Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika

Detalhes bibliográficos
Autor(a) principal: Fontes, Yuri Rocha dos Santos
Data de Publicação: 2019
Tipo de documento: Trabalho de conclusão de curso
Idioma: por
Título da fonte: Repositório Institucional da UFS
Texto Completo: http://ri.ufs.br/jspui/handle/riufs/13241
Resumo: Objectives: The present study intends to describe the results of the ultrasonographic evaluation of the scrotum in children born with Congenital Zika Syndrome (CZS) followed at the Microcephaly Clinic of the Teaching Hospital of the Federal University of Sergipe, for the presence or absence of testicular atrophy and cryptorchidism and testicular volume of the subjects. Methods: This is a cross-sectional descriptive study conducted at the Microcephaly Clinic of the Teaching Hospital of the Federal University of Sergipe, with boys between 2 and 3 years of age with CZS. The testicular volume, the presence of cryptorchidism and testicular atrophy were determined by ultrasonographic imaging of the scrotum performed by a radiologist physician of the Teaching Hospital of the Federal University of Sergipe. The results were then organized for statistic analysis. Results: Of the 22 boys, 9 (41%) were classified as having bilateral or unilateral cryptorchidism; 13 (59%) had their testis inside the scrotum, in its normal position. The prevalence found of testicular atrophy was 73%, includind unilateral or bilateral cases. The mean testicular volume was 0,52mL. Conclusions: This study has shown high prevalences of testicular atrophy and cryptorchidism among children with CZS, in superior numbers than showed in available literature in healthy subjects. It was not possible to stablish a correlation between CZS and testicular atrophy, and more studies are needed to stablish a relation of causality between these two conditions; also, prospective studies are needed to evaluate the progression over longer periods of time of testicular atrophy and hypofertility.
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spelling Fontes, Yuri Rocha dos SantosFonseca, Adriana Barbosa de Lima2020-04-20T18:49:08Z2020-04-20T18:49:08Z2019-06-12FONTES, Yuri Rocha dos Santos. Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika. 2019. Trabalho de Conclusão de Curso (Graduação em Medicina) - Universidade Federal de Sergipe, Lagarto, 2019.http://ri.ufs.br/jspui/handle/riufs/13241Objectives: The present study intends to describe the results of the ultrasonographic evaluation of the scrotum in children born with Congenital Zika Syndrome (CZS) followed at the Microcephaly Clinic of the Teaching Hospital of the Federal University of Sergipe, for the presence or absence of testicular atrophy and cryptorchidism and testicular volume of the subjects. Methods: This is a cross-sectional descriptive study conducted at the Microcephaly Clinic of the Teaching Hospital of the Federal University of Sergipe, with boys between 2 and 3 years of age with CZS. The testicular volume, the presence of cryptorchidism and testicular atrophy were determined by ultrasonographic imaging of the scrotum performed by a radiologist physician of the Teaching Hospital of the Federal University of Sergipe. The results were then organized for statistic analysis. Results: Of the 22 boys, 9 (41%) were classified as having bilateral or unilateral cryptorchidism; 13 (59%) had their testis inside the scrotum, in its normal position. The prevalence found of testicular atrophy was 73%, includind unilateral or bilateral cases. The mean testicular volume was 0,52mL. Conclusions: This study has shown high prevalences of testicular atrophy and cryptorchidism among children with CZS, in superior numbers than showed in available literature in healthy subjects. It was not possible to stablish a correlation between CZS and testicular atrophy, and more studies are needed to stablish a relation of causality between these two conditions; also, prospective studies are needed to evaluate the progression over longer periods of time of testicular atrophy and hypofertility.Objetivo: Este estudo objetiva descrever resultados da avaliação testicular ultrassonográfica de meninos nascidos com Síndrome da Zika Congênita (SZC) acompanhados no Ambulatório de Microcefalia do Hospital Universitário da Universidade Federal de