Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos
Autor(a) principal: | |
---|---|
Data de Publicação: | 2016 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | https://ri.ufs.br/handle/riufs/4000 |
Resumo: | Defensive responses vary according to the distance between prey and predator and the degree of threat that every situation offers. Studies suggest that the confrontation with the predator produces different types of analgesia as well as, the occurrence of anxiety and fear. The evaluate the effect of exposure of rat to different aversive conditions in defensive and nociceptive responses was our pursue. Therefore, we used 48 Wistar male rats weighing 250 to 350 g. On day 1, defensive and nociceptive responses of CTRL (without the cat's presence), GAt (active cat) and GIn (inactive cat) groups was evaluated. It was N = 16 animals per group, divided into groups with or without the possibility of escape to the shelter in the behavioral test arena (5 min), followed by hot plate test to measure the nociceptive response of rats. The following day (Day 2), all animals were returned to behavioral testing arena, for 5 min, to re-exposure to aversive environment (without the presence cat). GAt (p <0.01) and GIn (p = 0.03) groups had a significantly higher freezing time than CTRL. Additionally, GAt and GIn groups presented, respectively, shorter rearing (p <0.01; p = 0.02) and fewer quadrants crossing (p <0.01; p = 0.01). Farther, GAt group exhibited antinociceptive response at time 0, which was significantly different from baseline (p <0.01) and interval time 60 (p = 0.01). Still on day 2, GAt group had significantly higher freezing than GIn group (p= 0.04), additionally, the animals of GIn group, without the possibility of escape to the shelter, had higher rearing duration (p = 0.01) and number of quadrants intersections than CTRL and GAt groups without the possibility of escape to the shelter (p = 0.02; p < 0.02). GIn group showed a higher number of risk assessment than CTRL (p = 0.01). On day 2, no group showed significant antinociceptive response. The results suggest that cat's behavior has a direct influence on behavioral and nociceptive response of rats. In this sense, the presence of an active cat promoted the increase in freezing duration, the decrease exploratory activity and it induced antinociception responses in rats, besides promoting freezing responses in them after a re-exposure to aversive context. |
id |
UFS-2_6085486e921099712a2b1d07071c8e06 |
---|---|
oai_identifier_str |
oai:ufs.br:riufs/4000 |
network_acronym_str |
UFS-2 |
network_name_str |
Repositório Institucional da UFS |
repository_id_str |
|
spelling |
Magalhães, Marcus Vinícius FerreiraSilva, Luís Felipe Souza dahttp://lattes.cnpq.br/07834639197171112017-09-26T12:31:23Z2017-09-26T12:31:23Z2016-09-29MAGALHÃES, Marcus Vinícius Ferreira. Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos. 2016. 51 f. Dissertação (Pós-Graduação em Ciências Fisiológicas) - Universidade Federal de Sergipe, São Cristóvão, SE, 2016.https://ri.ufs.br/handle/riufs/4000Defensive responses vary according to the distance between prey and predator and the degree of threat that every situation offers. Studies suggest that the confrontation with the predator produces different types of analgesia as well as, the occurrence of anxiety and fear. The evaluate the effect of exposure of rat to different aversive conditions in defensive and nociceptive responses was our pursue. Therefore, we used 48 Wistar male rats weighing 250 to 350 g. On day 1, defensive and nociceptive responses of CTRL (without the cat's presence), GAt (active cat) and GIn (inactive cat) groups was evaluated. It was N = 16 animals per group, divided into groups with or without the possibility of escape to the shelter in the behavioral test arena (5 min), followed by hot plate test to measure the nociceptive response of rats. The following day (Day 2), all animals were returned to behavioral testing arena, for 5 min, to re-exposure to aversive environment (without the presence cat). GAt (p <0.01) and GIn (p = 0.03) groups had a significantly higher freezing time than CTRL. Additionally, GAt and GIn groups presented, respectively, shorter rearing (p <0.01; p = 0.02) and fewer quadrants crossing (p <0.01; p = 0.01). Farther, GAt group exhibited antinociceptive response at time 0, which was significantly different from baseline (p <0.01) and interval time 60 (p = 0.01). Still on day 2, GAt group had significantly higher freezing than GIn group (p= 0.04), additionally, the animals of GIn group, without the possibility of escape to the shelter, had higher rearing duration (p = 0.01) and number of quadrants intersections than CTRL and GAt groups without the possibility of escape to the shelter (p = 0.02; p < 0.02). GIn group showed a higher number of risk assessment than CTRL (p = 0.01). On day 2, no group showed significant antinociceptive