Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório Institucional da UFS |
Texto Completo: | http://ri.ufs.br/jspui/handle/riufs/12900 |
Resumo: | Visceral Leishmaniasis is an endemic disease in the northeastern Brazilian region, affecting approximately 1500 people in that region only this year. Sergipe presents itself as a state that is notably representative of this amount, counting on 55 cases and 9 deaths only in 2018 due to the disease. In view of this, is fundamental to study the clinical manifestations of Calazar in a regional context, comparing the descriptions available in the literature; with the purpose to better understand the profile of hospitalized patients at the University Hospital. This study allows to present a prospective descriptive study of cases series of patients at the University Hospital of Sergipe from 2016 to 2018 by Visceral Leishmaniasis; describing the main signs prevalence and disease symptoms as well as its remission from certain days after drug treatment. As a methodology, 53 patients were evaluated in the present study between 2016 and 2018, regarding the symptoms’ presence of fever, asthenia, weight loss, hyporexia, nausea, vomiting, diarrhea, constipation, abdominal pain, epistaxis, bleeding, hypocorous mucous membranes, jaundice, edema, ascites and adenomegaly; on days 0,7,21,30,60,90 and 180 subsequent from the start of drug treatment. Patients immunocompromised by HIV / AIDS or using immunosuppressive medications were excluded from the study. The diagnostic definition was based on the RK-39 rapid test and myelogram and / or bone marrow culture. From the evaluation of 53 patients, it was concluded that 68.3% were male and 31.7% were female. The mean age of inpatients was 28.84 years. The most prevalent symptoms were fever, asthenia, weight loss, and abdominal pain. The most symptoms resolution predominated between D0 and D7 after the beginning of the medication. The most commonly used treatment was liposomal amphotericin B; and the letality rate was 1.9%. |
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Ferreira, Nathalia Luisa CarlosAlmeida, Roque Pacheco2020-03-03T17:29:18Z2020-03-03T17:29:18Z2019-09-23FERREIRA, Nathalia Luisa Carlos. Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe. 2019. 52 f. Monografia (Graduação em Medicina) - Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, 2019.http://ri.ufs.br/jspui/handle/riufs/12900Visceral Leishmaniasis is an endemic disease in the northeastern Brazilian region, affecting approximately 1500 people in that region only this year. Sergipe presents itself as a state that is notably representative of this amount, counting on 55 cases and 9 deaths only in 2018 due to the disease. In view of this, is fundamental to study the clinical manifestations of Calazar in a regional context, comparing the descriptions available in the literature; with the purpose to better understand the profile of hospitalized patients at the University Hospital. This study allows to present a prospective descriptive study of cases series of patients at the University Hospital of Sergipe from 2016 to 2018 by Visceral Leishmaniasis; describing the main signs prevalence and disease symptoms as well as its remission from certain days after drug treatment. As a methodology, 53 patients were evaluated in the present study between 2016 and 2018, regarding the symptoms’ presence of fever, asthenia, weight loss, hyporexia, nausea, vomiting, diarrhea, constipation, abdominal pain, epistaxis, bleeding, hypocorous mucous membranes, jaundice, edema, ascites and adenomegaly; on days 0,7,21,30,60,90 and 180 subsequent from the start of drug treatment. Patients immunocompromised by HIV / AIDS or using immunosuppressive medications were excluded from the study. The diagnostic definition was based on the RK-39 rapid test and myelogram and / or bone marrow culture. From the evaluation of 53 patients, it was concluded that 68.3% were male and 31.7% were female. The mean age of inpatients was 28.84 years. The most prevalent symptoms were fever, asthenia, weight loss, and abdominal pain. The most symptoms