Sergipe, quanto à presença ou ausência de atrofia testicular e de criptorquidia, e determinação dos volumes testiculares dos sujeitos avaliados. Método: É um estudo transversal descritivo realizado no Ambulatório de Microcefalia do Hospital Universitário da Universidade Federal de Sergipe, com meninos de idade entre 2 e 3 anos portadores da SZC. O volume testicular, a criptorquidia e a atrofia testicular foram determinados através de ultrassonografias de saco escrotal realizadas por médico radiologista do Hospital Universitário – Universidade Federal de Sergipe. Os resultados foram tabelados para posterior análise estatística. Resultados: Dos 22 meninos avaliados, 9 deles (41%) foram classificados como possuidores de criptorquidia uni ou bilateral; 13 (59%) possuíam testículos tópicos em saco escrotal. A prevalência de atrofia testicular foi de 73%, incluindo atrofia uni ou bilateral. O volume testicular médio foi de 0,52mL. Conclusões: Este estudo mostrou altas prevalências de atrofia testicular e criptorquidia em meninos com SZC, superiores às descritas em literatura científica preexistente em sujeitos saudáveis. Não foi possível estabelecer uma relação de causalidade entre a SZC e a atrofia testicular, sendo necessários estudos adicionais que estabeleçam essa relação de causa e efeito, assim como estudos prospectivos que avaliem volume testicular e hipofertilidade a longo prazo.Lagarto - SEporLactentesZika virusMicrocefaliaCriptorquidismoInfecção pelo Zika vírusDoenças testicularesCruptorchidismZika virusZika virus infectionTesticular deseaseAvaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zikainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUFSDMEL - Departamento de Medicina Lagarto – Lagarto - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessTEXTYURI_ROCHA_DOS_SANTOS_FONTES.pdf.txtYURI_ROCHA_DOS_SANTOS_FONTES.pdf.txtExtracted texttext/plain58823https://ri.ufs.br/jspui/bitstream/riufs/13241/3/YURI_ROCHA_DOS_SANTOS_FONTES.pdf.txtdd13f2f7d0aa58169a850859fa9b8827MD53THUMBNAILYURI_ROCHA_DOS_SANTOS_FONTES.pdf.jpgYURI_ROCHA_DOS_SANTOS_FONTES.pdf.jpgGenerated Thumbnailimage/jpeg1224https://ri.ufs.br/jspui/bitstream/riufs/13241/4/YURI_ROCHA_DOS_SANTOS_FONTES.pdf.jpg19307ee905eba7dfd51086a424c91a74MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/13241/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51ORIGINALYURI_ROCHA_DOS_SANTOS_FONTES.pdfYURI_ROCHA_DOS_SANTOS_FONTES.pdfapplication/pdf415505https://ri.ufs.br/jspui/bitstream/riufs/13241/2/YURI_ROCHA_DOS_SANTOS_FONTES.pdf6febba8c1c8a67d8b2c3a123dd68ccd7MD52riufs/132412020-04-20 15:49:08.69oai:ufs.br:riufs/13241TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkNvbSBhIGFwcmVzZW50YcOnw6NvIGRlc3RhIGxpY2Vuw6dhLCB2b2PDqiAobyBhdXRvcihlcykgb3UgbyB0aXR1bGFyIGRvcyBkaXJlaXRvcyBkZSBhdXRvcikgY29uY2VkZSDDoCBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkZSBTZXJnaXBlIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSByZXByb2R1emlyIHNldSB0cmFiYWxobyBubyBmb3JtYXRvIGVsZXRyw7RuaWNvLCBpbmNsdWluZG8gb3MgZm9ybWF0b3Mgw6F1ZGlvIG91IHbDrWRlby4KClZvY8OqIGNvbmNvcmRhIHF1ZSBhIFVuaXZlcnNpZGFkZSBGZWRlcmFsIGRlIFNlcmdpcGUgcG9kZSwgc2VtIGFsdGVyYXIgbyBjb250ZcO6ZG8sIHRyYW5zcG9yIHNldSB0cmFiYWxobyBwYXJhIHF1YWxxdWVyIG1laW8gb3UgZm9ybWF0byBwYXJhIGZpbnMgZGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIHRhbWLDqW0gY29uY29yZGEgcXVlIGEgVW5pdmVyc2lkYWRlIEZlZGVyYWwgZGUgU2VyZ2lwZSBwb2RlIG1hbnRlciBtYWlzIGRlIHVtYSBjw7NwaWEgZGUgc2V1IHRyYWJhbGhvIHBhcmEgZmlucyBkZSBzZWd1cmFuw6dhLCBiYWNrLXVwIGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIGRlY2xhcmEgcXVlIHNldSB0cmFiYWxobyDDqSBvcmlnaW5hbCBlIHF1ZSB2b2PDqiB0ZW0gbyBwb2RlciBkZSBjb25jZWRlciBvcyBkaXJlaXRvcyBjb250aWRvcyBuZXN0YSBsaWNlbsOnYS4gVm9jw6ogdGFtYsOpbSBkZWNsYXJhIHF1ZSBvIGRlcMOzc2l0bywgcXVlIHNlamEgZGUgc2V1IGNvbmhlY2ltZW50bywgbsOjbyBpbmZyaW5nZSBkaXJlaXRvcyBhdXRvcmFpcyBkZSBuaW5ndcOpbS4KCkNhc28gbyB0cmFiYWxobyBjb250ZW5oYSBtYXRlcmlhbCBxdWUgdm9jw6ogbsOjbyBwb3NzdWkgYSB0aXR1bGFyaWRhZGUgZG9zIGRpcmVpdG9zIGF1dG9yYWlzLCB2b2PDqiBkZWNsYXJhIHF1ZSBvYnRldmUgYSBwZXJtaXNzw6NvIGlycmVzdHJpdGEgZG8gZGV0ZW50b3IgZG9zIGRpcmVpdG9zIGF1dG9yYWlzIHBhcmEgY29uY2VkZXIgw6AgVW5pdmVyc2lkYWRlIEZlZGVyYWwgZGUgU2VyZ2lwZSBvcyBkaXJlaXRvcyBhcHJlc2VudGFkb3MgbmVzdGEgbGljZW7Dp2EsIGUgcXVlIGVzc2UgbWF0ZXJpYWwgZGUgcHJvcHJpZWRhZGUgZGUgdGVyY2Vpcm9zIGVzdMOhIGNsYXJhbWVudGUgaWRlbnRpZmljYWRvIGUgcmVjb25oZWNpZG8gbm8gdGV4dG8gb3Ugbm8gY29udGXDumRvLgoKQSBVbml2ZXJzaWRhZGUgRmVkZXJhbCBkZSBTZXJnaXBlIHNlIGNvbXByb21ldGUgYSBpZGVudGlmaWNhciBjbGFyYW1lbnRlIG8gc2V1IG5vbWUocykgb3UgbyhzKSBub21lKHMpIGRvKHMpIApkZXRlbnRvcihlcykgZG9zIGRpcmVpdG9zIGF1dG9yYWlzIGRvIHRyYWJhbGhvLCBlIG7Do28gZmFyw6EgcXVhbHF1ZXIgYWx0ZXJhw6fDo28sIGFsw6ltIGRhcXVlbGFzIGNvbmNlZGlkYXMgcG9yIGVzdGEgbGljZW7Dp2EuIAo=Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2020-04-20T18:49:08Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.pt_BR.fl_str_mv Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
title Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
spellingShingle Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
Fontes, Yuri Rocha dos Santos
Lactentes
Zika virus
Microcefalia
Criptorquidismo
Infecção pelo Zika vírus
Doenças testiculares
Cruptorchidism
Zika virus
Zika virus infection
Testicular desease
title_short Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
title_full Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
title_fullStr Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
title_full_unstemmed Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
title_sort Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika
author Fontes, Yuri Rocha dos Santos
author_facet Fontes, Yuri Rocha dos Santos
author_role author
dc.contributor.author.fl_str_mv Fontes, Yuri Rocha dos Santos
dc.contributor.advisor1.fl_str_mv Fonseca, Adriana Barbosa de Lima
contributor_str_mv Fonseca, Adriana Barbosa de Lima
dc.subject.por.fl_str_mv Lactentes
Zika virus
Microcefalia
Criptorquidismo
Infecção pelo Zika vírus
Doenças testiculares
topic Lactentes
Zika virus
Microcefalia
Criptorquidismo
Infecção pelo Zika vírus
Doenças testiculares
Cruptorchidism
Zika virus
Zika virus infection
Testicular desease
dc.subject.eng.fl_str_mv Cruptorchidism
Zika virus
Zika virus infection
Testicular desease
description Objectives: The present study intends to describe the results of the ultrasonographic evaluation of the scrotum in children born with Congenital Zika Syndrome (CZS) followed at the Microcephaly Clinic of the Teaching Hospital of the Federal University of Sergipe, for the presence or absence of testicular atrophy and cryptorchidism and testicular volume of the subjects. Methods: This is a cross-sectional descriptive study conducted at the Microcephaly Clinic of the Teaching Hospital of the Federal University of Sergipe, with boys between 2 and 3 years of age with CZS. The testicular volume, the presence of cryptorchidism and testicular atrophy were determined by ultrasonographic imaging of the scrotum performed by a radiologist physician of the Teaching Hospital of the Federal University of Sergipe. The results were then organized for statistic analysis. Results: Of the 22 boys, 9 (41%) were classified as having bilateral or unilateral cryptorchidism; 13 (59%) had their testis inside the scrotum, in its normal position. The prevalence found of testicular atrophy was 73%, includind unilateral or bilateral cases. The mean testicular volume was 0,52mL. Conclusions: This study has shown high prevalences of testicular atrophy and cryptorchidism among children with CZS, in superior numbers than showed in available literature in healthy subjects. It was not possible to stablish a correlation between CZS and testicular atrophy, and more studies are needed to stablish a relation of causality between these two conditions; also, prospective studies are needed to evaluate the progression over longer periods of time of testicular atrophy and hypofertility.
publishDate 2019
dc.date.issued.fl_str_mv 2019-06-12
dc.date.accessioned.fl_str_mv 2020-04-20T18:49:08Z
dc.date.available.fl_str_mv 2020-04-20T18:49:08Z
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dc.identifier.citation.fl_str_mv FONTES, Yuri Rocha dos Santos. Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika. 2019. Trabalho de Conclusão de Curso (Graduação em Medicina) - Universidade Federal de Sergipe, Lagarto, 2019.
dc.identifier.uri.fl_str_mv http://ri.ufs.br/jspui/handle/riufs/13241
identifier_str_mv FONTES, Yuri Rocha dos Santos. Avaliação testicular em lactentes com síndrome da infecção congênita pelo vírus Zika. 2019. Trabalho de Conclusão de Curso (Graduação em Medicina) - Universidade Federal de Sergipe, Lagarto, 2019.
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