Microsurgical treatment of patients with refractory epilepsy and mesial temporal cavernous malformations: clinical experience of a tertiary epilepsy center

• Autor(a) principal: Meguins, Lucas Crociati
• Data de Publicação: 2015
• Outros Autores: Adry, Rodrigo Antonio Rocha da Cruz, Silva Junior, Sebastião Carlos da, Pereira, Carlos Umberto, Oliveira, Jean Goncalves de, Morais, Dionei Freitas de, Araujo Filho, Gerardo Maria de, Marques, Lúcia Helena Neves
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFS
• Texto Completo: https://ri.ufs.br/handle/riufs/1972
• topic: Cavernous malformations; Mesiotemporal cavernous malformation; Temporal lobe epilepsy; Epilepsia do lobo temporal

Background: Mesiotemporal cavernous malformation can occur in 10–20% of patients with cerebral cavernomas and are frequently associated with refractory. Methods: A retrospective investigation was performed in the epilepsy clinic of a Brazilian tertiary referral epilepsy center, from January 2000 to March 2012. Results: A total of 21 patients were included in the study. Thirteen patients (62%) evolved to Engel I; 5 (24%) to Engel II, 2 (10%) to Engel III, and 1 (5%) to Engel IV. We observed that 10 (48%) patients with 12 years or less of epilepsy duration evolved to Engel I and 1 (5%) to Engel II; whereas from a total of 10 patients with epilepsy duration of more than 12 years, 3 (30%) evolved to Engel I and 7 (70%) to Engel II, III, or IV (P < 0.001 [bilateral]; P1 ≠ P2). Conclusion: Postsurgical seizure outcome for temporal lobe epilepsy associated with mesiotemporal cavernomas is very satisfactory.