resolution predominated between D0 and D7 after the beginning of the medication. The most commonly used treatment was liposomal amphotericin B; and the letality rate was 1.9%.A Leishmaniose Visceral e uma doença endêmica da região nordeste brasileira, acometendo cerca de 1500 pessoas somente nesta região todos os anos. Sergipe apresenta-se como um estado notadamente representativo deste montante, contando com 55 casos e 9 mortes somente em 2018 pela doença. Diante disso, é fundamental o estudo das manifestações clínicas do Calazar em contexto regional, comparando as descrições disponíveis na literatura.Este trabalho tem como objetivo apresentar um estudo prospectivo descritivo de uma série de casos de pacientes internados no Hospital Universitário de Sergipe de 2016 a 2018 por Leishmaniose Visceral; descrevendo prevalência dos principais sinais e sintomas da doença e sua resposta ao tratamento medicamentoso.Foram avaliados 53 pacientes internados no HU-UFS, entre 2016 e 2018, com relação à presença de sintomas de febre, astenia, perda de peso, hiporexia, náuseas, vômitos , diarreia, dor abdominal, epistaxe, sangramentos, presença de mucosas hipocoradas, icterícia, edema, ascite e adenomegalia; em vários dias subsequentes a partir do início do tratamento medicamentoso, denominados D0, D7, D14, D21, D30, D60, D90 e D180. Foram excluídos deste estudo pessoas imunodeprimidas por HIV/AIDS ou por uso de medicações imunossupressoras; e a definição diagnóstica foi baseada no teste rápido RK-39 e no resultado positivo de mielograma e/ou cultura de medula óssea. A partir da avaliação destes 53 pacientes, conclui-se que 68,3% por cento eram do sexo masculino e 31,7% por cento eram do sexo feminino. A idade média dos pacientes internados foi de 28,84 anos. Os sintomas mais prevalentes foram febre, astenia, perda de peso e dor abdominal. A resolutividade da maioria dos sintomas predominou entre o D0 e o D7 transcorridos do início da medicação. O tratamento mais utilizado foi a Anfotericina B lipossomal; e a taxa de letalidade foi de 1,9%.AracajuporLeishmaniose visceralCalazarLeishmania braziliensisZoonoseEpidemiologiaVisceral leishmaniosisZoononosesEpidemiologyCIENCIAS DA SAUDE::MEDICINAPerfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisUniversidade Federal de SergipeDME - Departamento de Medicina – Aracaju - Presencialreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSinfo:eu-repo/semantics/openAccessORIGINALNathalia_Luisa_Carlos_Ferreira.pdfNathalia_Luisa_Carlos_Ferreira.pdfapplication/pdf2949049https://ri.ufs.br/jspui/bitstream/riufs/12900/2/Nathalia_Luisa_Carlos_Ferreira.pdf58cbc61814fa1c2df92894b9731fc7f8MD52TEXTNathalia_Luisa_Carlos_Ferreira.pdf.txtNathalia_Luisa_Carlos_Ferreira.pdf.txtExtracted texttext/plain84836https://ri.ufs.br/jspui/bitstream/riufs/12900/3/Nathalia_Luisa_Carlos_Ferreira.pdf.txtc0994d14408ea55df6150ad55a1bad10MD53THUMBNAILNathalia_Luisa_Carlos_Ferreira.pdf.jpgNathalia_Luisa_Carlos_Ferreira.pdf.jpgGenerated Thumbnailimage/jpeg1276https://ri.ufs.br/jspui/bitstream/riufs/12900/4/Nathalia_Luisa_Carlos_Ferreira.pdf.jpg721530c43e3180d3f5f897ad2dac6da8MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-81475https://ri.ufs.br/jspui/bitstream/riufs/12900/1/license.txt098cbbf65c2c15e1fb2e49c5d306a44cMD51riufs/129002020-03-03 14:29:18.412oai:ufs.br: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Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2020-03-03T17:29:18Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false |
dc.title.pt_BR.fl_str_mv |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
title |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
spellingShingle |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe Ferreira, Nathalia Luisa Carlos Leishmaniose visceral Calazar Leishmania braziliensis Zoonose Epidemiologia Visceral leishmaniosis Zoononoses Epidemiology CIENCIAS DA SAUDE::MEDICINA |
title_short |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
title_full |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
title_fullStr |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
