Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom

• Autor(a) principal: Meguins,Lucas Crociati
• Data de Publicação: 2015
• Outros Autores: Adry,Rodrigo Antônio Rocha da Cruz, Silva Júnior,Sebastião Carlos da, Pereira,Carlos Umberto, Oliveira,Jean Gonçalves de, Morais,Dionei Freitas de, Araújo Filho,Gerardo Maria de, Marques,Lúcia Helena Neves
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Arquivos de neuro-psiquiatria (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2015001100924
• topic: temporal low-grade gliomas; intractable epilepsy; long-term seizure outcome

Objective To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome.Method A retrospective study was conducted with patients with temporal low-grade gliomas (LGG).Results Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection.Conclusion Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom.