Production of reactive oxygen species in macrophages treated with essential oil of Croton argyrophyllus Kunth

• Autor(a) principal: Araujo, Silvan Silva de
• Data de Publicação: 2014
• Outros Autores: Oliveira, Aline Camila Silva de, Santos, Matheus Ismerim Silva, Santos, Sandra Lauton, Amorim, Jamile Ferro de, Barreto, Emiliano de Oliveira, Cândido, Alexandre Luna, Araujo, Brancilene Santos de, Antoniolli, Ângelo Roberto, Estevam, Charles dos Santos
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFS
• Texto Completo: https://ri.ufs.br/handle/riufs/1646
• topic: Essential oil; Macrophages; Croton argyrophyllus Kunth

Essential oils are complex systems which consist mainly of volatile compounds of lipophilic source, as terpenes, sesquiterpenes and some non-terpenes [1]. Resulting from secondary metabolism, essential oil from Croton argyrophyllus (EOCA) is commonly extracted from its leaves. It is known that the essential oils from Croton species exhibit good antioxidant activity against DPPH free radical and reactive oxygen species (ROS) [2]. Several diseases are attributed to the increase of free radicals that show the importance of endogenous antioxidants like enzyme superoxide dismutase (SOD). Considering the use in folk medicine, it is relevant to find which concentration of EOCA has antioxidant effect against free radicals. To answer this question, the study aimed to evaluate ROS production in peritoneal macrophages of essential oil from C. argyrophyllus.