Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/26915 |
Resumo: | Chikungunya fever (CF) is an arbovirosis caused by the Chikungunya virus (CHIKV). The main characteristic of CF is joint pain and more than half of infected patients experience chronic conditions. This case series study evaluated the persistent musculoskeletal presentations of CF in a sample of 72 patients with persistent symptoms (≥1 month) after CF confirmed by laboratory tests (detection of CHIKV by polymerase chain reaction [PCR] and/or immunoglobulin [Ig]M and/or IgG). The patients were followed up for 12 months after treatment at the outpatient clinic of the University Hospital of the Federal University of Sergipe (Hospital Universitário da Universidade Federal de Sergipe - HU/UFS). They were evaluated at admission and after 1 month, 2 months, and then every 3 months for up to 12 months. Painful and/or swollen joints, periarticular symptoms, other important findings on physical examination, and visual analogue pain scale (VAS) were evaluated during all consultations. Main results: Among the patients evaluated, 84.7% were female, the mean age was 53.8 years, and the mean duration of musculoskeletal complaints was 6 months. Comorbidities were present in 61.1% of patients and previous musculoskeletal disease was present in 69.4%. The most frequent presentation on admission was polyarticular, which occurred in 76.4% of cases. The most affected joints were the hands, knees, ankles, and feet. VAS on admission was intense in 66.7% of patients. Tenosynovitis was present in 44.5% of patients and was more frequently reported in the ankles. Corticosteroids and chloroquine were administered to 65.3% and 31.98% of patients, respectively. The findings indicated that persistent musculoskeletal presentations occur frequently after CF. These results provide a better understanding of patient profiles, musculoskeletal involvement, and CF progression, and may guide effective strategies for therapeutic management. |
id |
UNIFEI_a3f9cf31f8f4bbebe8a1a4f814411ec3 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/26915 |
network_acronym_str |
UNIFEI |
network_name_str |
Research, Society and Development |
repository_id_str |
|
spelling |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast BrazilPresentaciones musculoesqueléticas persistentes posfiebre chikungunya: una serie de casos en un estado del noreste de BrasilApresentações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do nordeste brasileiroArboviroseArtralgiaFebre Chikungunya.ArbovirusArtralgiaFiebre Chikungunya.ArbovirosisArthralgiaChikungunya fever.Chikungunya fever (CF) is an arbovirosis caused by the Chikungunya virus (CHIKV). The main characteristic of CF is joint pain and more than half of infected patients experience chronic conditions. This case series study evaluated the persistent musculoskeletal presentations of CF in a sample of 72 patients with persistent symptoms (≥1 month) after CF confirmed by laboratory tests (detection of CHIKV by polymerase chain reaction [PCR] and/or immunoglobulin [Ig]M and/or IgG). The patients were followed up for 12 months after treatment at the outpatient clinic of the University Hospital of the Federal University of Sergipe (Hospital Universitário da Universidade Federal de Sergipe - HU/UFS). They were evaluated at admission and after 1 month, 2 months, and then every 3 months for up to 12 months. Painful and/or swollen joints, periarticular symptoms, other important findings on physical examination, and visual analogue pain scale (VAS) were evaluated during all consultations. Main results: Among the patients evaluated, 84.7% were female, the mean age was 53.8 years, and the mean duration of musculoskeletal complaints was 6 months. Comorbidities were present in 61.1% of patients and previous musculoskeletal disease was present in 69.4%. The most frequent presentation on admission was polyarticular, which occurred in 76.4% of cases. The most affected joints were the hands, knees, ankles, and feet. VAS on admission was intense in 66.7% of patients. Tenosynovitis was present in 44.5% of patients and was more frequently reported in the ankles. Corticosteroids and chloroquine were administered to 65.3% and 31.98% of patients, respectively. The findings indicated that persistent musculoskeletal presentations occur frequently after CF. These results provide a better understanding of patient profiles, musculoskeletal involvement, and CF progression, and may guide effective strategies for therapeutic management.La fiebre chikungunya (FQ) es un arbovirus causado por el virus Chikungunya (CHIKV). La característica principal de la FQ es el dolor en las articulaciones y más de la mitad de los pacientes infectados tienen condiciones crónicas. Este estudio de serie de casos evaluó las