title_full_unstemmed |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
title_sort |
Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe |
author |
Ferreira, Nathalia Luisa Carlos |
author_facet |
Ferreira, Nathalia Luisa Carlos |
author_role |
author |
dc.contributor.author.fl_str_mv |
Ferreira, Nathalia Luisa Carlos |
dc.contributor.advisor1.fl_str_mv |
Almeida, Roque Pacheco |
contributor_str_mv |
Almeida, Roque Pacheco |
dc.subject.por.fl_str_mv |
Leishmaniose visceral Calazar Leishmania braziliensis Zoonose Epidemiologia |
topic |
Leishmaniose visceral Calazar Leishmania braziliensis Zoonose Epidemiologia Visceral leishmaniosis Zoononoses Epidemiology CIENCIAS DA SAUDE::MEDICINA |
dc.subject.eng.fl_str_mv |
Visceral leishmaniosis Zoononoses Epidemiology |
dc.subject.cnpq.fl_str_mv |
CIENCIAS DA SAUDE::MEDICINA |
description |
Visceral Leishmaniasis is an endemic disease in the northeastern Brazilian region, affecting approximately 1500 people in that region only this year. Sergipe presents itself as a state that is notably representative of this amount, counting on 55 cases and 9 deaths only in 2018 due to the disease. In view of this, is fundamental to study the clinical manifestations of Calazar in a regional context, comparing the descriptions available in the literature; with the purpose to better understand the profile of hospitalized patients at the University Hospital. This study allows to present a prospective descriptive study of cases series of patients at the University Hospital of Sergipe from 2016 to 2018 by Visceral Leishmaniasis; describing the main signs prevalence and disease symptoms as well as its remission from certain days after drug treatment. As a methodology, 53 patients were evaluated in the present study between 2016 and 2018, regarding the symptoms’ presence of fever, asthenia, weight loss, hyporexia, nausea, vomiting, diarrhea, constipation, abdominal pain, epistaxis, bleeding, hypocorous mucous membranes, jaundice, edema, ascites and adenomegaly; on days 0,7,21,30,60,90 and 180 subsequent from the start of drug treatment. Patients immunocompromised by HIV / AIDS or using immunosuppressive medications were excluded from the study. The diagnostic definition was based on the RK-39 rapid test and myelogram and / or bone marrow culture. From the evaluation of 53 patients, it was concluded that 68.3% were male and 31.7% were female. The mean age of inpatients was 28.84 years. The most prevalent symptoms were fever, asthenia, weight loss, and abdominal pain. The most symptoms resolution predominated between D0 and D7 after the beginning of the medication. The most commonly used treatment was liposomal amphotericin B; and the letality rate was 1.9%. |
publishDate |
2019 |
dc.date.issued.fl_str_mv |
2019-09-23 |
dc.date.accessioned.fl_str_mv |
2020-03-03T17:29:18Z |
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2020-03-03T17:29:18Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/bachelorThesis |
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bachelorThesis |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
FERREIRA, Nathalia Luisa Carlos. Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe. 2019. 52 f. Monografia (Graduação em Medicina) - Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, 2019. |
dc.identifier.uri.fl_str_mv |
http://ri.ufs.br/jspui/handle/riufs/12900 |
identifier_str_mv |
FERREIRA, Nathalia Luisa Carlos. Perfil clínico e epidemiológico de pacientes com leishmaniose visceral internados no Hospital Universitário de Sergipe. 2019. 52 f. Monografia (Graduação em Medicina) - Departamento de Medicina, Universidade Federal de Sergipe, Aracaju, 2019. |
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http://ri.ufs.br/jspui/handle/riufs/12900 |
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por |
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openAccess |
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Universidade Federal de Sergipe |
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DME - Departamento de Medicina – Aracaju - Presencial |
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