou a presença de diferentes classes de lipídios neutros (mono-, di- e triacilglicerois, ácidos graxos, colesterol e colesterol esterificado) e fosfolipídios (fosfatidilcolina, fosfatidiletanolamina, fosfatidilinositol, lisofosfatidilcolina) no corpo gorduroso. Além disso, a composição lipídica entre os tergitos abdominais variou, sendo a maior quantidade de lipídios extraídos do quarto tergito, o qual possui glândulas produtoras de feromônio. Finalmente, o principal lipídio neutro extraído do corpo gorduroso de L. longipalpis foi o triacilglicerol e o principal fosfolipídio foi a fosfatidiletanolamina.CAPESThe fat body of insects is involved in very important functions. Thus, the fat body, besides acting as a reserve site and synthesis of proteins, carbohydrates and lipids participates in the production of substances with action on the immune system, detoxification, production of eggs, sperm and pheromone. However, the main function of the fat body is the reserve of lipids. The fat body of insects is usually divided into two regions, the visceral fat body, located near the digestive tract, and the parietal fat body, located near the cuticle. The cell types found in the fat body of insects vary, being found only one type in some and more than ten kinds in others. The main cell types found in the fat body of insects are trophocytes, urocytes and oenocytes. The morphology and biochemistry of fat body Lutzomyia longipalpis, the main vector of visceral leishmaniasis in the Americas, was examined by light microscopy, electron microscopy and high-performance thin layer chromatography. Thus, cuts through the abdomen of adult males and females showed that the fatty body is divided into two main components, in accordance with the spatial distribution in the insect's body: one parietal part which is located just under the cuticle and other visceral which is distributed suspended lobes and often associated with tracheas in hemocele. The fat body of L. longipalpis contains only one cell type, trophocyte, which has a large amount of lipid droplets, protein and glycogen granules in their cytoplasm rosettes. The lipid composition varies according to the physiological and insect species. The neutral lipid stored in fat body found more insects is the triacylglycerol. In addition, small amounts of diacylglycerol, steroids, free fatty acids, carotenoids and monoglycerides are carried by lipoforina (major lipoprotein of the insects). The diacylglycerol is derived from triglycerides stored in fat body and is the main form of fatty acid which are recruited to sites of utilization such as flight muscles, for example. Biochemical analysis of the abdominal tergites L. longipalpis males, by high-performance thin layer chromatography, showed the presence of different classes of neutral lipid (mono-, di- and triacylglycerols, fatty acids, cholesterol and esterified cholesterol) and phospholipids (phosphatidylcholine, phosphatidylethanolamine, phosphatidylinositol, lysophosphatidylcholine) in the fat body. Furthermore, the lipid composition of the abdominal tergites varied, with the highest amount of lipids extracted from the fourth tergite, which has pheromone producing gland. 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| dc.title.por.fl_str_mv |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| dc.title.alternative.eng.fl_str_mv |
Fat body of Lutzomyia longipalpis sandflies (Diptera: Psychodidae: Phlebotominae) |
| title |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| spellingShingle |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) Bretas, Jorge Antônio Casagrande fat body lipid composition Lutzomyia longipalpis sandflies ultrastructure corpo gorduroso composição lipídica Lutzomyia longipalpis flebotomíneos ultraestrutura Zoologia |
| title_short |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| title_full |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| title_fullStr |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| title_full_unstemmed |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| title_sort |
Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae) |
| author |
Bretas, Jorge Antônio Casagrande |
| author_facet |
Bretas, Jorge Antônio Casagrande |
| author_role |
author |
| dc.contributor.author.fl_str_mv |
Bretas, Jorge Antônio Casagrande |
| dc.contributor.advisor1.fl_str_mv |
Mallet, Jacenir Reis dos Santos |
| dc.contributor.advisor1ID.fl_str_mv |
710.008.957-34 |
| dc.contributor.referee1.fl_str_mv |
Mallet, Jacenir Reis dos Santos |
| dc.contributor.referee2.fl_str_mv |
Feder, Maria Denise |
| dc.contributor.referee3.fl_str_mv |
Freitas, Simone Carneiro de |
| dc.contributor.referee4.fl_str_mv |
Gomes, Suzete Araújo Oliveira |
| dc.contributor.referee5.fl_str_mv |
Silva Junior, Renato da |
| dc.contributor.authorID.fl_str_mv |
088.840.827-73 |
| dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/6248282867630662 |
| contributor_str_mv |
Mallet, Jacenir Reis dos Santos Mallet, Jacenir Reis dos Santos Feder, Maria Denise Freitas, Simone Carneiro de Gomes, Suzete Araújo Oliveira Silva Junior, Renato da |
| dc.subject.eng.fl_str_mv |
fat body lipid composition Lutzomyia longipalpis sandflies ultrastructure |
| topic |
fat body lipid composition Lutzomyia longipalpis sandflies ultrastructure corpo gorduroso composição lipídica Lutzomyia longipalpis flebotomíneos ultraestrutura Zoologia |
| dc.subject.por.fl_str_mv |
corpo gorduroso composição lipídica Lutzomyia longipalpis flebotomíneos ultraestrutura |
| dc.subject.cnpq.fl_str_mv |
Zoologia |
| description |
O corpo gorduroso dos insetos está envolvido em funções de grande importância. Assim, o corpo gorduroso, além de atuar como sítio de reserva e síntese de proteínas, carboidratos e lipídios participa da produção de substâncias com ação no sistema imune, detoxificação, produção dos óvulos, espermatozoides e de feromônios. Contudo, a principal função do corpo gorduroso é a reserva de lipídios. O corpo gorduroso dos insetos normalmente é dividido em duas regiões, o corpo gorduroso visceral, localizado próximo do tubo digestivo, e o corpo gorduroso parietal, localizado próximo da cutícula. Os tipos celulares encontrados no corpo gorduroso dos insetos variam, sendo encontrado apenas um tipo em alguns e mais de dez tipos em outros. Os principais tipos celulares encontrados no corpo gorduroso dos insetos são os trofócitos, urócitos e os oenócitos. A morfologia e a bioquímica do corpo gorduroso de Lutzomyia longipalpis, o principal vetor da leishmaniose visceral nas Américas, foi analisado por microscopia de luz, microscopia eletrônica e cromatografia em camada fina de alta performance. Assim, cortes através do abdômen de machos e fêmeas adultas mostraram que o corpo gorduroso é dividido em dois componentes principais, de acordo com a distribuição espacial no corpo do inseto: uma parte parietal que está localizada logo abaixo da cutícula, e outra visceral que está distribuída em lóbulos suspensos e frequentemente associado a traqueias na hemocele. O corpo gorduroso de L. longipalpis contém somente um tipo celular, o trofócito, o qual possui grande quantidade de gotículas de lipídios, grânulos de proteína e rosetas de glicogênio em seu citoplasma. A composição lipídica varia de acordo com a condição fisiológica e espécie do inseto. O lipídio neutro estocado mais encontrado no corpo gorduroso de insetos é o triacilglicerol. Além disso, pequenas quantidades de diacilglicerol, esteroides, ácidos graxos livres, carotenoides e monoacilglicerois são transportadas por lipoforina (maior lipoproteína dos insetos). O diacilglicerol é derivado de triacilglicerois estocados no corpo gorduroso e constitui a principal forma de acido graxo que são mobilizadas para os sítios de utilização tal como os músculos de voo, por exemplo. A análise bioquímica dos tergitos abdominais de machos de L. longipalpis, através de Cromatografia em camada fina de alta performance, mostrou a presença de diferentes classes de lipídios neutros (mono-, di- e triacilglicerois, ácidos graxos, colesterol e colesterol esterificado) e fosfolipídios (fosfatidilcolina, fosfatidiletanolamina, fosfatidilinositol, lisofosfatidilcolina) no corpo gorduroso. Além disso, a composição lipídica entre os tergitos abdominais variou, sendo a maior quantidade de lipídios extraídos do quarto tergito, o qual possui glândulas produtoras de feromônio. Finalmente, o principal lipídio neutro extraído do corpo gorduroso de L. longipalpis foi o triacilglicerol e o principal fosfolipídio foi a fosfatidiletanolamina. |
| publishDate |
2016 |
| dc.date.issued.fl_str_mv |
2016-08-29 |
| dc.date.accessioned.fl_str_mv |
2023-12-21T18:36:15Z |
| dc.date.available.fl_str_mv |
2023-12-21T18:36:15Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/doctoralThesis |
| format |
doctoralThesis |
| status_str |
publishedVersion |
| dc.identifier.citation.fl_str_mv |
BRETAS, Jorge Antônio Casagrande. Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae). 2016. 55 f. Tese (Doutorado em Biologia Animal). Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ. 2016. |
| dc.identifier.uri.fl_str_mv |
https://rima.ufrrj.br/jspui/handle/20.500.14407/9221 |
| identifier_str_mv |
BRETAS, Jorge Antônio Casagrande. Corpo gorduroso de Lutzomyia longipalpis (Díptera: Psichodidae: Phlebotominae). 2016. 55 f. Tese (Doutorado em Biologia Animal). Instituto de Ciências Biológicas e da Saúde, Universidade Federal Rural do Rio de Janeiro, Seropédica, RJ. 2016. |
| url |
https://rima.ufrrj.br/jspui/handle/20.500.14407/9221 |
| dc.language.iso.fl_str_mv |
por |
| language |
por |
| dc.relation.references.por.fl_str_mv |
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