presentaciones musculoesqueléticas persistentes de la FQ en una muestra de 72 pacientes con síntomas persistentes (rsimes) después de la FQ confirmada por laboratorio (reacción en cadena de la polimerasa [PCR] detección de CHIKV y/o inmunoglobulina [Ig]M y/ o IgG). Los pacientes fueron seguidos durante 12 meses después del tratamiento en la consulta externa del Hospital Universitario de la Universidad Federal de Sergipe (Hospital Universitario de la Universidad Federal de Sergipe - HU/UFS). Se evaluaron al ingreso y después de 1 mes, 2 meses y luego cada 3 meses hasta 12 meses. Articulaciones dolorosas y/o inflamadas, síntomas periarticulares, otros hallazgos importantes en el examen físico y la escala análoga visual del dolor (EVA) fueron evaluados durante todas las visitas. Principales resultados: Entre los pacientes evaluados, el 84,7% eran del sexo femenino, la edad media fue de 53,8 años y la duración media de las molestias musculoesqueléticas fue de 6 meses. Las comorbilidades estaban presentes en el 61,1% de los pacientes y la enfermedad musculoesquelética previa en el 69,4%. La presentación más frecuente al ingreso fue la poliarticular, que se presentó en el 76,4% de los casos. Las articulaciones más afectadas fueron las manos, rodillas, tobillos y pies. La EVA al ingreso fue intensa en el 66,7% de los pacientes. La tenosinovitis estuvo presente en el 44,5% de los pacientes y se notificó con mayor frecuencia en los tobillos. Se administraron corticoides y cloroquina al 65,3% y al 31,98% de los pacientes, respectivamente. Los hallazgos indicaron que las presentaciones musculoesqueléticas persistentes ocurren con frecuencia después de la FQ. Estos resultados proporcionan una mejor comprensión del perfil de los pacientes, la afectación musculoesquelética y la progresión de la FQ, y pueden orientar estrategias eficaces para el manejo terapéutico.A febre Chikungunya (FC) é uma arbovirose causada pelo vírus Chikungunya (CHIKV). A principal característica da FC é a dor nas articulações e mais da metade dos pacientes infectados apresentam condições crônicas. Este estudo de série de casos avaliou as apresentações musculoesqueléticas persistentes de FC em uma amostra de 72 pacientes com sintomas persistentes (rsimês) após FC confirmada por exames laboratoriais (detecção de CHIKV por reação em cadeia da polimerase [PCR] e/ou imunoglobulina [Ig]M e/ou IgG). Os pacientes foram acompanhados por 12 meses após o tratamento no ambulatório do Hospital Universitário da Universidade Federal de Sergipe (Hospital Universitário da Universidade Federal de Sergipe - HU/UFS). Eles foram avaliados na admissão e após 1 mês, 2 meses e depois a cada 3 meses por até 12 meses. Articulações dolorosas e/ou edemaciadas, sintomas periarticulares, outros achados importantes no exame físico e escala visual analógica de dor (EVA) foram avaliados durante todas as consultas. Principais resultados: Entre os pacientes avaliados, 84,7% eram do sexo feminino, a média de idade foi de 53,8 anos e a duração média das queixas musculoesqueléticas foi de 6 meses. Comorbidades estavam presentes em 61,1% dos pacientes e doença musculoesquelética prévia em 69,4%. A apresentação mais frequente na admissão foi a poliarticular, que ocorreu em 76,4% dos casos. As articulações mais acometidas foram as mãos, joelhos, tornozelos e pés. A EVA na admissão foi intensa em 66,7% dos pacientes. A tenossinovite esteve presente em 44,5% dos pacientes e foi mais frequentemente relatada nos tornozelos. Corticosteróides e cloroquina foram administrados a 65,3% e 31,98% dos pacientes, respectivamente. Os achados indicaram que as apresentações musculoesqueléticas persistentes ocorrem frequentemente após a FC. Esses resultados fornecem uma melhor compreensão do perfil dos pacientes, do envolvimento musculoesquelético e da progressão da FC, e podem orientar estratégias eficazes para o manejo terapêutico.Research, Society and Development2022-03-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2691510.33448/rsd-v11i3.26915Research, Society and Development; Vol. 11 No. 3; e56011326915Research, Society and Development; Vol. 11 Núm. 3; e56011326915Research, Society and Development; v. 11 n. 3; e560113269152525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/26915/23747Copyright (c) 2022 Alejandra Debbo; Vinícius Fernando Alves Carvalho; Ângela Maria da Silva; Roque de Almeida Pacheco; José Rodrigo Santos Silva; Weber de Santana Teles; Ruth Cristini Torres; Ângela Maria Melo Sá Barros; Max Cruz da Silva; Maria Hozana Santos Silvahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessDebbo, AlejandraCarvalho, Vinícius Fernando Alves Silva, Ângela Maria da Pacheco, Roque de Almeida Silva, José Rodrigo Santos Teles, Weber de Santana Torres, Ruth Cristini Barros, Ângela Maria Melo Sá Silva, Max Cruz da Silva, Maria Hozana Santos 2022-03-09T13:44:38Zoai:ojs.pkp.sfu.ca:article/26915Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:44:49.414119Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil Presentaciones musculoesqueléticas persistentes posfiebre chikungunya: una serie de casos en un estado del noreste de Brasil Apresentações musculoesqueléticas persistentes pós-febre chikungunya: uma série de casos em um estado do nordeste brasileiro |
