Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)

Detalhes bibliográficos
Autor(a) principal: Goes, Tiago Costa
Data de Publicação: 2011
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/3759
Resumo: The aim of this study was to evaluate the potential anxiolytic effect of sweet orange aroma in healthy volunteers submitted to an anxiogenic situation. For this purpose, forty male volunteers, aged between 18 and 30 years, were allocated to five different groups (n=8) for the inhalation of sweet orange essential oil (test aroma: 2.5, 5 or 10 drops), Melaleuca alternifolia essential oil (control aroma: 2.5 drops) or distilled water (non-aromatic control: 2.5 drops). Immediately after inhalation, each volunteer was submitted to a model of anxiety, the video-monitored version of the Stroop Colour Word Test. Psychological parameters (state-anxiety, subjective tension, tranquilization and sedation) and physiological parameters (heart rate and gastrocnemius electromyogram) were evaluated before the inhalation period and before, during and after the test. The results of the psychological parameters were analyzed by Friedman s ANOVA, for each treatment group, followed by Tukey-type test for post hoc comparisons. The results of the physiological parameters were analyzed using a two-factor analysis of variance (ANOVA) for repeated measures followed by Tukey s test for post hoc comparisons. All significance tests were two-tailed and were performed at the 5% significance level. It s worth calling attention to the fact that the treatment s effect is revealed by the lack of significant alterations in the observed parameters throughout the test. Unlike the control groups, the individuals exposed to the test aroma in the doses of 2.5 drops and 10 drops did not present significant alterations (p > 0.05) in state anxiety, subjective tension and tranquillity levels throughout the anxiogenic situation, revealing an anxiolytic activity of sweet orange essential oil. Physiological alterations along the test were not prevented in any treatment group, as has previously been observed for diazepam. Although more studies are needed to find out the clinical relevance of aromatherapy for anxiety disorders, the present results indicate an acute anxiolytic activity of sweet orange aroma, giving some scientific support to its use as a tranquilizer by aromatherapists.
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spelling Goes, Tiago Costahttp://lattes.cnpq.br/9729753166045101Silva, Flavia Teixeirahttp://lattes.cnpq.br/50982000797517222017-09-26T12:17:10Z2017-09-26T12:17:10Z2011-11-23https://ri.ufs.br/handle/riufs/3759The aim of this study was to evaluate the potential anxiolytic effect of sweet orange aroma in healthy volunteers submitted to an anxiogenic situation. For this purpose, forty male volunteers, aged between 18 and 30 years, were allocated to five different groups (n=8) for the inhalation of sweet orange essential oil (test aroma: 2.5, 5 or 10 drops), Melaleuca alternifolia essential oil (control aroma: 2.5 drops) or distilled water (non-aromatic control: 2.5 drops). Immediately after inhalation, each volunteer was submitted to a model of anxiety, the video-monitored version of the Stroop Colour Word Test. Psychological parameters (state-anxiety, subjective tension, tranquilization and sedation) and physiological parameters (heart rate and gastrocnemius electromyogram) were evaluated before the inhalation period and before, during and after the test. The results of the psychological parameters were analyzed by Friedman s ANOVA, for each treatment group, followed by Tukey-type test for post hoc comparisons. The results of the physiological parameters were analyzed using a two-factor analysis of variance (ANOVA) for repeated measures followed by Tukey s test for post hoc comparisons. All significance tests were two-tailed and were performed at the 5% significance level. It s worth calling attention to the fact that the treatment s effect is revealed by the lack of significant alterations in the observed parameters throughout the test. Unlike the control groups, the individuals exposed to the test aroma in the doses of 2.5 drops and 10 drops did not present significant alterations (p > 0.05) in state anxiety, subjective tension and tranquillity levels throughout the anxiogenic situation, revealing an anxiolytic activity of sweet orange essential oil. Physiological alterations along the test were not prevented in any treatment group, as has previously been observed for diazepam. Although more studies are needed to find out the clinical relevance of aromatherapy for anxiety disorders, the present results indicate an acute anxiolytic activity of sweet orange aroma, giving some scientific support to its use as a tranquilizer by aromatherapists.O presente estudo teve por objetivo avaliar o potencial efeito ansiolítico do aroma de laranja doce (C. sinensis) em voluntários saudáveis submetidos a um modelo experimental de indução de ansiedade. Para tanto, quarenta voluntários do sexo masculino, com idade entre 18 e 30 anos, foram alocados em cinco diferentes grupos (n=8) para inalação do óleo essencial de laranja doce (aroma teste: 2,5, 5 ou 10 gotas), do óleo essencial de Melaleuca alternifolia (controle aromático: 2,5 gotas) ou de água destilada (controle não-aromático: 2,5 gotas). Imediatamente após a inalação, cada voluntário foi submetido à situação ansiogênica do Teste de Stroop Monitorado por Vídeo (TSMV), sendo que antes, durante e depois do TSMV foram realizadas medidas psicológicas (níveis de ansiedade-estado, de tensão subjetiva, de tranquilização e sedação) e fisiológicas (frequência cardíaca e eletromiograma do músculo gastrocnêmio). Todos estes parâmetros também foram avaliados previamente ao tratamento. Os resultados dos parâmetros psicológicos foram analisados por ANOVA de Friedman, para cada grupo de tratamento, seguido de teste a posteriori tipo Tukey. Já os resultados dos