Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | https://ri.ufs.br/handle/riufs/1970 |
Resumo: | Objective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom._________________________________________________________________________________________ RESUMO: Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises. |
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Meguins, Lucas CrociatiAdry, Rodrigo Antonio Rocha da CruzSilva Junior, Sebastião Carlos daOliveira, Jean Goncalves deMorais, Dionei Freitas dePereira, Carlos UmbertoAraujo Filho, Gerardo Maria deMarques, Lúcia Helena Neves2017-02-23T19:37:53Z2017-02-23T19:37:53Z2015-11MEGUINS, L. C. et al. Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 11, p. 924-928, nov. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924>. Acesso em: 23 fev. 2017.1678-4227https://ri.ufs.br/handle/riufs/1970Creative Commons Atribuição 4.0 InternacionalObjective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom._________________________________________________________________________________________ RESUMO: Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises.Academia Brasileira de Neurologia - ABNEUROTemporal low-grade gliomasIntractable epilepsyLong-term seizure outcomeGlioma temporal de baixo grauEpilepsia de difícil controleControle das crisesGross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedomA ressecção total de gliomas temporais de baixo grau é um importante fator no controle das crises convulsivasinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTHUMBNAILTemporalLowGradeGliomas.pdf.jpgTemporalLowGradeGliomas.pdf.jpgGenerated Thumbnailimage/jpeg1649https://ri.ufs.br/jspui/bitstream/riufs/1970/4/TemporalLowGradeGliomas.pdf.jpg3f6cbafe204ce30ff96a5be30ef6e8e3MD54ORIGINALTemporalLowGradeGliomas.pdfTemporalLowGradeGliomas.pdfapplication/pdf156880https://ri.ufs.br/jspui/bitstream/riufs/1970/1/TemporalLowGradeGliomas.pdff95eda9ce672596b7a16f7ab3675ea8eMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748https://ri.ufs.br/jspui/bitstream/riufs/1970/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52TEXTTemporalLowGradeGliomas.pdf.txtTemporalLowGradeGliomas.pdf.txtExtracted texttext/plain26347https://ri.ufs.br/jspui/bitstream/riufs/1970/3/TemporalLowGradeGliomas.pdf.txt39d530cd6d2756e0308ace38ae99b9ecMD53riufs/19702017-02-24 02:00:20.11oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-02-24T05:00:20Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
dc.title.alternative.pt_BR.fl_str_mv |
A ressecção total de gliomas temporais de baixo grau é um importante fator no controle das crises convulsivas |
title |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
spellingShingle |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom Meguins, Lucas Crociati Temporal low-grade gliomas Intractable epilepsy Long-term seizure outcome Glioma temporal de baixo grau Epilepsia de difícil controle Controle das crises |
title_short |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
title_full |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
title_fullStr |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
title_full_unstemmed |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
title_sort |
Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom |
author |
Meguins, Lucas Crociati |
author_facet |
Meguins, Lucas Crociati Adry, Rodrigo Antonio Rocha da Cruz Silva Junior, Sebastião Carlos da Oliveira, Jean Goncalves de Morais, Dionei Freitas de Pereira, Carlos Umberto Araujo Filho, Gerardo Maria de Marques, Lúcia Helena Neves |
author_role |
author |
author2 |
Adry, Rodrigo Antonio Rocha da Cruz Silva Junior, Sebastião Carlos da Oliveira, Jean Goncalves de Morais, Dionei Freitas de Pereira, Carlos Umberto Araujo Filho, Gerardo Maria de Marques, Lúcia Helena Neves |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Meguins, Lucas Crociati Adry, Rodrigo Antonio Rocha da Cruz Silva Junior, Sebastião Carlos da Oliveira, Jean Goncalves de Morais, Dionei Freitas de Pereira, Carlos Umberto Araujo Filho, Gerardo Maria de Marques, Lúcia Helena Neves |
dc.subject.por.fl_str_mv |
Temporal low-grade gliomas Intractable epilepsy Long-term seizure outcome Glioma temporal de baixo grau Epilepsia de difícil controle Controle das crises |
topic |
Temporal low-grade gliomas Intractable epilepsy Long-term seizure outcome Glioma temporal de baixo grau Epilepsia de difícil controle Controle das crises |
description |
Objective: To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome. Method: A retrospective study was conducted with patients with temporal low-grade gliomas (LGG). Results: Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection. Conclusion: Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom._________________________________________________________________________________________ RESUMO: Objetivo: Apresentar uma série cirúrgica de pacientes com gliomas temporais de baixo grau, causando epilepsia de difícil controle. Método: Estudo retrospectivo de pacientes com diagnóstico de glioma temporal de baixo grau temporais. Resultados: 65 pacientes com foram operados em nossa instituição. A média de idade de início das crises foi de 25,7 ± 9,2 (11-66 anos). Após um ano de acompanhamento, quarenta e dois pacientes (64,6%) estavam Engel I; dezessete (26,2%) Engel II; quatro (6,2%) Engel III e dois (3,1%) Engel IV. Houve diferença estatisticamente significativa no resultado do controle das crises quando se compara a extensão da ressecção. Engel I foi observada em 39 pacientes (69,6%) com a ressecção total e em apenas 3 (33,3%) pacientes com ressecção parcial. Conclusão: A ressecção total de glioma temporal de baixo grau temporais é um fator extremamente importante no controle das crises. |
publishDate |
2015 |
dc.date.issued.fl_str_mv |
2015-11 |
dc.date.accessioned.fl_str_mv |
2017-02-23T19:37:53Z |
dc.date.available.fl_str_mv |
2017-02-23T19:37:53Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
MEGUINS, L. C. et al. Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 11, p. 924-928, nov. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924>. Acesso em: 23 fev. 2017. |
dc.identifier.uri.fl_str_mv |
https://ri.ufs.br/handle/riufs/1970 |
dc.identifier.issn.none.fl_str_mv |
1678-4227 |
dc.identifier.license.pt_BR.fl_str_mv |
Creative Commons Atribuição 4.0 Internacional |
identifier_str_mv |
MEGUINS, L. C. et al. Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom. Arquivos de Neuro-Psiquiatria, São Paulo, v. 73, n. 11, p. 924-928, nov. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924>. Acesso em: 23 fev. 2017. 1678-4227 Creative Commons Atribuição 4.0 Internacional |
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https://ri.ufs.br/handle/riufs/1970 |
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eng |
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Academia Brasileira de Neurologia - ABNEURO |
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Academia Brasileira de Neurologia - ABNEURO |
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