title |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil |
spellingShingle |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil Debbo, Alejandra Arbovirose Artralgia Febre Chikungunya. Arbovirus Artralgia Fiebre Chikungunya. Arbovirosis Arthralgia Chikungunya fever. |
title_short |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil |
title_full |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil |
title_fullStr |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil |
title_full_unstemmed |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil |
title_sort |
Persistent musculoskeletal presentations post-chikungunya fever: a case series in a state in northeast Brazil |
author |
Debbo, Alejandra |
author_facet |
Debbo, Alejandra Carvalho, Vinícius Fernando Alves Silva, Ângela Maria da Pacheco, Roque de Almeida Silva, José Rodrigo Santos Teles, Weber de Santana Torres, Ruth Cristini Barros, Ângela Maria Melo Sá Silva, Max Cruz da Silva, Maria Hozana Santos |
author_role |
author |
author2 |
Carvalho, Vinícius Fernando Alves Silva, Ângela Maria da Pacheco, Roque de Almeida Silva, José Rodrigo Santos Teles, Weber de Santana Torres, Ruth Cristini Barros, Ângela Maria Melo Sá Silva, Max Cruz da Silva, Maria Hozana Santos |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Debbo, Alejandra Carvalho, Vinícius Fernando Alves Silva, Ângela Maria da Pacheco, Roque de Almeida Silva, José Rodrigo Santos Teles, Weber de Santana Torres, Ruth Cristini Barros, Ângela Maria Melo Sá Silva, Max Cruz da Silva, Maria Hozana Santos |
dc.subject.por.fl_str_mv |
Arbovirose Artralgia Febre Chikungunya. Arbovirus Artralgia Fiebre Chikungunya. Arbovirosis Arthralgia Chikungunya fever. |
topic |
Arbovirose Artralgia Febre Chikungunya. Arbovirus Artralgia Fiebre Chikungunya. Arbovirosis Arthralgia Chikungunya fever. |
description |
Chikungunya fever (CF) is an arbovirosis caused by the Chikungunya virus (CHIKV). The main characteristic of CF is joint pain and more than half of infected patients experience chronic conditions. This case series study evaluated the persistent musculoskeletal presentations of CF in a sample of 72 patients with persistent symptoms (≥1 month) after CF confirmed by laboratory tests (detection of CHIKV by polymerase chain reaction [PCR] and/or immunoglobulin [Ig]M and/or IgG). The patients were followed up for 12 months after treatment at the outpatient clinic of the University Hospital of the Federal University of Sergipe (Hospital Universitário da Universidade Federal de Sergipe - HU/UFS). They were evaluated at admission and after 1 month, 2 months, and then every 3 months for up to 12 months. Painful and/or swollen joints, periarticular symptoms, other important findings on physical examination, and visual analogue pain scale (VAS) were evaluated during all consultations. Main results: Among the patients evaluated, 84.7% were female, the mean age was 53.8 years, and the mean duration of musculoskeletal complaints was 6 months. Comorbidities were present in 61.1% of patients and previous musculoskeletal disease was present in 69.4%. The most frequent presentation on admission was polyarticular, which occurred in 76.4% of cases. The most affected joints were the hands, knees, ankles, and feet. VAS on admission was intense in 66.7% of patients. Tenosynovitis was present in 44.5% of patients and was more frequently reported in the ankles. Corticosteroids and chloroquine were administered to 65.3% and 31.98% of patients, respectively. The findings indicated that persistent musculoskeletal presentations occur frequently after CF. These results provide a better understanding of patient profiles, musculoskeletal involvement, and CF progression, and may guide effective strategies for therapeutic management. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-03-07 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26915 10.33448/rsd-v11i3.26915 |
url |
https://rsdjournal.org/index.php/rsd/article/view/26915 |
identifier_str_mv |
10.33448/rsd-v11i3.26915 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/26915/23747 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 11 No. 3; e56011326915 Research, Society and Development; Vol. 11 Núm. 3; e56011326915 Research, Society and Development; v. 11 n. 3; e56011326915 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052811108679680 |