parâmetros fisiológicos foram analisados por ANOVA de duas vias para medidas repetidas, seguido de teste a posteriori de Tukey. Ambas as análises estatísticas foram realizadas com nível de significância de 5%. A existência de efeito ansiolítico deveria refletir-se nos resultados na forma de ausência de diferenças significativas entre as situações de teste. Assim sendo, diferentemente dos grupos controles, os grupos tratados com óleo de laranja doce nas doses de 2,5 e 10 gotas não apresentaram alterações significativas (p > 0,05) nos níveis de ansiedadeestado, tensão subjetiva e tranquilização ao longo do TSMV. Já em relação aos parâmetros fisiológicos, este efeito não foi observado, assim como ocorreu com o clássico ansiolítico, diazepam, em estudo anterior. Embora mais estudos sejam necessários para constatar a relevância clínica da aromaterapia no tratamento dos transtornos de ansiedade, os resultados do presente estudo demonstraram um efeito ansiolítico agudo do aroma de laranja doce, trazendo certo apoio científico para sua utilização como tranquilizante pelos aromaterapeutas.Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorapplication/pdfporUniversidade Federal de SergipePós-Graduação em Ciências da SaúdeUFSBRAnsiedadeAromaterapiaCitrus sinensisAnxietyAromatherapySweet orange oil essentialCNPQ::CIENCIAS DA SAUDEAvaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)EVALUATION OF THE POTENTIAL ANXIOLYTIC EFFECT OF SWEET ORANGE (CITRUS SINENSIS) AROMA.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSTEXTTIAGO_COSTA_GOES.pdf.txtTIAGO_COSTA_GOES.pdf.txtExtracted texttext/plain81504https://ri.ufs.br/jspui/bitstream/riufs/3759/2/TIAGO_COSTA_GOES.pdf.txtd3e7c9e587cee29929623cb6437541ebMD52THUMBNAILTIAGO_COSTA_GOES.pdf.jpgTIAGO_COSTA_GOES.pdf.jpgGenerated Thumbnailimage/jpeg1294https://ri.ufs.br/jspui/bitstream/riufs/3759/3/TIAGO_COSTA_GOES.pdf.jpg46504ba6b16c72310af87d5402b2443dMD53ORIGINALTIAGO_COSTA_GOES.pdfapplication/pdf859597https://ri.ufs.br/jspui/bitstream/riufs/3759/1/TIAGO_COSTA_GOES.pdf60af658eab6fd1af4a91b2c6aeb73cd0MD51riufs/37592017-11-28 16:12:48.097oai:ufs.br:riufs/3759Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-11-28T19:12:48Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.por.fl_str_mv Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
dc.title.alternative.eng.fl_str_mv EVALUATION OF THE POTENTIAL ANXIOLYTIC EFFECT OF SWEET ORANGE (CITRUS SINENSIS) AROMA.
title Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
spellingShingle Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
Goes, Tiago Costa
Ansiedade
Aromaterapia
Citrus sinensis
Anxiety
Aromatherapy
Sweet orange oil essential
CNPQ::CIENCIAS DA SAUDE
title_short Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
title_full Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
title_fullStr Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
title_full_unstemmed Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
title_sort Avaliação do potencial efeito ansiolítico do aroma de laranja doce (Citrus sinensis)
author Goes, Tiago Costa
author_facet Goes, Tiago Costa
author_role author
dc.contributor.author.fl_str_mv Goes, Tiago Costa
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9729753166045101
dc.contributor.advisor1.fl_str_mv Silva, Flavia Teixeira
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/5098200079751722
contributor_str_mv Silva, Flavia Teixeira
dc.subject.por.fl_str_mv Ansiedade
Aromaterapia
Citrus sinensis
topic Ansiedade
Aromaterapia
Citrus sinensis
Anxiety
Aromatherapy
Sweet orange oil essential
CNPQ::CIENCIAS DA SAUDE
dc.subject.eng.fl_str_mv Anxiety
Aromatherapy
Sweet orange oil essential
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS DA SAUDE
description The aim of this study was to evaluate the potential anxiolytic effect of sweet orange aroma in healthy volunteers submitted to an anxiogenic situation. For this purpose, forty male volunteers, aged between 18 and 30 years, were allocated to five different groups (n=8) for the inhalation of sweet orange essential oil (test aroma: 2.5, 5 or 10 drops), Melaleuca alternifolia essential oil (control aroma: 2.5 drops) or distilled water (non-aromatic control: 2.5 drops). Immediately after inhalation, each volunteer was submitted to a model of anxiety, the video-monitored version of the Stroop Colour Word Test. Psychological parameters (state-anxiety, subjective tension, tranquilization and sedation) and physiological parameters (heart rate and gastrocnemius electromyogram) were evaluated before the inhalation period and before, during and after the test. The results of the psychological parameters were analyzed by Friedman s ANOVA, for each treatment group, followed by Tukey-type test for post hoc comparisons. The results of the physiological parameters were analyzed using a two-factor analysis of variance (ANOVA) for repeated measures followed by Tukey s test for post hoc comparisons. All significance tests were two-tailed and were performed at the 5% significance level. It s worth calling attention to the fact that the treatment s effect is revealed by the lack of significant alterations in the observed parameters throughout the test. Unlike the control groups, the individuals exposed to the test aroma in the doses of 2.5 drops and 10 drops did not present significant alterations (p > 0.05) in state anxiety, subjective tension and tranquillity levels throughout the anxiogenic situation, revealing an anxiolytic activity of sweet orange essential oil. Physiological alterations along the test were not prevented in any treatment group, as has previously been observed for diazepam. Although more studies are needed to find out the clinical relevance of aromatherapy for anxiety disorders, the present results indicate an acute anxiolytic activity of sweet orange aroma, giving some scientific support to its use as a tranquilizer by aromatherapists.
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