response. The results suggest that cat's behavior has a direct influence on behavioral and nociceptive response of rats. In this sense, the presence of an active cat promoted the increase in freezing duration, the decrease exploratory activity and it induced antinociception responses in rats, besides promoting freezing responses in them after a re-exposure to aversive context.As respostas defensivas variam de acordo com a distância entre a presa e o predador e o grau de ameaça que cada situação oferece. Estudos sugerem que o confronto com o predador pode eliciar diferentes tipos de analgesia, bem como a ocorrência de ansiedade e medo. O nosso objetivo foi avaliar o efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos. Para tanto, foram utilizados 48 ratos Wistar com peso de 250 a 350 g. O experimento consistiu na avaliação das respostas defensivas de ratos dos grupos CTRL (sem a presença do gato), GAt (gato ativo) e GIn (gato inativo), N= 16 animais por grupo, divididos em grupos com ou sem a possibilidade de fuga para o abrigo na arena de teste comportamental, seguido do teste algesimétrico da placa quente para medir a influência da exposição ao gato na resposta nociceptiva dos ratos. No dia seguinte (dia 2), todos os animais voltaram à arena de teste comportamental para reexposição ao contexto aversivo (sem a presença do gato). Os grupos GAt (p< 0,01) e GIn (p= 0,03) apresentaram um tempo de congelamento significativamente maior que o CTRL, adicionalmente, os grupos GAt e GIn, apresentaram, respectivamente, menor tempo de rearing (p< 0,01; p= 0,02) e menor quantidade de cruzamento nos quadrantes (p< 0,01; p= 0,01), caracterizando uma menor atividade exploratória ou maior ansiedade. O grupo GAt apresentou resposta antinociceptiva no tempo 0, onde foi significativamente diferente do basal (p< 0,01) e do intervalo de tempo 60 (p= 0,01). No dia 2, o grupo GAt apresentou um tempo de congelamento significativamente maior que o grupo GIn (p= 0,04), paralelamente, os animais dos grupos GIn, sem a possibilidade de fuga para o abrigo, apresentaram um tempo de rearing (p= 0,01) e quantidade de cruzamentos nos quadrantes maiores que os grupos CTRL e GAt sem a possibilidade de fuga para o abrigo (p= 0,02; p< 0,02). O grupo GIn mostrou um número de tentativas ou avaliação de risco significativamente maior que o CTRL (p= 0,01). No dia 2, nenhum grupo apresentou resposta antinociceptiva significativa. Os resultados sugerem que o comportamento do gato tem influência direta na resposta comportamental e nociceptiva apresentada pelos ratos. Neste sentido, a presença de um gato ativo promoveu o aumento do tempo de congelamento, diminuiu a atividade exploratória, induziu respostas antinociceptivas em ratos e promoveu respostas de congelamento na reexposição dos ratos ao contexto aversivo.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESapplication/pdfporUniversidade Federal de SergipePós-Graduação em Ciências FisiológicasUFSBrasilFisiologiaAnalgesiaDorAnsiedadeMedoRespostas defensivasDefensive behaviorPainFearAnxietyCIENCIAS BIOLOGICAS::FISIOLOGIAEfeito do comportamento do gato nas respostas defensivas e nociceptivas de ratosEffect of cat's behavior in defensive and nociceptive responses of ratsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSORIGINALMARCUS_VINICIUS_F_MAGALHAES.pdfapplication/pdf924016https://ri.ufs.br/jspui/bitstream/riufs/4000/1/MARCUS_VINICIUS_F_MAGALHAES.pdf1de70329d30474ec950d4c115b15e371MD51TEXTMARCUS_VINICIUS_F_MAGALHAES.pdf.txtMARCUS_VINICIUS_F_MAGALHAES.pdf.txtExtracted texttext/plain98032https://ri.ufs.br/jspui/bitstream/riufs/4000/2/MARCUS_VINICIUS_F_MAGALHAES.pdf.txtc1a05a104ac5cb87df7382dc77dcda7eMD52THUMBNAILMARCUS_VINICIUS_F_MAGALHAES.pdf.jpgMARCUS_VINICIUS_F_MAGALHAES.pdf.jpgGenerated Thumbnailimage/jpeg1275https://ri.ufs.br/jspui/bitstream/riufs/4000/3/MARCUS_VINICIUS_F_MAGALHAES.pdf.jpg96ea470a6003b806a4c06011f44a54c1MD53riufs/40002017-11-24 21:45:26.635oai:ufs.br:riufs/4000Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-11-25T00:45:26Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.por.fl_str_mv |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
dc.title.alternative.eng.fl_str_mv |
Effect of cat's behavior in defensive and nociceptive responses of rats |
title |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
spellingShingle |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos Magalhães, Marcus Vinícius Ferreira Fisiologia Analgesia Dor Ansiedade Medo Respostas defensivas Defensive behavior Pain Fear Anxiety CIENCIAS BIOLOGICAS::FISIOLOGIA |
title_short |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
title_full |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
title_fullStr |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
title_full_unstemmed |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
title_sort |
Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos |
author |
