Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro

Detalhes bibliográficos
Autor(a) principal: Andrade, Yamaara Braga
Data de Publicação: 2016
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UFS
Texto Completo: http://ri.ufs.br/jspui/handle/riufs/10392
Resumo: Hyptis fruticosa is a sub-shrub belonging to the Lamiaceae family, commonly found in the Brazilian northeast coast and popularly used as a medicinal plant in the treatment for pain and other conditions. However, there are few reports on the biological activity of H. fruticosa and there are no reports of studies with its stem. On the context, this study is to provide the antioxidant profile in vitro of the Hyptis fruticosa stem ethanol extract (EEHF). In this study, was determined the content of total flavonoids and phenolic compounds, which showed significant concentrations in the plant. The antioxidant activity was determined by the radical scavenging of 2,2-difenil-1-picril-hidrazil (DPPH) and nitric oxide (NO), electron transfer capability by reducing potential (FRAP) and inhibition of lipid peroxidation by TBARS method, where EEHF showed good results in all tests at the concentrations tested. This study represents the first report on the antioxidant effect of Hyptis fruticosa stem and is intended to serve as support for future studies with the plant.
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spelling Andrade, Yamaara BragaDuarte, Marcelo Cavalcante2019-02-04T14:53:57Z2019-02-04T14:53:57Z2016-06-02ANDRADE, Yamaara Braga. Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro. São Cristóvão, SE, 2016. 1 CD-ROM Monografia (Bacharelado em Farmácia) - Departamento de Farmácia, Centro de Ciências Biológicas e da Saúde, Universidade Federal de Sergipe, São Cristóvão, 2016http://ri.ufs.br/jspui/handle/riufs/10392Hyptis fruticosa is a sub-shrub belonging to the Lamiaceae family, commonly found in the Brazilian northeast coast and popularly used as a medicinal plant in the treatment for pain and other conditions. However, there are few reports on the biological activity of H. fruticosa and there are no reports of studies with its stem. On the context, this study is to provide the antioxidant profile in vitro of the Hyptis fruticosa stem ethanol extract (EEHF). In this study, was determined the content of total flavonoids and phenolic compounds, which showed significant concentrations in the plant. The antioxidant activity was determined by the radical scavenging of 2,2-difenil-1-picril-hidrazil (DPPH) and nitric oxide (NO), electron transfer capability by reducing potential (FRAP) and inhibition of lipid peroxidation by TBARS method, where EEHF showed good results in all tests at the concentrations tested. This study represents the first report on the antioxidant effect of Hyptis fruticosa stem and is intended to serve as support for future studies with the plant.Hyptis fruticosa é um sub-arbusto pertencente à família Lamiaceae, comumente encontrado na costa do nordeste brasileiro e popularmente utilizado como planta medicinal no tratamento para dor e outras afecções. No entanto, ainda há poucos relatos sobre a atividade biológica de H. fruticosa e não há relatos sobre estudos com seu caule. Diante do contexto, esse trabalho consiste em fornecer o perfil antioxidante in vitro do extrato etanólico do caule de Hyptis fruticosa (EEHF). No presente estudo, foi determinado o teor de compostos fenólicos e flavonoides totais, que mostraram concentrações significantes na planta. A atividade antioxidante foi determinada pelos testes de varredura de radicais 2,2-difenil-1-picril-hidrazil (DPPH) e óxido nítrico (NO), capacidade de transferência de elétrons por potencial redutor (FRAP) e inibição da peroxidação lipídica pelo método TBARS, onde EEHF demonstrou boa resposta em todos os testes nas concentrações testadas. O presente estudo representa o primeiro relatório sobre o efeito antioxidante do caule de Hyptis fruticosa e tem o propósito de servir como suporte para futuros estudos com a plantaSão Cristóvão, SEporFarmáciaEnsino de farmáciaAntioxidantesLamiaceaeFlavonóidesFenóisHyptis fruticosaAntioxidant activityCIENCIAS BIOLOGICAS::FARMACOLOGIA::FARMACOLOGIA GERALAvaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitroinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal de SergipeDFA - Departamento de Farmácia – São