Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom

Detalhes bibliográficos
Autor(a) principal: Meguins, Lucas Crociati
Data de Publicação: 2015
Outros Autores: Adry, Rodrigo Antonio Rocha da Cruz, Silva Junior, Sebastião Carlos da, Oliveira, Jean Goncalves de, Morais, Dionei Freitas de, Pereira, Carlos Umberto, Araujo Filho, Gerardo Maria de, Marques, Lúcia Helena Neves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFS
Texto Completo: https://ri.ufs.br/handle/riufs/1970
Resumo: Objective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom._________________________________________________________________________________________ RESUMO: Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises.
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spelling Meguins, Lucas CrociatiAdry, Rodrigo Antonio Rocha da CruzSilva Junior, Sebastião Carlos daOliveira, Jean Goncalves deMorais, Dionei Freitas dePereira, Carlos UmbertoAraujo Filho, Gerardo Maria deMarques, Lúcia Helena Neves2017-02-23T19:37:53Z2017-02-23T19:37:53Z2015-11MEGUINS, L. C. et al. Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 11, p. 924-928, nov. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924>. Acesso em: 23 fev. 2017.1678-4227https://ri.ufs.br/handle/riufs/1970Creative Commons Atribuição 4.0 InternacionalObjective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom._________________________________________________________________________________________ RESUMO: Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises.Academia Brasileira de Neurologia - ABNEUROTemporal low-grade gliomasIntractable epilepsyLong-term seizure outcomeGlioma temporal de baixo grauEpilepsia de difícil controleControle das crisesGross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedomA ressecção total de gliomas temporais de baixo grau é um importante fator no controle das crises convulsivasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILTemporalLowGradeGliomas.pdf.jpgTemporalLowGradeGliomas.pdf.jpgGenerated Thumbnailimage/jpeg1649https://ri.ufs.br/jspui/bitstream/riufs/1970/4/TemporalLowGradeGliomas.pdf.jpg3f6cbafe204ce30ff96a5be30ef6e8e3MD54ORIGINALTemporalLowGradeGliomas.pdfTemporalLowGradeGliomas.pdfapplication/pdf156880https://ri.ufs.br/jspui/bitstream/riufs/1970/1/TemporalLowGradeGliomas.pdff95eda9ce672596b7a16f7ab3675ea8eMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1970/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTTemporalLowGradeGliomas.pdf.txtTemporalLowGradeGliomas.pdf.txtExtracted texttext/plain26347https://ri.ufs.br/jspui/bitstream/riufs/1970/3/TemporalLowGradeGliomas.pdf.txt39d530cd6d2756e0308ace38ae99b9ecMD53riufs/19702017-02-24 02:00:20.11oai:ufs.br:riufs/1970Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-02-24T05:00:20Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
dc.title.alternative.pt_BR.fl_str_mv A ressecção total de gliomas temporais de baixo grau é um importante fator no controle das crises convulsivas
title Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
spellingShingle Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
Meguins, Lucas Crociati
Temporal low-grade gliomas
Intractable epilepsy
Long-term seizure outcome
Glioma temporal de baixo grau
Epilepsia de difícil controle
Controle das crises
title_short Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
title_full Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
title_fullStr Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
title_full_unstemmed Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
title_sort Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
author Meguins, Lucas Crociati
author_facet Meguins, Lucas Crociati
Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Pereira, Carlos Umberto
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
author_role author
author2 Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Pereira, Carlos Umberto
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Meguins, Lucas Crociati
Adry, Rodrigo Antonio Rocha da Cruz
Silva Junior, Sebastião Carlos da
Oliveira, Jean Goncalves de
Morais, Dionei Freitas de
Pereira, Carlos Umberto
Araujo Filho, Gerardo Maria de
Marques, Lúcia Helena Neves
dc.subject.por.fl_str_mv Temporal low-grade gliomas
Intractable epilepsy
Long-term seizure outcome
Glioma temporal de baixo grau
Epilepsia de difícil controle
Controle das crises
topic Temporal low-grade gliomas
Intractable epilepsy
Long-term seizure outcome
Glioma temporal de baixo grau
Epilepsia de difícil controle
Controle das crises
description Objective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom._________________________________________________________________________________________ RESUMO: Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises.
publishDate 2015
dc.date.issued.fl_str_mv 2015-11
dc.date.accessioned.fl_str_mv 2017-02-23T19:37:53Z
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dc.identifier.citation.fl_str_mv MEGUINS, L. C. et al. Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 11, p. 924-928, nov. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924>. Acesso em: 23 fev. 2017.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/1970
dc.identifier.issn.none.fl_str_mv 1678-4227
dc.identifier.license.pt_BR.fl_str_mv Creative Commons Atribuição 4.0 Internacional
identifier_str_mv MEGUINS, L. C. et al. Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 11, p. 924-928, nov. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924>. Acesso em: 23 fev. 2017.
1678-4227
Creative Commons Atribuição 4.0 Internacional
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