Magalhães, Marcus Vinícius Ferreira |
author_facet |
Magalhães, Marcus Vinícius Ferreira |
author_role |
author |
dc.contributor.author.fl_str_mv |
Magalhães, Marcus Vinícius Ferreira |
dc.contributor.advisor1.fl_str_mv |
Silva, Luís Felipe Souza da |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/0783463919717111 |
contributor_str_mv |
Silva, Luís Felipe Souza da |
dc.subject.por.fl_str_mv |
Fisiologia Analgesia Dor Ansiedade Medo Respostas defensivas |
topic |
Fisiologia Analgesia Dor Ansiedade Medo Respostas defensivas Defensive behavior Pain Fear Anxiety CIENCIAS BIOLOGICAS::FISIOLOGIA |
dc.subject.eng.fl_str_mv |
Defensive behavior Pain Fear Anxiety |
dc.subject.cnpq.fl_str_mv |
CIENCIAS BIOLOGICAS::FISIOLOGIA |
description |
Defensive responses vary according to the distance between prey and predator and the degree of threat that every situation offers. Studies suggest that the confrontation with the predator produces different types of analgesia as well as, the occurrence of anxiety and fear. The evaluate the effect of exposure of rat to different aversive conditions in defensive and nociceptive responses was our pursue. Therefore, we used 48 Wistar male rats weighing 250 to 350 g. On day 1, defensive and nociceptive responses of CTRL (without the cat's presence), GAt (active cat) and GIn (inactive cat) groups was evaluated. It was N = 16 animals per group, divided into groups with or without the possibility of escape to the shelter in the behavioral test arena (5 min), followed by hot plate test to measure the nociceptive response of rats. The following day (Day 2), all animals were returned to behavioral testing arena, for 5 min, to re-exposure to aversive environment (without the presence cat). GAt (p <0.01) and GIn (p = 0.03) groups had a significantly higher freezing time than CTRL. Additionally, GAt and GIn groups presented, respectively, shorter rearing (p <0.01; p = 0.02) and fewer quadrants crossing (p <0.01; p = 0.01). Farther, GAt group exhibited antinociceptive response at time 0, which was significantly different from baseline (p <0.01) and interval time 60 (p = 0.01). Still on day 2, GAt group had significantly higher freezing than GIn group (p= 0.04), additionally, the animals of GIn group, without the possibility of escape to the shelter, had higher rearing duration (p = 0.01) and number of quadrants intersections than CTRL and GAt groups without the possibility of escape to the shelter (p = 0.02; p < 0.02). GIn group showed a higher number of risk assessment than CTRL (p = 0.01). On day 2, no group showed significant antinociceptive response. The results suggest that cat's behavior has a direct influence on behavioral and nociceptive response of rats. In this sense, the presence of an active cat promoted the increase in freezing duration, the decrease exploratory activity and it induced antinociception responses in rats, besides promoting freezing responses in them after a re-exposure to aversive context. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016-09-29 |
dc.date.accessioned.fl_str_mv |
2017-09-26T12:31:23Z |
dc.date.available.fl_str_mv |
2017-09-26T12:31:23Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
MAGALHÃES, Marcus Vinícius Ferreira. Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos. 2016. 51 f. Dissertação (Pós-Graduação em Ciências Fisiológicas) - Universidade Federal de Sergipe, São Cristóvão, SE, 2016. |
dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/4000 |
identifier_str_mv |
MAGALHÃES, Marcus Vinícius Ferreira. Efeito do comportamento do gato nas respostas defensivas e nociceptivas de ratos. 2016. 51 f. Dissertação (Pós-Graduação em Ciências Fisiológicas) - Universidade Federal de Sergipe, São Cristóvão, SE, 2016. |
url |
https://ri.ufs.br/handle/riufs/4000 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Sergipe |
dc.publisher.program.fl_str_mv |
Pós-Graduação em Ciências Fisiológicas |
dc.publisher.initials.fl_str_mv |
UFS |
dc.publisher.country.fl_str_mv |
Brasil |
publisher.none.fl_str_mv |
Universidade Federal de Sergipe |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UFS instname:Universidade Federal de Sergipe (UFS) instacron:UFS |
instname_str |
Universidade Federal de Sergipe (UFS) |
instacron_str |
UFS |
institution |
UFS |
reponame_str |
Repositório Institucional da UFS |
collection |
Repositório Institucional da UFS |
bitstream.url.fl_str_mv |
https://ri.ufs.br/jspui/bitstream/riufs/4000/1/MARCUS_VINICIUS_F_MAGALHAES.pdf https://ri.ufs.br/jspui/bitstream/riufs/4000/2/MARCUS_VINICIUS_F_MAGALHAES.pdf.txt https://ri.ufs.br/jspui/bitstream/riufs/4000/3/MARCUS_VINICIUS_F_MAGALHAES.pdf.jpg |
bitstream.checksum.fl_str_mv |
1de70329d30474ec950d4c115b15e371 c1a05a104ac5cb87df7382dc77dcda7e 96ea470a6003b806a4c06011f44a54c1 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS) |
repository.mail.fl_str_mv |
repositorio@academico.ufs.br |
_version_ |
1802110699956076544 |