Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control.
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
Texto Completo: | https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103 |
Resumo: | Type 2 Diabetes mellitus (DM2) is a metabolic disease Type 2 Diabetes mellitus (DM2) is a metabolic disease characterized by hyperglycemia and cardiovascular dysfunctions that can be controlled with physical exercise, dietary control and pharmacological treatment. Recent research has demonstrated associations between DM2 and some genetic polymorphisms, especially alterations to the gene that codes for Angiotensin Converting Enzyme (ACE). The purpose of this study was to discuss the pathophysiology of DM2 and the use of physical exercise as a non-pharmacological method for controlling these patients’ glycemia and blood pressure. The relationship between DM2 and polymorphisms of the ACE gene was also covered. The literature search included textbooks in the healthcare field in addition to review articles and original articles found on the databases Pubmed, Scielo and Portal Capes. Keywords used were “blood glucose”, “type 2 diabetes”, “exercise”, “blood pressure” and “ACE gene polymorphism” and their translations in Portuguese. The main subject of this article is the practice of daily exercise, the types and intensities that have proven effective for glycemic and haemodinamic control and possible relationships with the ACE polymorphism, which are currently still tentative, since the evidence of associations can be strongly influenced by the population studied. The benefits of exercise are unquestionable and the recommended forms are discussed in this review. However the literature is still lacking studies that analyze the effects of physical exercise on diabetics and take into account the relationship with genetic aspects. This area is evidently an appropriate subject for further research. |
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Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control.Diabetes Mellitus tipo 2: Aspectos fisiológicos, genéticos e formas de exercício físico para seu controle.Type 2 Diabetes mellitus (DM2) is a metabolic disease Type 2 Diabetes mellitus (DM2) is a metabolic disease characterized by hyperglycemia and cardiovascular dysfunctions that can be controlled with physical exercise, dietary control and pharmacological treatment. Recent research has demonstrated associations between DM2 and some genetic polymorphisms, especially alterations to the gene that codes for Angiotensin Converting Enzyme (ACE). The purpose of this study was to discuss the pathophysiology of DM2 and the use of physical exercise as a non-pharmacological method for controlling these patients’ glycemia and blood pressure. The relationship between DM2 and polymorphisms of the ACE gene was also covered. The literature search included textbooks in the healthcare field in addition to review articles and original articles found on the databases Pubmed, Scielo and Portal Capes. Keywords used were “blood glucose”, “type 2 diabetes”, “exercise”, “blood pressure” and “ACE gene polymorphism” and their translations in Portuguese. The main subject of this article is the practice of daily exercise, the types and intensities that have proven effective for glycemic and haemodinamic control and possible relationships with the ACE polymorphism, which are currently still tentative, since the evidence of associations can be strongly influenced by the population studied. The benefits of exercise are unquestionable and the recommended forms are discussed in this review. However the literature is still lacking studies that analyze the effects of physical exercise on diabetics and take into account the relationship with genetic aspects. This area is evidently an appropriate subject for further research.Diabetes Mellitus tipo 2 (DM2) é uma doença metabólica caracterizada por hiperglicemia e disfunções cardiovasculares, as quais podem ser controladas com exercícios físicos, controle dietético e tratamento farmacológico. Pesquisas recentes têm demonstrado associações entre DM2 e alguns polimorfismos genéticos, em especial do gene da Enzima Conversora de Angiotensina (ECA). A proposta desse estudo foi abordar a fisiopatologia do DM2 e a prática de exercício físico como forma de controle não farmacológico da glicemia e pressão arterial destes pacientes, bem como a associação entre o DM2 e polimorfismos do gene da ECA. A pesquisa incluiu livros da área de saúde, bem como artigos de revisão e originais referentes ao tema abordado, pesquisados nos bancos de dados disponíveis na internet: Pubmed, Scielo e Portal Capes. As palavras chave utilizadas foram “blood glucose”, “type 2 diabetes”, “exercise”, “blood pressure” e “ACE gene polymorphism”, e suas traduções para a língua portuguesa. Os principais assuntos do presente artigo referem-se à prática diária de exercícios, tipo e intensidades adequadas que têm se mostrado eficazes no controle glicêmico e hemodinâmico, assim como as possíveis relações com os polimorfismos da ECA, que ainda se apresentam incipientes, pois a constatação de associações entre estes podem ser fortemente influenciadas pelo tipo de população estudada. Os benefícios do exercício são indiscutíveis e suas recomendações apresentadas nesta revisão. Porém a literatura ainda é carente de estudos analisando os efeitos do exercício físico para diabéticos, considerando sua relação com aspectos genéticos, o que coloca este assunto em evidência como objeto de estudo na atualidade.Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil2009-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion"Avaliado por Pares","Artigo Solicitado""Avaliado por Pares", "Artigo Solicitado"Experimentalapplication/pdfapplication/pdfhttps://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p10310.1590/1980-0037.2009v11n1p103Brazilian Journal of Kinanthropometry and Human Performance; Vol. 11 No. 1 (2009); 103-111Revista Brasileira de Cineantropometria e Desempenho Humano; v. 11 n. 1 (2009); 103-1111980-00371415-8426reponame:Revista Brasileira de Cineantropometria & Desempenho Humano (Online)instname:Universidade Federal de Santa Catarina (UFSC)instacron:UFSCporhttps://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103/7953https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103/16470Arsa, GiselaLima, LailaAlmeida, Sandro Soares deMoreira, Sérgio RodriguesCampbell, Carmen Sílvia GrubertSimões, Herbert Gustavoinfo:eu-repo/semantics/openAccess2020-01-22T10:12:44Zoai:periodicos.ufsc.br:article/8632Revistahttps://periodicos.ufsc.br/index.php/rbcdh/PUBhttps://periodicos.ufsc.br/index.php/rbcdh/oairbcdh@contato.ufsc.br || portaldeperiodicos.bu@contato.ufsc.br1980-00371415-8426opendoar:2020-01-22T10:12:44Revista Brasileira de Cineantropometria & Desempenho Humano (Online) - Universidade Federal de Santa Catarina (UFSC)false |
dc.title.none.fl_str_mv |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. Diabetes Mellitus tipo 2: Aspectos fisiológicos, genéticos e formas de exercício físico para seu controle. |
title |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. |
spellingShingle |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. Arsa, Gisela |
title_short |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. |
title_full |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. |
title_fullStr |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. |
title_full_unstemmed |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. |
title_sort |
Type 2 Diabetes Mellitus: Physiological and genetic aspects and the use of physical exercise for diabetes control. |
author |
Arsa, Gisela |
author_facet |
Arsa, Gisela Lima, Laila Almeida, Sandro Soares de Moreira, Sérgio Rodrigues Campbell, Carmen Sílvia Grubert Simões, Herbert Gustavo |
author_role |
author |
author2 |
Lima, Laila Almeida, Sandro Soares de Moreira, Sérgio Rodrigues Campbell, Carmen Sílvia Grubert Simões, Herbert Gustavo |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Arsa, Gisela Lima, Laila Almeida, Sandro Soares de Moreira, Sérgio Rodrigues Campbell, Carmen Sílvia Grubert Simões, Herbert Gustavo |
description |
Type 2 Diabetes mellitus (DM2) is a metabolic disease Type 2 Diabetes mellitus (DM2) is a metabolic disease characterized by hyperglycemia and cardiovascular dysfunctions that can be controlled with physical exercise, dietary control and pharmacological treatment. Recent research has demonstrated associations between DM2 and some genetic polymorphisms, especially alterations to the gene that codes for Angiotensin Converting Enzyme (ACE). The purpose of this study was to discuss the pathophysiology of DM2 and the use of physical exercise as a non-pharmacological method for controlling these patients’ glycemia and blood pressure. The relationship between DM2 and polymorphisms of the ACE gene was also covered. The literature search included textbooks in the healthcare field in addition to review articles and original articles found on the databases Pubmed, Scielo and Portal Capes. Keywords used were “blood glucose”, “type 2 diabetes”, “exercise”, “blood pressure” and “ACE gene polymorphism” and their translations in Portuguese. The main subject of this article is the practice of daily exercise, the types and intensities that have proven effective for glycemic and haemodinamic control and possible relationships with the ACE polymorphism, which are currently still tentative, since the evidence of associations can be strongly influenced by the population studied. The benefits of exercise are unquestionable and the recommended forms are discussed in this review. However the literature is still lacking studies that analyze the effects of physical exercise on diabetics and take into account the relationship with genetic aspects. This area is evidently an appropriate subject for further research. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion "Avaliado por Pares","Artigo Solicitado" "Avaliado por Pares", "Artigo Solicitado" Experimental |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103 10.1590/1980-0037.2009v11n1p103 |
url |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103 |
identifier_str_mv |
10.1590/1980-0037.2009v11n1p103 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103/7953 https://periodicos.ufsc.br/index.php/rbcdh/article/view/1980-0037.2009v11n1p103/16470 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil |
publisher.none.fl_str_mv |
Universidade Federal de Santa Catarina. Florianópolis, SC. Brasil |
dc.source.none.fl_str_mv |
Brazilian Journal of Kinanthropometry and Human Performance; Vol. 11 No. 1 (2009); 103-111 Revista Brasileira de Cineantropometria e Desempenho Humano; v. 11 n. 1 (2009); 103-111 1980-0037 1415-8426 reponame:Revista Brasileira de Cineantropometria & Desempenho Humano (Online) instname:Universidade Federal de Santa Catarina (UFSC) instacron:UFSC |
instname_str |
Universidade Federal de Santa Catarina (UFSC) |
instacron_str |
UFSC |
institution |
UFSC |
reponame_str |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
collection |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) |
repository.name.fl_str_mv |
Revista Brasileira de Cineantropometria & Desempenho Humano (Online) - Universidade Federal de Santa Catarina (UFSC) |
repository.mail.fl_str_mv |
rbcdh@contato.ufsc.br || portaldeperiodicos.bu@contato.ufsc.br |
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1789435121339727872 |