Cristóvão - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTEXTYamaara_Braga_Andrade.pdf.txtYamaara_Braga_Andrade.pdf.txtExtracted texttext/plain30340https://ri.ufs.br/jspui/bitstream/riufs/10392/3/Yamaara_Braga_Andrade.pdf.txt17a19111f92a9473043cdd5996d0ed52MD53THUMBNAILYamaara_Braga_Andrade.pdf.jpgYamaara_Braga_Andrade.pdf.jpgGenerated Thumbnailimage/jpeg1197https://ri.ufs.br/jspui/bitstream/riufs/10392/4/Yamaara_Braga_Andrade.pdf.jpgbd13185d0509de4cd8e2a521c2d7d3feMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/10392/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALYamaara_Braga_Andrade.pdfYamaara_Braga_Andrade.pdfapplication/pdf482123https://ri.ufs.br/jspui/bitstream/riufs/10392/2/Yamaara_Braga_Andrade.pdfae88e6b310954fb4cd4fbaf9639ab1f8MD52riufs/103922019-02-04 11:53:57.901oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2019-02-04T14:53:57Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
title Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
spellingShingle Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
Andrade, Yamaara Braga
Farmácia
Ensino de farmácia
Antioxidantes
Lamiaceae
Flavonóides
Fenóis
Hyptis fruticosa
Antioxidant activity
CIENCIAS BIOLOGICAS::FARMACOLOGIA::FARMACOLOGIA GERAL
title_short Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
title_full Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
title_fullStr Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
title_full_unstemmed Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
title_sort Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro
author Andrade, Yamaara Braga
author_facet Andrade, Yamaara Braga
author_role author
dc.contributor.author.fl_str_mv Andrade, Yamaara Braga
dc.contributor.advisor1.fl_str_mv Duarte, Marcelo Cavalcante
contributor_str_mv Duarte, Marcelo Cavalcante
dc.subject.por.fl_str_mv Farmácia
Ensino de farmácia
Antioxidantes
Lamiaceae
Flavonóides
Fenóis
Hyptis fruticosa
topic Farmácia
Ensino de farmácia
Antioxidantes
Lamiaceae
Flavonóides
Fenóis
Hyptis fruticosa
Antioxidant activity
CIENCIAS BIOLOGICAS::FARMACOLOGIA::FARMACOLOGIA GERAL
dc.subject.eng.fl_str_mv Antioxidant activity
dc.subject.cnpq.fl_str_mv CIENCIAS BIOLOGICAS::FARMACOLOGIA::FARMACOLOGIA GERAL
description Hyptis fruticosa is a sub-shrub belonging to the Lamiaceae family, commonly found in the Brazilian northeast coast and popularly used as a medicinal plant in the treatment for pain and other conditions. However, there are few reports on the biological activity of H. fruticosa and there are no reports of studies with its stem. On the context, this study is to provide the antioxidant profile in vitro of the Hyptis fruticosa stem ethanol extract (EEHF). In this study, was determined the content of total flavonoids and phenolic compounds, which showed significant concentrations in the plant. The antioxidant activity was determined by the radical scavenging of 2,2-difenil-1-picril-hidrazil (DPPH) and nitric oxide (NO), electron transfer capability by reducing potential (FRAP) and inhibition of lipid peroxidation by TBARS method, where EEHF showed good results in all tests at the concentrations tested. This study represents the first report on the antioxidant effect of Hyptis fruticosa stem and is intended to serve as support for future studies with the plant.
publishDate 2016
dc.date.issued.fl_str_mv 2016-06-02
dc.date.accessioned.fl_str_mv 2019-02-04T14:53:57Z
dc.date.available.fl_str_mv 2019-02-04T14:53:57Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/bachelorThesis
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dc.identifier.citation.fl_str_mv ANDRADE, Yamaara Braga. Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro. São Cristóvão, SE, 2016. 1 CD-ROM Monografia (Bacharelado em Farmácia) - Departamento de Farmácia, Centro de Ciências Biológicas e da Saúde, Universidade Federal de Sergipe, São Cristóvão, 2016
dc.identifier.uri.fl_str_mv http://ri.ufs.br/jspui/handle/riufs/10392
identifier_str_mv ANDRADE, Yamaara Braga. Avaliação antioxidante do extrato etanólico do caule de Hyptis fruticosa Salzm ex. Benth : um estudo in vitro. São Cristóvão, SE, 2016. 1 CD-ROM Monografia (Bacharelado em Farmácia) - Departamento de Farmácia, Centro de Ciências Biológicas e da Saúde, Universidade Federal de Sergipe, São Cristóvão, 2016
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