Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | http://ri.ufs.br/jspui/handle/riufs/7599 |
Resumo: | Introduction: The clinical spectrum of thyroid nodules vary from an incidental and asymptomatic nodule, in 59 which cancer is the major concern, to clinically relevant nodules (= 1 cm) with compressive symptoms. This 60 study aims to compare clinical, ultrasonographic and cytological features of thyroid incidentalomas with 61 Materials and Methods: This cross-sectional retrospective study included 812 patients with thyroid 62 nodules, who underwent thyroid ultrasonography and Fine Needle Aspiration from January 2007 to 63 December 2013. We collected clinical and sonographic characteristics, and cytology was expressed 64 according to the Bethesda classification. Results: Of the 812 patients, 32.1% presented incidentalomas (< 1 65 cm). Thyroid incidentalomas presented as solid hypoechogenic and with peripheral vascularization lesions, 66 while nodules = 1 cm were mixed, hyperechogenic, with central and peripheral vascularization. Bethesda I 67 class was most commonly found among incidentalomas, and Bethesda II in the clinically relevant nodules’ 68 group. The frequency of malignant cytologies (Bethesda V and VI) was low in both groups. Conclusion: 69 Despite the ultrasound characteristics found in thyroid incidentalomas, they did not present a higher 70 frequency of suspicious or malignant cytologies. Instead, insufficient results were more frequent in this 71 group, which reinforces the current tendency to value suspicious sonographic characteristics altogether and 72 consider the possibility of follow-up of subcentimetric nodules. |
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Silva, Larissa FrancelinaRezende, Karla Freire2018-03-27T18:40:46Z2018-03-27T18:40:46Z2018-02-08SILVA, Larissa Francelina. Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes. Aracaju, SE, 2018. Monografia (Graduação em Medicina) - Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, 2018.http://ri.ufs.br/jspui/handle/riufs/7599Introduction: The clinical spectrum of thyroid nodules vary from an incidental and asymptomatic nodule, in 59 which cancer is the major concern, to clinically relevant nodules (= 1 cm) with compressive symptoms. This 60 study aims to compare clinical, ultrasonographic and cytological features of thyroid incidentalomas with 61 Materials and Methods: This cross-sectional retrospective study included 812 patients with thyroid 62 nodules, who underwent thyroid ultrasonography and Fine Needle Aspiration from January 2007 to 63 December 2013. We collected clinical and sonographic characteristics, and cytology was expressed 64 according to the Bethesda classification. Results: Of the 812 patients, 32.1% presented incidentalomas (< 1 65 cm). Thyroid incidentalomas presented as solid hypoechogenic and with peripheral vascularization lesions, 66 while nodules = 1 cm were mixed, hyperechogenic, with central and peripheral vascularization. Bethesda I 67 class was most commonly found among incidentalomas, and Bethesda II in the clinically relevant nodules’ 68 group. The frequency of malignant cytologies (Bethesda V and VI) was low in both groups. Conclusion: 69 Despite the ultrasound characteristics found in thyroid incidentalomas, they did not present a higher 70 frequency of suspicious or malignant cytologies. Instead, insufficient results were more frequent in this 71 group, which reinforces the current tendency to value suspicious sonographic characteristics altogether and 72 consider the possibility of follow-up of subcentimetric nodules.Introdução: O espectro clínico dos nódulos tireoidianos varia desde o nódulo incidental e assintomático, em 30 que a exclusão do câncer é a maior preocupação, até o nódulo clinicamente relevante (= 1 cm) com sintomas 31 compressivos. O objetivo deste estudo foi comparar as características clínicas, ultrassonográficas e 32 citológicas dos incidentalomas tireoidianos com os nódulos clinicamente relevantes (= 1 cm). Materiais e 33 Métodos: Estudo transversal e retrospectivo, incluiu 812 pacientes portadores de nódulos tireoidianos 34 submetidos à ultrassonografia da tireoide e Punção Aspirativa por Agulha Fina, no período de Janeiro de 35 2007 a Dezembro de 2013. Foram levantadas características clínicas e ultrassonográficas. A citologia foi 36 expressa de acordo com a classificação Bethesda. Resultados: Dos 812 pacientes, 32,1% apresentaram 37 incidentalomas (< 1 cm). Os incidentalomas apresentaram-se como nódulos sólidos, hipoecogênicos e com 38 vascularização periférica, enquanto os nódulos = 1 cm eram mais frequentemente mistos, hiperecogênicos, 39 com vascularização central e periférica. A classe Bethesda I foi mais encontrada no grupo dos 40 incidentalomas, enquanto a Bethesda II no dos clinicamente relevantes. A frequência de citologias malignas 41 (Bethesda V e VI) foi baixa em ambos os grupos. Conclusão: Apesar de os incidentalomas apresentarem 42 características ultrassonográficas tidas como suspeitas, estes não apresentaram maior frequência de citologias 43 suspeitas ou malignas, mas sim de resultados insuficientes, o que reforça a tendência atual de valorizar as 44 características ultrassonográficas suspeitas em conjunto e considerar a possibilidade de seguimento 45 ultrassonográfico dos nódulos subcentimétricos. 46 47Aracaju-(SE)porMedicinaSaúdeTireóide (tumores)CitologiaMedicineThyroid (tumors)CytologyCIENCIAS DA SAUDE::MEDICINAComparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantesComparison of the cytological pattern of incidentalomas in relation to clinically relevant thyroid nodulesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal de SergipeDME - Departamento de Medicina – Aracaju - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/7599/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALLarissa_Francelina_Silva.pdfLarissa_Francelina_Silva.pdfapplication/pdf780142https://ri.ufs.br/jspui/bitstream/riufs/7599/2/Larissa_Francelina_Silva.pdffb3279923bccec90b37888b2d2332f6cMD52TEXTLarissa_Francelina_Silva.pdf.txtLarissa_Francelina_Silva.pdf.txtExtracted texttext/plain103175https://ri.ufs.br/jspui/bitstream/riufs/7599/3/Larissa_Francelina_Silva.pdf.txt3cdfacebf3f8ffb4e2f1b9836e4da58bMD53THUMBNAILLarissa_Francelina_Silva.pdf.jpgLarissa_Francelina_Silva.pdf.jpgGenerated Thumbnailimage/jpeg1171https://ri.ufs.br/jspui/bitstream/riufs/7599/4/Larissa_Francelina_Silva.pdf.jpg683e6bb5448dce38e4e71944b9db52deMD54riufs/75992018-03-27 15:40:46.876oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2018-03-27T18:40:46Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
dc.title.alternative.eng.fl_str_mv |
Comparison of the cytological pattern of incidentalomas in relation to clinically relevant thyroid nodules |
title |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
spellingShingle |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes Silva, Larissa Francelina Medicina Saúde Tireóide (tumores) Citologia Medicine Thyroid (tumors) Cytology CIENCIAS DA SAUDE::MEDICINA |
title_short |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
title_full |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
title_fullStr |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
title_full_unstemmed |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
title_sort |
Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes |
author |
Silva, Larissa Francelina |
author_facet |
Silva, Larissa Francelina |
author_role |
author |
dc.contributor.author.fl_str_mv |
Silva, Larissa Francelina |
dc.contributor.advisor1.fl_str_mv |
Rezende, Karla Freire |
contributor_str_mv |
Rezende, Karla Freire |
dc.subject.por.fl_str_mv |
Medicina Saúde Tireóide (tumores) Citologia |
topic |
Medicina Saúde Tireóide (tumores) Citologia Medicine Thyroid (tumors) Cytology CIENCIAS DA SAUDE::MEDICINA |
dc.subject.eng.fl_str_mv |
Medicine Thyroid (tumors) Cytology |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::MEDICINA |
description |
Introduction: The clinical spectrum of thyroid nodules vary from an incidental and asymptomatic nodule, in 59 which cancer is the major concern, to clinically relevant nodules (= 1 cm) with compressive symptoms. This 60 study aims to compare clinical, ultrasonographic and cytological features of thyroid incidentalomas with 61 Materials and Methods: This cross-sectional retrospective study included 812 patients with thyroid 62 nodules, who underwent thyroid ultrasonography and Fine Needle Aspiration from January 2007 to 63 December 2013. We collected clinical and sonographic characteristics, and cytology was expressed 64 according to the Bethesda classification. Results: Of the 812 patients, 32.1% presented incidentalomas (< 1 65 cm). Thyroid incidentalomas presented as solid hypoechogenic and with peripheral vascularization lesions, 66 while nodules = 1 cm were mixed, hyperechogenic, with central and peripheral vascularization. Bethesda I 67 class was most commonly found among incidentalomas, and Bethesda II in the clinically relevant nodules’ 68 group. The frequency of malignant cytologies (Bethesda V and VI) was low in both groups. Conclusion: 69 Despite the ultrasound characteristics found in thyroid incidentalomas, they did not present a higher 70 frequency of suspicious or malignant cytologies. Instead, insufficient results were more frequent in this 71 group, which reinforces the current tendency to value suspicious sonographic characteristics altogether and 72 consider the possibility of follow-up of subcentimetric nodules. |
publishDate |
2018 |
dc.date.accessioned.fl_str_mv |
2018-03-27T18:40:46Z |
dc.date.available.fl_str_mv |
2018-03-27T18:40:46Z |
dc.date.issued.fl_str_mv |
2018-02-08 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
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bachelorThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
SILVA, Larissa Francelina. Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes. Aracaju, SE, 2018. Monografia (Graduação em Medicina) - Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, 2018. |
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http://ri.ufs.br/jspui/handle/riufs/7599 |
identifier_str_mv |
SILVA, Larissa Francelina. Comparação do padrão citológico de incidentalomas em relação a nódulos tireoidianos clinicamente relevantes. Aracaju, SE, 2018. Monografia (Graduação em Medicina) - Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, 2018. |
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Universidade Federal de Sergipe |
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DME - Departamento de Medicina – Aracaju - Presencial |
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